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Comparative study between in Vivo and Vitro radionuclide technique in measurement of Glomerular filtration rate

Abstract

Fifty patients were referred to nuclear medicine department in NEMROCK center for measurement of glomerular filtration rate (GFR). The group included 34 males and 16 females with a mean age of 38.3 {+-} 10.7 years. Estimation of GFR was done using 111-185 mBq of {sup 99m} Tc-DTPA with data collected on 128 x 128 matrix on IDAC computer every 15 seconds with calculation of renal uptake and GFR applying Gates method. 72 hours, a dose 3.7 mBq of {sup 51} Cr-EDTA with 2 blood samples taken at 120, 240 minutes with estimation of plasma clearance using Russel et al., method (1985). The mean clearance of {sup 51} Cr-EDTA was 79.61{+-}22.4 ml/min compared to 84.34{+-}26.3 ml/min. Using direct scintigraphic method with positive correlation using regression analysis (r=0.96). Also, both {sup 51} Cr-EDTA and in vivo {sup 99m} Tc-DTPA were positively correlated with creatinine clearance (r=0.87 and 0.91 respectively). A modified regression formulas was used for correction of the results of {sup 99m} Tc-DTPA values GFR ({sup 99m}Tc-DTPA) x 0.81 + 11 {+-} 6.4 ml/min. 4 figs., 1 tab.
Authors:
Ziada, G; Moustafa, H; Elhaddad, SH; Taalab, KH [1] 
  1. Nuclear medicine department, Faculty of medicine, Cairo university, Cairo, (Egypt)
Publication Date:
Oct 01, 1995
Product Type:
Miscellaneous
Report Number:
INIS-EG-001; CONF-9411323-
Reference Number:
SCA: 550604; PA: AIX-28:030563; EDB-97:057831; SN: 97001765229
Resource Relation:
Conference: 2. Arab conference on the peaceful uses of atomic energy, Cairo (Egypt), 5-9 Nov 1994; Other Information: PBD: Oct 1995; Related Information: Is Part Of Proceedings of the second Arab conference on the peaceful uses of atomic energy. Part II: A and B; Barakat, M.F.; El-Mashri, S.M. [eds.]; PB: 1199 p.
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; RENAL CLEARANCE; EGYPTIAN ARAB REPUBLIC; FILTRATION; TRACER TECHNIQUES; COMPUTER CALCULATIONS; CORIUM; EVALUATED DATA; EXPERIMENTAL DATA; NUCLEAR MEDICINE; PATIENTS; RADIOISOTOPES; TECHNETIUM 99
OSTI ID:
456031
Research Organizations:
Atomic Energy Authority, Cairo (Egypt); Arab Atomic Energy Agency (AAEA), Tunis (Tunisia); Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo (Egypt)
Country of Origin:
Egypt
Language:
English
Other Identifying Numbers:
Other: ON: DE97620040; ISBN 9973-9927-3-3; TRN: EG9601666030563
Availability:
INIS; OSTI as DE97620040
Submitting Site:
INIS
Size:
pp. 477
Announcement Date:
Jan 21, 2004

Citation Formats

Ziada, G, Moustafa, H, Elhaddad, SH, and Taalab, KH. Comparative study between in Vivo and Vitro radionuclide technique in measurement of Glomerular filtration rate. Egypt: N. p., 1995. Web.
Ziada, G, Moustafa, H, Elhaddad, SH, & Taalab, KH. Comparative study between in Vivo and Vitro radionuclide technique in measurement of Glomerular filtration rate. Egypt.
Ziada, G, Moustafa, H, Elhaddad, SH, and Taalab, KH. 1995. "Comparative study between in Vivo and Vitro radionuclide technique in measurement of Glomerular filtration rate." Egypt.
@misc{etde_456031,
title = {Comparative study between in Vivo and Vitro radionuclide technique in measurement of Glomerular filtration rate}
author = {Ziada, G, Moustafa, H, Elhaddad, SH, and Taalab, KH}
abstractNote = {Fifty patients were referred to nuclear medicine department in NEMROCK center for measurement of glomerular filtration rate (GFR). The group included 34 males and 16 females with a mean age of 38.3 {+-} 10.7 years. Estimation of GFR was done using 111-185 mBq of {sup 99m} Tc-DTPA with data collected on 128 x 128 matrix on IDAC computer every 15 seconds with calculation of renal uptake and GFR applying Gates method. 72 hours, a dose 3.7 mBq of {sup 51} Cr-EDTA with 2 blood samples taken at 120, 240 minutes with estimation of plasma clearance using Russel et al., method (1985). The mean clearance of {sup 51} Cr-EDTA was 79.61{+-}22.4 ml/min compared to 84.34{+-}26.3 ml/min. Using direct scintigraphic method with positive correlation using regression analysis (r=0.96). Also, both {sup 51} Cr-EDTA and in vivo {sup 99m} Tc-DTPA were positively correlated with creatinine clearance (r=0.87 and 0.91 respectively). A modified regression formulas was used for correction of the results of {sup 99m} Tc-DTPA values GFR ({sup 99m}Tc-DTPA) x 0.81 + 11 {+-} 6.4 ml/min. 4 figs., 1 tab.}
place = {Egypt}
year = {1995}
month = {Oct}
}