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Radiation and DNA

Abstract

Consideration is given to the effects of ionizing radiation on the structure of DNA. Physical and chemical methods of determining radiation damage to the primary (polynucleotide chain and nitrogenous base) and secondary (helical) structure of DNA are discussed, and the effects of ionizing radiation on deoxyribonucleoprotein complexes are considered. The radiolysis of DNA in vitro and in bacterial and mammalian cells is examined and cellular mechanisms for the repair of radiation-damaged DNA are considered, taking into account single-strand and double-strand breaks, gamma-radiation damage and deoxyribonucleoprotein-membrane complex damage. Postradiation DNA degradation in bacteria and lymphatic cells is also discussed.
Authors:
Publication Date:
Jan 01, 1979
Product Type:
Book
Reference Number:
EDB-82-146761
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; DNA; RADIATION INJURIES; ANIMAL CELLS; BACTERIA; BIOCHEMISTRY; BIOPHYSICS; GAMMA RADIATION; IONIZING RADIATIONS; LYMPH; NUCLEOTIDES; RADIOBIOLOGY; RADIOLYSIS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BIOLOGY; BODY FLUIDS; CHEMICAL RADIATION EFFECTS; CHEMICAL REACTIONS; CHEMISTRY; DECOMPOSITION; ELECTROMAGNETIC RADIATION; INJURIES; MATERIALS; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION CHEMISTRY; RADIATION EFFECTS; RADIATIONS; 560110* - Radiation Effects on Biochemicals- (-1987)
OSTI ID:
5046938
Country of Origin:
USSR
Language:
Russian
Submitting Site:
HEDB
Size:
Pages: 192
Announcement Date:

Citation Formats

Riabchenko, N I. Radiation and DNA. USSR: N. p., 1979. Web.
Riabchenko, N I. Radiation and DNA. USSR.
Riabchenko, N I. 1979. "Radiation and DNA." USSR.
@misc{etde_5046938,
title = {Radiation and DNA}
author = {Riabchenko, N I}
abstractNote = {Consideration is given to the effects of ionizing radiation on the structure of DNA. Physical and chemical methods of determining radiation damage to the primary (polynucleotide chain and nitrogenous base) and secondary (helical) structure of DNA are discussed, and the effects of ionizing radiation on deoxyribonucleoprotein complexes are considered. The radiolysis of DNA in vitro and in bacterial and mammalian cells is examined and cellular mechanisms for the repair of radiation-damaged DNA are considered, taking into account single-strand and double-strand breaks, gamma-radiation damage and deoxyribonucleoprotein-membrane complex damage. Postradiation DNA degradation in bacteria and lymphatic cells is also discussed.}
place = {USSR}
year = {1979}
month = {Jan}
}