Male albino rats were exposed to gamma irradiation alone or after either oral daily administration of 50 or 100 mg kelthane for 3 successive days; or daily administration of 200 mg kelthane mixed with food per kg body weight for 3,6 and 12 weeks. Relative spleen weight and certain hematological values were determined. Significant decrease could be estimated in relative spleen weight due to exposure only to gamma irradiation significant increase was recorded due to treatment with 50 and 100 mg kelthane. The data obtained on hematological levels revealed insignificant changes in erythrocyte counts and hemoglobin concentration due to exposure to gamma irradiation and/.or kelthane treatment. Significant decrease was recorded in hematocrit value either for successive 30 days or due exposure to gamma irradiation after treatment with kelthane for short and long term periods. Leucocyte counts showed significant decrease for all animals groups. 2 tabs.
abdel-Hamid, F M;  Roushdy, H M;  Girgis, R B; Abu-Ghadir, A R 
- Radioisotope Department, Nuclear Research Center, Radiation Biology, cairo (Egypt)
- Department, National Center for Radiation Reasrch and Technology, Cairo (Egypt)
- Atomic Energy Authority, and Zoology Department, Faculty of Science, Cairo University, Cairo (Egypt)