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Physiological basis of iodine prophylaxis in case of a nuclear accident

Abstract

The uptake of radioactive iodine may be prevented in nearly 100% if the stable iodine will be in sufficiently large quantity before the release radioactive isotopes to the atmosphere. It may also, at least partially reduce the thyroid uptake of radioactive isotopes even if given later. The quantity of stable iodine recommended differs, however most of the data indicate that the doses of 100 mg given to the adult persons might nearly totally block the thyroid iodine uptake. The prophylactic action carried out in Poland after the Chernobyl disaster when about 12 million children and 6 million adults received the stable iodine allowed to collect well documented data in this matter. It was stated that 70 mg of stable iodine is blocking the thyroid uptake with the mean of 82% after 24 hours, 39% after 48 hours and only 26% after 72 hours. Therefore it seems that the blocking doses (which may be even less than 70 mg) should be given every 24 hours for a few days hoping that the most serious danger of contamination with radioactive iodine will pass. 14 refs, 4 figs.
Authors:
Gembicki, M [1] 
  1. University School of Medical Sciences, Poznan (Poland). Dept. of Endocrinology
Publication Date:
Aug 01, 1996
Product Type:
Conference
Report Number:
IAEA-TECDOC-893; CONF-9405381-
Reference Number:
SCA: 560161; 570100; PA: AIX-28:017697; EDB-97:030055; SN: 97001735631
Resource Relation:
Conference: International symposium on radiodosimetry and preventive measures in the event of a nuclear accident, Cracow (Poland), 26-28 May 1994; Other Information: PBD: Aug 1996; Related Information: Is Part Of Radiodosimetry and preventive measures in the event of a nuclear accident. Proceedings of an international symposium; PB: 119 p.
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; 57 HEALTH AND SAFETY; IODINE 131; BIOLOGICAL LOCALIZATION; THYROID; BIOLOGICAL RADIATION EFFECTS; CARCINOGENESIS; CHERNOBYLSK-4 REACTOR; CHILDREN; HYPOTHYROIDISM; PHYSIOLOGY; RADIATION DOSES; REACTOR ACCIDENTS; UPTAKE
OSTI ID:
429896
Research Organizations:
International Atomic Energy Agency, Vienna (Austria); Polish Society of Nuclear Medicine (Poland)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1011-4289; Other: ON: DE97614107; TRN: XA9643032017697
Availability:
INIS; OSTI as DE97614107
Submitting Site:
INIS
Size:
pp. 87-100
Announcement Date:
Feb 24, 1997

Citation Formats

Gembicki, M. Physiological basis of iodine prophylaxis in case of a nuclear accident. IAEA: N. p., 1996. Web.
Gembicki, M. Physiological basis of iodine prophylaxis in case of a nuclear accident. IAEA.
Gembicki, M. 1996. "Physiological basis of iodine prophylaxis in case of a nuclear accident." IAEA.
@misc{etde_429896,
title = {Physiological basis of iodine prophylaxis in case of a nuclear accident}
author = {Gembicki, M}
abstractNote = {The uptake of radioactive iodine may be prevented in nearly 100% if the stable iodine will be in sufficiently large quantity before the release radioactive isotopes to the atmosphere. It may also, at least partially reduce the thyroid uptake of radioactive isotopes even if given later. The quantity of stable iodine recommended differs, however most of the data indicate that the doses of 100 mg given to the adult persons might nearly totally block the thyroid iodine uptake. The prophylactic action carried out in Poland after the Chernobyl disaster when about 12 million children and 6 million adults received the stable iodine allowed to collect well documented data in this matter. It was stated that 70 mg of stable iodine is blocking the thyroid uptake with the mean of 82% after 24 hours, 39% after 48 hours and only 26% after 72 hours. Therefore it seems that the blocking doses (which may be even less than 70 mg) should be given every 24 hours for a few days hoping that the most serious danger of contamination with radioactive iodine will pass. 14 refs, 4 figs.}
place = {IAEA}
year = {1996}
month = {Aug}
}