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Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli

Abstract

Three strains of Escherichia coli possessing the multiple drug resistance were found to be resistant also to HgCl/sub 2/, though they were sensitive to other heavy metal ions such as nickel, cobalt, cadmium and zinc ions. Like the resistance to drugs such as chloramphenicol and tetracycline, the HgCl/sub 2/ resistance could be transferred from a resistant strain of E. coli to sensitive strains of E. coli and Aerobacter aerogenes. The resistant strains could grow in the presence of 0.02 mM HgCl/sub 2/, whereas a sensitive strain failed to grow in the presence of 0.01 mM HgCl/sub 2/. During cultivation in the presence of HgCl/sub 2/, the cells of resistant strain vaporized a form of radioactive mercury when incubated with /sup 203/HgCl/sub 2/, glucose and NaCl in phosphate buffer while the cells of sensitive strain showed no such activity. This phenomenon seemed to explain the HgCl/sub 2/ resistance of the resistant strains.
Authors:
Publication Date:
Jan 01, 1971
Product Type:
Journal Article
Reference Number:
EDB-85-186367
Resource Relation:
Journal Name: J. Biochem. (Tokyo); (Japan); Journal Volume: 70
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ESCHERICHIA COLI; SENSITIVITY; MERCURY COMPOUNDS; EVAPORATION; AEROBACTER; ANTIBIOTICS; CADMIUM; COBALT; EXPERIMENTAL DATA; GROWTH; MERCURY 203; MERCURY CHLORIDES; METABOLISM; NICKEL; ZINC; ANTI-INFECTIVE AGENTS; BACTERIA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHLORIDES; CHLORINE COMPOUNDS; DATA; DAYS LIVING RADIOISOTOPES; DRUGS; ELEMENTS; EVEN-ODD NUCLEI; HALIDES; HALOGEN COMPOUNDS; HEAVY NUCLEI; INFORMATION; ISOTOPES; MERCURY HALIDES; MERCURY ISOTOPES; METALS; MICROORGANISMS; NUCLEI; NUMERICAL DATA; PHASE TRANSFORMATIONS; RADIOISOTOPES; TRANSITION ELEMENTS; 560302* - Chemicals Metabolism & Toxicology- Microorganisms- (-1987)
OSTI ID:
5018475
Research Organizations:
Tohoku Univ., Sendai, Japan
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JOBIA
Submitting Site:
HEDB
Size:
Pages: 885-893
Announcement Date:
Dec 01, 1985

Citation Formats

Komura, I, and Izaki, K. Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli. Japan: N. p., 1971. Web.
Komura, I, & Izaki, K. Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli. Japan.
Komura, I, and Izaki, K. 1971. "Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli." Japan.
@misc{etde_5018475,
title = {Mechanism of mercuric chloride resistance in microorganisms. I. Vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of Escherichia coli}
author = {Komura, I, and Izaki, K}
abstractNote = {Three strains of Escherichia coli possessing the multiple drug resistance were found to be resistant also to HgCl/sub 2/, though they were sensitive to other heavy metal ions such as nickel, cobalt, cadmium and zinc ions. Like the resistance to drugs such as chloramphenicol and tetracycline, the HgCl/sub 2/ resistance could be transferred from a resistant strain of E. coli to sensitive strains of E. coli and Aerobacter aerogenes. The resistant strains could grow in the presence of 0.02 mM HgCl/sub 2/, whereas a sensitive strain failed to grow in the presence of 0.01 mM HgCl/sub 2/. During cultivation in the presence of HgCl/sub 2/, the cells of resistant strain vaporized a form of radioactive mercury when incubated with /sup 203/HgCl/sub 2/, glucose and NaCl in phosphate buffer while the cells of sensitive strain showed no such activity. This phenomenon seemed to explain the HgCl/sub 2/ resistance of the resistant strains.}
journal = []
volume = {70}
journal type = {AC}
place = {Japan}
year = {1971}
month = {Jan}
}