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THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD

Abstract

Case histories of two patients treated with colloidal radiogold for diffuse reticulum cell sarcoma are presented. Further analysis of the method is suggested by the unusually long survival time of one of the patients. It was concluded that, although external radiotherapy remains the treatment of choice in localized reticulum cell sarcoma, intravenous colloidal radiogold may be a useful agent in lymphosarcomas with diffuse minute neoplastic liver and spleen involvements. Intravenous colloidal radiogold can produce bone marrow depression and thrombocytopenia which can lead to death. This factor tends to argue against therapeutic use of the agent. It is suggested that no more than 50 mC Au/sup 198/ intravenously should be used for treatment of this disease. (R.M.G.)
Publication Date:
Jun 15, 1963
Product Type:
Conference
Report Number:
CONF-164-7
Reference Number:
NSA-18-003669
Resource Relation:
Conference: Society of Nuclear Medicine 10th Annual Meeting, Montreal, Quebec (Canada), 26-29 Jun 1963
Subject:
BIOLOGY AND MEDICINE; BLOOD CELLS; BONE MARROW; CANCER; COLLOIDS; CONFERENCE; GOLD 198; LIVER; LYMPHOSARCOMAS; MAN; PLATELETS; QUANTITY RATIO; RADIATION DOSES; RADIATION EFFECTS; RADIATION INJURIES; RADIOTHERAPY; SARCOMAS; SPLEEN; TUMORS
Sponsoring Organizations:
Sponsor not identified
OSTI ID:
4878068
Research Organizations:
Univ. of Rochester Medical Center, NY (United States); Univ. of Oklahoma Medical Center, Oklahoma City, OK (United States)
Country of Origin:
United States
Language:
English
Submitting Site:
DTIE
Size:
Pages: 21
Announcement Date:
Sep 07, 2013

Citation Formats

Rubin, Philip, and Levitt, Seymour H. THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD. United States: N. p., 1963. Web.
Rubin, Philip, & Levitt, Seymour H. THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD. United States.
Rubin, Philip, and Levitt, Seymour H. 1963. "THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD." United States.
@misc{etde_4878068,
title = {THE RESPONSE OF DISSEMINATED RETICULUM CELL SARCOMA TO THE INTRAVENOUS INJECTION OF COLLOIDAL RADIOACTIVE GOLD}
author = {Rubin, Philip, and Levitt, Seymour H.}
abstractNote = {Case histories of two patients treated with colloidal radiogold for diffuse reticulum cell sarcoma are presented. Further analysis of the method is suggested by the unusually long survival time of one of the patients. It was concluded that, although external radiotherapy remains the treatment of choice in localized reticulum cell sarcoma, intravenous colloidal radiogold may be a useful agent in lymphosarcomas with diffuse minute neoplastic liver and spleen involvements. Intravenous colloidal radiogold can produce bone marrow depression and thrombocytopenia which can lead to death. This factor tends to argue against therapeutic use of the agent. It is suggested that no more than 50 mC Au/sup 198/ intravenously should be used for treatment of this disease. (R.M.G.)}
place = {United States}
year = {1963}
month = {Jun}
}