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The value of serial quantitative technetium-99 m methylene diphosphonate in assessment of the response of metastatic skeletal lesions to different types of treatment modalities.

Abstract

The study included 95 patients having metastatic bone lesions, subjected to serial quantitative skeletal scintigraphy before and after treatment every 3 months for 6 months. To study the fate of metastatic bone lesions the effect of different treatment modalities, an objective index was used. This index was introduced in 1985 by Israel et al. (1), and was designated TF. A significant drop in TF ratio was observed 6 months following therapy in the groups who received combined localized radiotherapy together with systemic therapy and those who received half body irradiation. In contrast, a marked increase in TF ratio was observed in the patients who did not receive any specific treatment. The response of metastatic skeletal lesions was nearly similar whatever the site of involvement whether in the spine, flat or long bones except for an initial response in the long bones with drop of TF ratio after localized radiotherapy. 1 fig., 3 tabs.
Authors:
Moustafa, H; Elhaddad, SH; Ziada, G; Fawzi, A [1] 
  1. Nuclear medicine department, faculty of medicine, cairo university, Cairo, (Egypt)
Publication Date:
Oct 01, 1995
Product Type:
Miscellaneous
Report Number:
INIS-EG-001; CONF-9411323-
Reference Number:
SCA: 560161; PA: AIX-28:030197; EDB-97:058079; SN: 97001765024
Resource Relation:
Conference: 2. Arab conference on the peaceful uses of atomic energy, Cairo (Egypt), 5-9 Nov 1994; Other Information: PBD: Oct 1995; Related Information: Is Part Of Proceedings of the second Arab conference on the peaceful uses of atomic energy. Part II: A and B; Barakat, M.F.; El-Mashri, S.M. [eds.]; PB: 1199 p.
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; SKELETON; TECHNETIUM 99; WHOLE-BODY IRRADIATION; CHARGES; EXPERIMENTAL DATA; PATIENTS; RADIOTHERAPY; SCINTISCANNING; VERTEBRATES
OSTI ID:
455951
Research Organizations:
Atomic Energy Authority, Cairo (Egypt); Arab Atomic Energy Agency (AAEA), Tunis (Tunisia); Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo (Egypt)
Country of Origin:
Egypt
Language:
English
Other Identifying Numbers:
Other: ON: DE97620040; ISBN 9973-9927-3-3; TRN: EG9601672030197
Availability:
INIS; OSTI as DE97620040
Submitting Site:
INIS
Size:
pp. 537
Announcement Date:
Jan 21, 2004

Citation Formats

Moustafa, H, Elhaddad, SH, Ziada, G, and Fawzi, A. The value of serial quantitative technetium-99 m methylene diphosphonate in assessment of the response of metastatic skeletal lesions to different types of treatment modalities.. Egypt: N. p., 1995. Web.
Moustafa, H, Elhaddad, SH, Ziada, G, & Fawzi, A. The value of serial quantitative technetium-99 m methylene diphosphonate in assessment of the response of metastatic skeletal lesions to different types of treatment modalities.. Egypt.
Moustafa, H, Elhaddad, SH, Ziada, G, and Fawzi, A. 1995. "The value of serial quantitative technetium-99 m methylene diphosphonate in assessment of the response of metastatic skeletal lesions to different types of treatment modalities." Egypt.
@misc{etde_455951,
title = {The value of serial quantitative technetium-99 m methylene diphosphonate in assessment of the response of metastatic skeletal lesions to different types of treatment modalities.}
author = {Moustafa, H, Elhaddad, SH, Ziada, G, and Fawzi, A}
abstractNote = {The study included 95 patients having metastatic bone lesions, subjected to serial quantitative skeletal scintigraphy before and after treatment every 3 months for 6 months. To study the fate of metastatic bone lesions the effect of different treatment modalities, an objective index was used. This index was introduced in 1985 by Israel et al. (1), and was designated TF. A significant drop in TF ratio was observed 6 months following therapy in the groups who received combined localized radiotherapy together with systemic therapy and those who received half body irradiation. In contrast, a marked increase in TF ratio was observed in the patients who did not receive any specific treatment. The response of metastatic skeletal lesions was nearly similar whatever the site of involvement whether in the spine, flat or long bones except for an initial response in the long bones with drop of TF ratio after localized radiotherapy. 1 fig., 3 tabs.}
place = {Egypt}
year = {1995}
month = {Oct}
}