Abstract
In this work we studied the effect of radiotherapy on normal cells in patients with cervix tumors treated only by gamma rays. In our laboratory, after lymphocytes separation, we tested the proliferation system of these cells against the phytohemagglutinin and the concanavalin a antigens; at the same time we tested their sensitivity to lys the erythroid tumor cells line K 562. According to the clinical stage of disease the 25 patients studied were divided in two groups; group I composed of 14 patients at stage I and II proximal, received 50 Gy from a cesium 137 source, in intrauterine and in continuous treatment during 4 days. The second group composed of 11 patients at stage II distal and III, received 50 Gy from a cobalt-60 source in extra uterine, the treatment is fractioned in 3 to 5 times per week, at each time the patient received 1,5 - 3 Gy. To compare with their immunological status before treatment, until 1 month after total dose received, all of our patients lost transitory their capacity to prolifere in vitro. Although the capacity to lys the tumor cells is diminished in cancer patients, the drop of this activity is principally. The selective recuperation
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Oueslati, R;
Kdous, CH;
Chouikha, M;
[1]
Maalej, M;
Kochbati, N
[2]
- Lab. Immunology, Hopital de Tunis, (Tunisia)
- Service Radiotherapy, Institut Salah Azeiz, (Tunisia)
Citation Formats
Oueslati, R, Kdous, CH, Chouikha, M, Maalej, M, and Kochbati, N.
Sensitivity of T lymphocytes to gamma rays in patients with cervix tumor.
Egypt: N. p.,
1995.
Web.
Oueslati, R, Kdous, CH, Chouikha, M, Maalej, M, & Kochbati, N.
Sensitivity of T lymphocytes to gamma rays in patients with cervix tumor.
Egypt.
Oueslati, R, Kdous, CH, Chouikha, M, Maalej, M, and Kochbati, N.
1995.
"Sensitivity of T lymphocytes to gamma rays in patients with cervix tumor."
Egypt.
@misc{etde_456029,
title = {Sensitivity of T lymphocytes to gamma rays in patients with cervix tumor}
author = {Oueslati, R, Kdous, CH, Chouikha, M, Maalej, M, and Kochbati, N}
abstractNote = {In this work we studied the effect of radiotherapy on normal cells in patients with cervix tumors treated only by gamma rays. In our laboratory, after lymphocytes separation, we tested the proliferation system of these cells against the phytohemagglutinin and the concanavalin a antigens; at the same time we tested their sensitivity to lys the erythroid tumor cells line K 562. According to the clinical stage of disease the 25 patients studied were divided in two groups; group I composed of 14 patients at stage I and II proximal, received 50 Gy from a cesium 137 source, in intrauterine and in continuous treatment during 4 days. The second group composed of 11 patients at stage II distal and III, received 50 Gy from a cobalt-60 source in extra uterine, the treatment is fractioned in 3 to 5 times per week, at each time the patient received 1,5 - 3 Gy. To compare with their immunological status before treatment, until 1 month after total dose received, all of our patients lost transitory their capacity to prolifere in vitro. Although the capacity to lys the tumor cells is diminished in cancer patients, the drop of this activity is principally. The selective recuperation of T lymphocytes stimulated by concanavalin A is also observed. 3 figs., 2 tabs.}
place = {Egypt}
year = {1995}
month = {Oct}
}
title = {Sensitivity of T lymphocytes to gamma rays in patients with cervix tumor}
author = {Oueslati, R, Kdous, CH, Chouikha, M, Maalej, M, and Kochbati, N}
abstractNote = {In this work we studied the effect of radiotherapy on normal cells in patients with cervix tumors treated only by gamma rays. In our laboratory, after lymphocytes separation, we tested the proliferation system of these cells against the phytohemagglutinin and the concanavalin a antigens; at the same time we tested their sensitivity to lys the erythroid tumor cells line K 562. According to the clinical stage of disease the 25 patients studied were divided in two groups; group I composed of 14 patients at stage I and II proximal, received 50 Gy from a cesium 137 source, in intrauterine and in continuous treatment during 4 days. The second group composed of 11 patients at stage II distal and III, received 50 Gy from a cobalt-60 source in extra uterine, the treatment is fractioned in 3 to 5 times per week, at each time the patient received 1,5 - 3 Gy. To compare with their immunological status before treatment, until 1 month after total dose received, all of our patients lost transitory their capacity to prolifere in vitro. Although the capacity to lys the tumor cells is diminished in cancer patients, the drop of this activity is principally. The selective recuperation of T lymphocytes stimulated by concanavalin A is also observed. 3 figs., 2 tabs.}
place = {Egypt}
year = {1995}
month = {Oct}
}