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Studies on the mercuric chloride resistance of Staphylococcus aureus

Abstract

Among 409 pathogenic Staph. aureus strains 34% have been found to be sensitive, and 66% resistant, to mercuric chloride. The incidence of mercuric chloride resistant cultures among antibiotic sensitive staphylococci was 20%; among strains resistant to penicillin or to more than one antibiotic, 70%. Mercuric chloride resistant organisms occurred chiefly among phage group I and untypable strains; they were especially common among the so called epidemic strains of phage group I, and among cultures resistant to 4-6 antibiotics. In mercuric chloride sensitivity a thirtyfold, in merthiolate sensitivity only a two-fold difference has been revealed among the strains. The sulfydryl group content of mercuric chloride resistant organisms was only 1 1/2 times higher than that of sensitive bacteria. As to p-chlor mercuric benzoate binding capacity, a twofold difference was found between mercuric chloride sensitive and resistant staphylococci. The differences in the mercuric chloride resistance of various staphylococcal strains might be due to differences in the chemical structure of the cell surface. 9 references, 1 figure, 6 tables.
Publication Date:
Jan 01, 1962
Product Type:
Journal Article
Reference Number:
EDB-85-177922
Resource Relation:
Journal Name: Acta Microbiol. Acad. Sci. Hung.; (Hungary); Journal Volume: 9:1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; MERCURY CHLORIDES; BIOLOGICAL EFFECTS; STAPHYLOCOCCUS; SENSITIVITY; ANTIBIOTICS; BIOCHEMISTRY; COMPARATIVE EVALUATIONS; ANTI-INFECTIVE AGENTS; BACTERIA; CHEMISTRY; CHLORIDES; CHLORINE COMPOUNDS; DRUGS; HALIDES; HALOGEN COMPOUNDS; MERCURY COMPOUNDS; MERCURY HALIDES; MICROORGANISMS; 560302* - Chemicals Metabolism & Toxicology- Microorganisms- (-1987); 550700 - Microbiology
OSTI ID:
5017592
Research Organizations:
Univ. Medical School, Debrecen, Hungary
Country of Origin:
Hungary
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: AMAHA
Submitting Site:
HEDB
Size:
Pages: 81-87
Announcement Date:
Nov 01, 1985

Citation Formats

Vaczi, L, Fodor, M, Milch, H, and Rethy, A. Studies on the mercuric chloride resistance of Staphylococcus aureus. Hungary: N. p., 1962. Web.
Vaczi, L, Fodor, M, Milch, H, & Rethy, A. Studies on the mercuric chloride resistance of Staphylococcus aureus. Hungary.
Vaczi, L, Fodor, M, Milch, H, and Rethy, A. 1962. "Studies on the mercuric chloride resistance of Staphylococcus aureus." Hungary.
@misc{etde_5017592,
title = {Studies on the mercuric chloride resistance of Staphylococcus aureus}
author = {Vaczi, L, Fodor, M, Milch, H, and Rethy, A}
abstractNote = {Among 409 pathogenic Staph. aureus strains 34% have been found to be sensitive, and 66% resistant, to mercuric chloride. The incidence of mercuric chloride resistant cultures among antibiotic sensitive staphylococci was 20%; among strains resistant to penicillin or to more than one antibiotic, 70%. Mercuric chloride resistant organisms occurred chiefly among phage group I and untypable strains; they were especially common among the so called epidemic strains of phage group I, and among cultures resistant to 4-6 antibiotics. In mercuric chloride sensitivity a thirtyfold, in merthiolate sensitivity only a two-fold difference has been revealed among the strains. The sulfydryl group content of mercuric chloride resistant organisms was only 1 1/2 times higher than that of sensitive bacteria. As to p-chlor mercuric benzoate binding capacity, a twofold difference was found between mercuric chloride sensitive and resistant staphylococci. The differences in the mercuric chloride resistance of various staphylococcal strains might be due to differences in the chemical structure of the cell surface. 9 references, 1 figure, 6 tables.}
journal = []
volume = {9:1}
journal type = {AC}
place = {Hungary}
year = {1962}
month = {Jan}
}