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Modulation of the noradrenergic receptor at uterine level by the 17. beta. -estradiol influence. Modulacao dos receptores noradrenergicos a nivel uterino sob influencia do 17. beta. -estradiol

Abstract

The present study was undertaken to asses the regulation of the noradrenergic receptor, by estrogens. We measured the uterotrophic response and the binding capacity of the noradrenergic receptor after the administration of 17 {beta}-estradiol (E sub(2); 132 nmol/kg b.w., i.p.) to immature rats. The results showed that 2 and 4 hs after E sub(2) treatment, the total number of NA-receptors enhanced significantly (6 fold). Similarly, it was observed a significant increase in uterine weight, 24 h after E sub(2) administration. The results indicate that NA-receptors present in the uterus may be under a direct E sub(2) regulation, which suggests a possible participation on the uterotropic response induced by E sub(2). (author).
Authors:
Vanderlei, F H.F.; Catanho, M T.J. [1] 
  1. Pernambuco Univ., Recife, PE (Brazil). Dept. Fisiologia e Farmacologia
Publication Date:
Jan 01, 1991
Product Type:
Miscellaneous
Report Number:
CONF-9105279-
Reference Number:
AIX-22-089555; EDB-91-163545
Resource Relation:
Conference: 1. Brazilian Meeting on Nuclear Applications, 1. Encontro Nacional de Aplicacoes Nucleares, Recife (Brazil), 27-30 May 1991; Related Information: In: Proceedings of the 1. Brazilian Meeting on Nuclear Applications - v. 2. Anais do 1. Encontro Nacional de Aplicacoes Nucleares - v. 2, 399 p
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; UTERUS; NORADRENALINE; RATS; TRITIUM; ESTRADIOL; ADRENAL HORMONES; ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENTS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOTONICS; CARDIOVASCULAR AGENTS; DRUGS; ESTRANES; ESTROGENS; FEMALE GENITALS; HORMONES; HYDROGEN ISOTOPES; HYDROXY COMPOUNDS; ISOTOPES; LIGHT NUCLEI; MAMMALS; NEUROREGULATORS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; RODENTS; STEROID HORMONES; STEROIDS; SYMPATHOMIMETICS; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 560162* - Radionuclide Effects, Kinetics, & Toxicology- Animals, Plants, Microorganisms, & Cells
OSTI ID:
5074619
Research Organizations:
Pernambuco Univ., Recife, PE (Brazil). Dept. de Energia Nuclear
Country of Origin:
Brazil
Language:
Portuguese
Availability:
Available from the Library of Comissao Nacional de Energia Nuclear, RJ, Brazil
Submitting Site:
INIS
Size:
Pages: 147-158; (399 p)
Announcement Date:
May 13, 2001

Citation Formats

Vanderlei, F H.F., and Catanho, M T.J. Modulation of the noradrenergic receptor at uterine level by the 17. beta. -estradiol influence. Modulacao dos receptores noradrenergicos a nivel uterino sob influencia do 17. beta. -estradiol. Brazil: N. p., 1991. Web.
Vanderlei, F H.F., & Catanho, M T.J. Modulation of the noradrenergic receptor at uterine level by the 17. beta. -estradiol influence. Modulacao dos receptores noradrenergicos a nivel uterino sob influencia do 17. beta. -estradiol. Brazil.
Vanderlei, F H.F., and Catanho, M T.J. 1991. "Modulation of the noradrenergic receptor at uterine level by the 17. beta. -estradiol influence. Modulacao dos receptores noradrenergicos a nivel uterino sob influencia do 17. beta. -estradiol." Brazil.
@misc{etde_5074619,
title = {Modulation of the noradrenergic receptor at uterine level by the 17. beta. -estradiol influence. Modulacao dos receptores noradrenergicos a nivel uterino sob influencia do 17. beta. -estradiol}
author = {Vanderlei, F H.F., and Catanho, M T.J.}
abstractNote = {The present study was undertaken to asses the regulation of the noradrenergic receptor, by estrogens. We measured the uterotrophic response and the binding capacity of the noradrenergic receptor after the administration of 17 {beta}-estradiol (E sub(2); 132 nmol/kg b.w., i.p.) to immature rats. The results showed that 2 and 4 hs after E sub(2) treatment, the total number of NA-receptors enhanced significantly (6 fold). Similarly, it was observed a significant increase in uterine weight, 24 h after E sub(2) administration. The results indicate that NA-receptors present in the uterus may be under a direct E sub(2) regulation, which suggests a possible participation on the uterotropic response induced by E sub(2). (author).}
place = {Brazil}
year = {1991}
month = {Jan}
}