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Human calf muscular metabolism study with a home-made ergometer using 31P NMR spectroscopy

Abstract

Phosphorus-31 NMR measurements were performed to examine the variations in the concentration of phosphate metabolites in calf muscle during exercise. Therefore, volunteers, installed in the supine position, were asked to push repetitively on the pedal of a home-made ergometer. The produced work and the changes in phosphorus containing metabolites were measured continuously. Correlations were made between the inorganic phosphate/phosphocreatine ratio and the cumulative work and between the intracellular pH and the cumulative work. The exercise protocol could be changed interactively with respect to the imposed initial pressure, the maximum pressure, the pressure increase per level and the time a certain level was held. The whole experiment could be graphically followed on-line. In the first stadium, the in vitro reproducibility of the ergometer was tested for different protocols. These tests revealed that, though the deviation in produced work was markedly the highest at high working pressures, the relative error never exceeded 3%. Consequently, the ex vitro reproducibility of the data was examined with the equipment placed in the scanner. Generally, same conclusions could be derived. In a next stage, the work will be synchronized with the biochemical data. Extreme precautions will be taken to examine each volunteer every time under the  More>>
Authors:
Peynsaert, J; Achten, E; Claeys, E; [1]  Rousseaux, M [2] 
  1. Ghent University Hospital (Belgium)
  2. Ghent University Hospital (Belgium). Dept. of Sport Medicine
Publication Date:
Dec 01, 1995
Product Type:
Conference
Report Number:
INIS-BE-0001; CONF-951246-
Reference Number:
SCA: 550603; PA: AIX-28:034238; EDB-97:069780; SN: 97001775007
Resource Relation:
Conference: 11. annual symposium of the Belgian Association of Hospital Physicists: conformal radiotherapy - physics, treatment planning and verification, Ghent (Belgium), 8-9 Dec 1995; Other Information: PBD: Dec 1995; Related Information: Is Part Of Conformal Radiotherapy: Physics, Treatment Planning and Verification. Proceedings book; De Wagter, C. [ed.]; PB: 273 p.
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; NMR IMAGING; PHOSPHATES; METABOLITES; BEAM OPTICS; BIOMEDICAL RADIOGRAPHY; COLLIMATORS; CONFORMAL MAPPING; DOSIMETRY; IMAGE PROCESSING; IMAGE SCANNERS; ISODOSE CURVES; NEOPLASMS; PHOSPHORUS 31
OSTI ID:
464333
Research Organizations:
Ghent Rijksuniversiteit (Belgium). Kliniek voor Radiotherapie en Kerngeneeskunde
Country of Origin:
Belgium
Language:
English
Other Identifying Numbers:
Other: ON: DE97622340; TRN: BE9700038034238
Availability:
INIS; OSTI as DE97622340
Submitting Site:
BEN
Size:
pp. 19
Announcement Date:
May 13, 1997

Citation Formats

Peynsaert, J, Achten, E, Claeys, E, and Rousseaux, M. Human calf muscular metabolism study with a home-made ergometer using 31P NMR spectroscopy. Belgium: N. p., 1995. Web.
Peynsaert, J, Achten, E, Claeys, E, & Rousseaux, M. Human calf muscular metabolism study with a home-made ergometer using 31P NMR spectroscopy. Belgium.
Peynsaert, J, Achten, E, Claeys, E, and Rousseaux, M. 1995. "Human calf muscular metabolism study with a home-made ergometer using 31P NMR spectroscopy." Belgium.
@misc{etde_464333,
title = {Human calf muscular metabolism study with a home-made ergometer using 31P NMR spectroscopy}
author = {Peynsaert, J, Achten, E, Claeys, E, and Rousseaux, M}
abstractNote = {Phosphorus-31 NMR measurements were performed to examine the variations in the concentration of phosphate metabolites in calf muscle during exercise. Therefore, volunteers, installed in the supine position, were asked to push repetitively on the pedal of a home-made ergometer. The produced work and the changes in phosphorus containing metabolites were measured continuously. Correlations were made between the inorganic phosphate/phosphocreatine ratio and the cumulative work and between the intracellular pH and the cumulative work. The exercise protocol could be changed interactively with respect to the imposed initial pressure, the maximum pressure, the pressure increase per level and the time a certain level was held. The whole experiment could be graphically followed on-line. In the first stadium, the in vitro reproducibility of the ergometer was tested for different protocols. These tests revealed that, though the deviation in produced work was markedly the highest at high working pressures, the relative error never exceeded 3%. Consequently, the ex vitro reproducibility of the data was examined with the equipment placed in the scanner. Generally, same conclusions could be derived. In a next stage, the work will be synchronized with the biochemical data. Extreme precautions will be taken to examine each volunteer every time under the same physical and psychological conditions.}
place = {Belgium}
year = {1995}
month = {Dec}
}