Abstract
The variation in treatment portals for elective radiotherapy of the neck, and the three-dimensional dosimetric consequences of this variation was assessed. Therefore, 16 experienced radiation oncologists from all major head and neck cooperative groups in the Netherlands (n=11) were asked to define RT-portals on a lateral and/or AP simulation film, for (routine) elective neck irradiation for a T2 tumor of the mobile tongue and a T3 tumor of the supraglottic larynx. Treatment portals were compared and evaluated using a three-dimensional treatment planning system and CT data with contoured critical structures and target volume. The CT-defined clinical target volume was mutually agreed upon by ENT-surgeons and radiation oncologists. Large differences were seen in treated volume (a factor of five). In addition, due to the variation in the cranial boundary of the RT-portals, the estimated NTCP varied considerably (0-50%). Moreover, several of the RT-portals did not adequately cover the CT-defined target volume. Even amongst experienced head and neck radiation oncologists, little agreement was observed with respect to treatment technique and size of the treatment portals in case of elective neck irradiation. This results in a considerable variation in treated volume. As a consequence, a large difference exists in the anticipated probability of
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Van Dieren, E B;
[1]
Nowak, P J.C.M.;
Van Soernsen de Koste, J.R.;
Van Est, H;
Heijmen, B J.M.;
Levendag, P C
- Integraal Kankercentrum, Rotterdam (Netherlands)
Citation Formats
Van Dieren, E B, Nowak, P J.C.M., Van Soernsen de Koste, J.R., Van Est, H, Heijmen, B J.M., and Levendag, P C.
A nationwide Dutch study regarding treatment portals for elective neck irradiation.
Belgium: N. p.,
1995.
Web.
Van Dieren, E B, Nowak, P J.C.M., Van Soernsen de Koste, J.R., Van Est, H, Heijmen, B J.M., & Levendag, P C.
A nationwide Dutch study regarding treatment portals for elective neck irradiation.
Belgium.
Van Dieren, E B, Nowak, P J.C.M., Van Soernsen de Koste, J.R., Van Est, H, Heijmen, B J.M., and Levendag, P C.
1995.
"A nationwide Dutch study regarding treatment portals for elective neck irradiation."
Belgium.
@misc{etde_464309,
title = {A nationwide Dutch study regarding treatment portals for elective neck irradiation}
author = {Van Dieren, E B, Nowak, P J.C.M., Van Soernsen de Koste, J.R., Van Est, H, Heijmen, B J.M., and Levendag, P C}
abstractNote = {The variation in treatment portals for elective radiotherapy of the neck, and the three-dimensional dosimetric consequences of this variation was assessed. Therefore, 16 experienced radiation oncologists from all major head and neck cooperative groups in the Netherlands (n=11) were asked to define RT-portals on a lateral and/or AP simulation film, for (routine) elective neck irradiation for a T2 tumor of the mobile tongue and a T3 tumor of the supraglottic larynx. Treatment portals were compared and evaluated using a three-dimensional treatment planning system and CT data with contoured critical structures and target volume. The CT-defined clinical target volume was mutually agreed upon by ENT-surgeons and radiation oncologists. Large differences were seen in treated volume (a factor of five). In addition, due to the variation in the cranial boundary of the RT-portals, the estimated NTCP varied considerably (0-50%). Moreover, several of the RT-portals did not adequately cover the CT-defined target volume. Even amongst experienced head and neck radiation oncologists, little agreement was observed with respect to treatment technique and size of the treatment portals in case of elective neck irradiation. This results in a considerable variation in treated volume. As a consequence, a large difference exists in the anticipated probability of normal tissue complication, and possibly in tumor control probability. Therefore, a definition of target volume and, consequently, a standardization of elective neck portals in mandatory. This is even more important if the primary tumor and clinically node-negative neck are to be treated by 3D conformal RT using multiple CT-slices for target delineation and positioning of BEV blocks in order to spare the normal tissue function with maximum tumor control probability.}
place = {Belgium}
year = {1995}
month = {Dec}
}
title = {A nationwide Dutch study regarding treatment portals for elective neck irradiation}
author = {Van Dieren, E B, Nowak, P J.C.M., Van Soernsen de Koste, J.R., Van Est, H, Heijmen, B J.M., and Levendag, P C}
abstractNote = {The variation in treatment portals for elective radiotherapy of the neck, and the three-dimensional dosimetric consequences of this variation was assessed. Therefore, 16 experienced radiation oncologists from all major head and neck cooperative groups in the Netherlands (n=11) were asked to define RT-portals on a lateral and/or AP simulation film, for (routine) elective neck irradiation for a T2 tumor of the mobile tongue and a T3 tumor of the supraglottic larynx. Treatment portals were compared and evaluated using a three-dimensional treatment planning system and CT data with contoured critical structures and target volume. The CT-defined clinical target volume was mutually agreed upon by ENT-surgeons and radiation oncologists. Large differences were seen in treated volume (a factor of five). In addition, due to the variation in the cranial boundary of the RT-portals, the estimated NTCP varied considerably (0-50%). Moreover, several of the RT-portals did not adequately cover the CT-defined target volume. Even amongst experienced head and neck radiation oncologists, little agreement was observed with respect to treatment technique and size of the treatment portals in case of elective neck irradiation. This results in a considerable variation in treated volume. As a consequence, a large difference exists in the anticipated probability of normal tissue complication, and possibly in tumor control probability. Therefore, a definition of target volume and, consequently, a standardization of elective neck portals in mandatory. This is even more important if the primary tumor and clinically node-negative neck are to be treated by 3D conformal RT using multiple CT-slices for target delineation and positioning of BEV blocks in order to spare the normal tissue function with maximum tumor control probability.}
place = {Belgium}
year = {1995}
month = {Dec}
}