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Some biochemical characteristics of a toxic substance isolated from organs of lethally irradiated animals in the course of the intestinal syndrome

Journal Article:

Abstract

A toxic substance isolated from organs of lethally irradiated (1300 rads) animals in the period when intestinal syndrome has developed is classified according to the parameters under study (namely, the molecular weight, UV-absorption curve, extinction coefficient, specific monosaccharides, the presence and percentage of KDA, etc.) as lipopolysaccharide of Escherichia coli, the main inhabitant of the gastroenteric tract of mice. That endotoxins (sensitivity to which is increased in this period of radiation sickness) are detected in the blood and organs of lethally irradiated animals, might indicate their participation in the pathogenesis of the intestinal syndrome.
Authors:
Meter, J D; Sirota, N S [1] 
  1. Tsentral'nyj Nauchno-Issledovatel'skij Rentgeno-Radiologicheskij Inst., Leningrad (USSR)
Publication Date:
May 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-09-362673; EDB-78-076041
Resource Relation:
Journal Name: Radiobiologiya; (USSR); Journal Volume: 16:3; Other Information: For English translation see the journal Radiobiology
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; BLOOD; ENDOTOXINS; BIOCHEMICAL REACTION KINETICS; GASTROINTESTINAL TRACT; CHEMICAL ANALYSIS; LETHAL IRRADIATION; MICE; PATHOGENESIS; ANIMALS; ANTIGENS; BIOLOGICAL MATERIALS; BODY FLUIDS; DIGESTIVE SYSTEM; IRRADIATION; KINETICS; MAMMALS; REACTION KINETICS; RODENTS; TOXIC MATERIALS; TOXINS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals; 550200 - Biochemistry
OSTI ID:
5089695
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: RADOA
Submitting Site:
INIS
Size:
Pages: 339-343
Announcement Date:
Mar 01, 1978

Journal Article:

Citation Formats

Meter, J D, and Sirota, N S. Some biochemical characteristics of a toxic substance isolated from organs of lethally irradiated animals in the course of the intestinal syndrome. USSR: N. p., 1976. Web.
Meter, J D, & Sirota, N S. Some biochemical characteristics of a toxic substance isolated from organs of lethally irradiated animals in the course of the intestinal syndrome. USSR.
Meter, J D, and Sirota, N S. 1976. "Some biochemical characteristics of a toxic substance isolated from organs of lethally irradiated animals in the course of the intestinal syndrome." USSR.
@misc{etde_5089695,
title = {Some biochemical characteristics of a toxic substance isolated from organs of lethally irradiated animals in the course of the intestinal syndrome}
author = {Meter, J D, and Sirota, N S}
abstractNote = {A toxic substance isolated from organs of lethally irradiated (1300 rads) animals in the period when intestinal syndrome has developed is classified according to the parameters under study (namely, the molecular weight, UV-absorption curve, extinction coefficient, specific monosaccharides, the presence and percentage of KDA, etc.) as lipopolysaccharide of Escherichia coli, the main inhabitant of the gastroenteric tract of mice. That endotoxins (sensitivity to which is increased in this period of radiation sickness) are detected in the blood and organs of lethally irradiated animals, might indicate their participation in the pathogenesis of the intestinal syndrome.}
journal = {Radiobiologiya; (USSR)}
volume = {16:3}
journal type = {AC}
place = {USSR}
year = {1976}
month = {May}
}