You need JavaScript to view this

Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI)

Abstract

As co-monomers are found to polymerize by radiation, they are eligible for constructing a three dimensional dosimeter. Another kind of three dimensional dosimeter, based on the radiation sensitivity of the ferrous ions in a Fricke solution, was tested in a previous study. However, a major problem that occurs in this kind of gel dosimeters is the diffusion of the ferric and ferrous ions. The co-monomer gels are more stable. The degree of polymerisation is visualized with a clinical MRI system. Acrylamide and N,N-methylene-bis-acrylamide are dissolved in a gel composed of gelatin and water. By irradiation the co-monomers are polymerized to polyacrylamide. The gel is casted in humanoid forms. As such, a simulation of the irradiation of the patient can be performed. Magnetic resonance relaxivity images of the irradiated gel display the irradiation dose. The images of the gel are fused with the radiological images of the patient. Quantitation of the dose response of the co-monomer gel is obtained through calibration by test tubes.
Authors:
De Deene, Y; De Wagter, C; Van Duyse, B; Achten, E; De Neve, W; [1]  De Poorter, J [2] 
  1. Ghent Rijksuniversiteit (Belgium). Kliniek voor Radiotherapie en Kerngeneeskunde
  2. Ghent Univ. (Belgium). Dept. of Magnetic Resonance
Publication Date:
Dec 01, 1995
Product Type:
Conference
Report Number:
INIS-BE-0001; CONF-951246-
Reference Number:
SCA: 550603; PA: AIX-28:034231; EDB-97:069806; SN: 97001775000
Resource Relation:
Conference: 11. annual symposium of the Belgian Association of Hospital Physicists: conformal radiotherapy - physics, treatment planning and verification, Ghent (Belgium), 8-9 Dec 1995; Other Information: PBD: Dec 1995; Related Information: Is Part Of Conformal Radiotherapy: Physics, Treatment Planning and Verification. Proceedings book; De Wagter, C. [ed.]; PB: 273 p.
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; RADIOTHERAPY; DOSIMETRY; ACRYLAMIDE; BEAM OPTICS; BIOMEDICAL RADIOGRAPHY; COLLIMATORS; CONFORMAL MAPPING; DELAYED RADIATION EFFECTS; IMAGE PROCESSING; IMAGE SCANNERS; ISODOSE CURVES; MONOMERS; NEOPLASMS; QUALITY ASSURANCE
OSTI ID:
464326
Research Organizations:
Ghent Rijksuniversiteit (Belgium). Kliniek voor Radiotherapie en Kerngeneeskunde
Country of Origin:
Belgium
Language:
English
Other Identifying Numbers:
Other: ON: DE97622340; TRN: BE9700031034231
Availability:
INIS; OSTI as DE97622340
Submitting Site:
BEN
Size:
pp. 193-208
Announcement Date:

Citation Formats

De Deene, Y, De Wagter, C, Van Duyse, B, Achten, E, De Neve, W, and De Poorter, J. Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI). Belgium: N. p., 1995. Web.
De Deene, Y, De Wagter, C, Van Duyse, B, Achten, E, De Neve, W, & De Poorter, J. Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI). Belgium.
De Deene, Y, De Wagter, C, Van Duyse, B, Achten, E, De Neve, W, and De Poorter, J. 1995. "Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI)." Belgium.
@misc{etde_464326,
title = {Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI)}
author = {De Deene, Y, De Wagter, C, Van Duyse, B, Achten, E, De Neve, W, and De Poorter, J}
abstractNote = {As co-monomers are found to polymerize by radiation, they are eligible for constructing a three dimensional dosimeter. Another kind of three dimensional dosimeter, based on the radiation sensitivity of the ferrous ions in a Fricke solution, was tested in a previous study. However, a major problem that occurs in this kind of gel dosimeters is the diffusion of the ferric and ferrous ions. The co-monomer gels are more stable. The degree of polymerisation is visualized with a clinical MRI system. Acrylamide and N,N-methylene-bis-acrylamide are dissolved in a gel composed of gelatin and water. By irradiation the co-monomers are polymerized to polyacrylamide. The gel is casted in humanoid forms. As such, a simulation of the irradiation of the patient can be performed. Magnetic resonance relaxivity images of the irradiated gel display the irradiation dose. The images of the gel are fused with the radiological images of the patient. Quantitation of the dose response of the co-monomer gel is obtained through calibration by test tubes.}
place = {Belgium}
year = {1995}
month = {Dec}
}