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Cerebral vascular disease in Hiroshima. Report of a six-year period of surveillance, 1958 to 1964

Abstract

Cerebral vascular disease (CVD) in the population of Hiroshima, Japan, is described for the period 1958 to 1964. The incidence of CVD in the male population over 30 years of age was 7.4 per 1000 per year and in females 4.1, approximately twice the observed incidence of coronary heart disease. Being based on examined individuals only, these estimates are biased downward, perhaps by a factor of 10%. The frequency of cerebral thrombosis was twice that of cerebral hemorrhage. These findings on incidence and type of CVD are in accord with the known high incidence of this disease in Japan but do not suggest that any disease other than atherosclerosis of the cerebral arteries is responsible. Hypertension, cardiomegaly (ascertained by ECG or chest film), and proteinuria were important factors in the risk of subsequent CVD. The singular association between hypertension and CVD, and the evidence that CVD is declining in Japan, the US and Europe during a period of widespread use of antihypertensive agents, encourage further epidemiologic study in CVD. 30 references, 15 figures, 8 tables.
Publication Date:
Aug 25, 1966
Product Type:
Technical Report
Report Number:
ABCC-TR-23-66
Reference Number:
EDB-84-058057
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; CARDIOVASCULAR DISEASES; ARTERIOSCLEROSIS; BRAIN; EXPERIMENTAL DATA; HEMORRHAGE; HIROSHIMA; HYPERTENSION; NERVOUS SYSTEM DISEASES; RADIATION HAZARDS; THROMBOSIS; ASIA; BODY; CENTRAL NERVOUS SYSTEM; DATA; DISEASES; HAZARDS; HEALTH HAZARDS; HUMAN POPULATIONS; INFORMATION; JAPAN; NERVOUS SYSTEM; NUMERICAL DATA; ORGANS; PATHOLOGICAL CHANGES; POPULATIONS; SYMPTOMS; VASCULAR DISEASES; 560151* - Radiation Effects on Animals- Man; 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5173983
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008150
Availability:
NTIS, PC A03/MF A01.
Submitting Site:
HEDB
Size:
Pages: 28
Announcement Date:
Apr 01, 1984

Citation Formats

Johnson, K G, Yano, Katsuhiko, and Kato, Hiroo. Cerebral vascular disease in Hiroshima. Report of a six-year period of surveillance, 1958 to 1964. Japan: N. p., 1966. Web.
Johnson, K G, Yano, Katsuhiko, & Kato, Hiroo. Cerebral vascular disease in Hiroshima. Report of a six-year period of surveillance, 1958 to 1964. Japan.
Johnson, K G, Yano, Katsuhiko, and Kato, Hiroo. 1966. "Cerebral vascular disease in Hiroshima. Report of a six-year period of surveillance, 1958 to 1964." Japan.
@misc{etde_5173983,
title = {Cerebral vascular disease in Hiroshima. Report of a six-year period of surveillance, 1958 to 1964}
author = {Johnson, K G, Yano, Katsuhiko, and Kato, Hiroo}
abstractNote = {Cerebral vascular disease (CVD) in the population of Hiroshima, Japan, is described for the period 1958 to 1964. The incidence of CVD in the male population over 30 years of age was 7.4 per 1000 per year and in females 4.1, approximately twice the observed incidence of coronary heart disease. Being based on examined individuals only, these estimates are biased downward, perhaps by a factor of 10%. The frequency of cerebral thrombosis was twice that of cerebral hemorrhage. These findings on incidence and type of CVD are in accord with the known high incidence of this disease in Japan but do not suggest that any disease other than atherosclerosis of the cerebral arteries is responsible. Hypertension, cardiomegaly (ascertained by ECG or chest film), and proteinuria were important factors in the risk of subsequent CVD. The singular association between hypertension and CVD, and the evidence that CVD is declining in Japan, the US and Europe during a period of widespread use of antihypertensive agents, encourage further epidemiologic study in CVD. 30 references, 15 figures, 8 tables.}
place = {Japan}
year = {1966}
month = {Aug}
}