You need JavaScript to view this

Search for the lowest irradiation dose from literatures on radiation-induced bone tumor

Journal Article:

Abstract

A survey of past case reports of bone tumor induced by external radiation was carried out with the main object of finding the lowest irradiation dose. Search of the literature published since 1922 revealed 262 cases of radiation-induced bone tumor. These patients, except a patient with occupational exposure, had received radiation for treatment. The primary conditions as object of radiation therapy were nonmalignan bone diseases such as tuberclosis, giant cell tumor, fibrous dysplasia and bone cyst, and extra-skeletal diseases such as retinoblastoma, breast cancer and uterus cancer. The ratio of male to female patients with radiation-induced bone tumor was 1:1.3. The age of the patient ranged between 5 and 98 years, with an average of 37.6 years. Skeletal distribution of radiation-induced bone tumor was as follows: 20% the frontal and face bones, 17% the femur, 10% the humerus, 9% the vertebral column, and 44% other. The lowest absorbed dose reported was 800 rads in patients irradiated for the treatment of bone disease, but 1800 rads in patients with extra-skeletal disease. The latent period ranged between 2 and 42 years, with an average of 11.7 years. The histopathological findings were as follows: 60% osteosarcoma, 25% fibrosarcoma, 7% chondrosarcoma, and 8% other.
Authors:
Yoshizawa, Y; Kusama, T; Morimoto, K [1] 
  1. Tokyo Univ. (Japan). Faculty of Medicine
Publication Date:
Apr 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-09-349774; EDB-78-070889
Resource Relation:
Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi; (Japan); Journal Volume: 37:4
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CARCINOGENESIS; LATENCY PERIOD; OSTEOSARCOMAS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; SKELETON; DELAYED RADIATION EFFECTS; AGE DEPENDENCE; BIBLIOGRAPHIES; LOW DOSE IRRADIATION; PATIENTS; RADIATION DOSES; SEX DEPENDENCE; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DISEASES; DOCUMENT TYPES; DOSES; IRRADIATION; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; PATHOGENESIS; RADIATION EFFECTS; RADIOLOGY; SARCOMAS; SKELETAL DISEASES; THERAPY; 560151* - Radiation Effects on Animals- Man
OSTI ID:
5141651
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NHGZA
Submitting Site:
INIS
Size:
Pages: 377-386
Announcement Date:

Journal Article:

Citation Formats

Yoshizawa, Y, Kusama, T, and Morimoto, K. Search for the lowest irradiation dose from literatures on radiation-induced bone tumor. Japan: N. p., 1977. Web.
Yoshizawa, Y, Kusama, T, & Morimoto, K. Search for the lowest irradiation dose from literatures on radiation-induced bone tumor. Japan.
Yoshizawa, Y, Kusama, T, and Morimoto, K. 1977. "Search for the lowest irradiation dose from literatures on radiation-induced bone tumor." Japan.
@misc{etde_5141651,
title = {Search for the lowest irradiation dose from literatures on radiation-induced bone tumor}
author = {Yoshizawa, Y, Kusama, T, and Morimoto, K}
abstractNote = {A survey of past case reports of bone tumor induced by external radiation was carried out with the main object of finding the lowest irradiation dose. Search of the literature published since 1922 revealed 262 cases of radiation-induced bone tumor. These patients, except a patient with occupational exposure, had received radiation for treatment. The primary conditions as object of radiation therapy were nonmalignan bone diseases such as tuberclosis, giant cell tumor, fibrous dysplasia and bone cyst, and extra-skeletal diseases such as retinoblastoma, breast cancer and uterus cancer. The ratio of male to female patients with radiation-induced bone tumor was 1:1.3. The age of the patient ranged between 5 and 98 years, with an average of 37.6 years. Skeletal distribution of radiation-induced bone tumor was as follows: 20% the frontal and face bones, 17% the femur, 10% the humerus, 9% the vertebral column, and 44% other. The lowest absorbed dose reported was 800 rads in patients irradiated for the treatment of bone disease, but 1800 rads in patients with extra-skeletal disease. The latent period ranged between 2 and 42 years, with an average of 11.7 years. The histopathological findings were as follows: 60% osteosarcoma, 25% fibrosarcoma, 7% chondrosarcoma, and 8% other.}
journal = {Nippon Igaku Hoshasen Gakkai Zasshi; (Japan)}
volume = {37:4}
journal type = {AC}
place = {Japan}
year = {1977}
month = {Apr}
}