Abstract
The malnutrition is prevalent and is a major problem among Bolivian children. It is caused by several interacting factors: (1) inadequate protein energy intake due to low socio-economic status; (ii) exposure to acute, repeated and chronic bacterial infections; (iii) exposure to multiple and chronic parasitic infections; (iv) high altitude of the capital, La Paz, 3600 m, with a numerous populations compared to the rest of the country. The research objectives in the first phase are: (i) determination of protein utilization with a non-invasive method using stable isotope tracer among children living at high and low altitude; (ii) determination of protein metabolism among eutrophic children without parasitic or acute bacterial infections at both altitudes; (iii) determination of protein requirement among these children. Two groups of 10 pubertal children, matched for age and sex, of same socio-economic status, eutrophic, without malnutrition, infections or intestinal parasites will be studied; the different status being arrived by anthropometric, nutritional intake, biochemical and pediatrical evaluation. For the metabolic study, stable isotopes L-[1-13C] leucine labelled casein will be used and {sup 13}CO{sub 2} excreted will be measured. All the basic nutritional assessment and VCO{sub 2} measurements will be performed in Bolivia, while the samples of expired gas
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San Miguel Simron, J L;
Berger, J;
Spielvogel, H;
Tellez Castellon, W;
Lujan Medina, C;
Caceres, E;
[1]
Beaufrere, B;
Gachons, P;
Coudert, J
[2]
- Instituto Boliviano de Boliviano de Biologia de Altura, La Paz (Bolivia). Dept. de Nutricion
- Laboratoire de Nutrition Humaine, Clermont-Ferrand (France)
Citation Formats
San Miguel Simron, J L, Berger, J, Spielvogel, H, Tellez Castellon, W, Lujan Medina, C, Caceres, E, Beaufrere, B, Gachons, P, and Coudert, J.
Effect of altitude on the protein metabolism of Bolivian children.
IAEA: N. p.,
1996.
Web.
San Miguel Simron, J L, Berger, J, Spielvogel, H, Tellez Castellon, W, Lujan Medina, C, Caceres, E, Beaufrere, B, Gachons, P, & Coudert, J.
Effect of altitude on the protein metabolism of Bolivian children.
IAEA.
San Miguel Simron, J L, Berger, J, Spielvogel, H, Tellez Castellon, W, Lujan Medina, C, Caceres, E, Beaufrere, B, Gachons, P, and Coudert, J.
1996.
"Effect of altitude on the protein metabolism of Bolivian children."
IAEA.
@misc{etde_424814,
title = {Effect of altitude on the protein metabolism of Bolivian children}
author = {San Miguel Simron, J L, Berger, J, Spielvogel, H, Tellez Castellon, W, Lujan Medina, C, Caceres, E, Beaufrere, B, Gachons, P, and Coudert, J}
abstractNote = {The malnutrition is prevalent and is a major problem among Bolivian children. It is caused by several interacting factors: (1) inadequate protein energy intake due to low socio-economic status; (ii) exposure to acute, repeated and chronic bacterial infections; (iii) exposure to multiple and chronic parasitic infections; (iv) high altitude of the capital, La Paz, 3600 m, with a numerous populations compared to the rest of the country. The research objectives in the first phase are: (i) determination of protein utilization with a non-invasive method using stable isotope tracer among children living at high and low altitude; (ii) determination of protein metabolism among eutrophic children without parasitic or acute bacterial infections at both altitudes; (iii) determination of protein requirement among these children. Two groups of 10 pubertal children, matched for age and sex, of same socio-economic status, eutrophic, without malnutrition, infections or intestinal parasites will be studied; the different status being arrived by anthropometric, nutritional intake, biochemical and pediatrical evaluation. For the metabolic study, stable isotopes L-[1-13C] leucine labelled casein will be used and {sup 13}CO{sub 2} excreted will be measured. All the basic nutritional assessment and VCO{sub 2} measurements will be performed in Bolivia, while the samples of expired gas will be stored in Vacutainers for further analysis by isotope radio mass spectrometer (IRMS), in Clermont-Ferrand, France. The plans for future work is based on the study of the effects of the different variables and their interactions. The following will be evaluated: (i) the socio-economic status; (ii) the bacterial infections: (iii) the parasitic infections; (iv) the altitude. As published by Obert, et al., the socio-economic variable is more connected with the nutritional status than with the altitude. 12 refs, 1 fig., 1 tab.}
place = {IAEA}
year = {1996}
month = {Dec}
}
title = {Effect of altitude on the protein metabolism of Bolivian children}
author = {San Miguel Simron, J L, Berger, J, Spielvogel, H, Tellez Castellon, W, Lujan Medina, C, Caceres, E, Beaufrere, B, Gachons, P, and Coudert, J}
abstractNote = {The malnutrition is prevalent and is a major problem among Bolivian children. It is caused by several interacting factors: (1) inadequate protein energy intake due to low socio-economic status; (ii) exposure to acute, repeated and chronic bacterial infections; (iii) exposure to multiple and chronic parasitic infections; (iv) high altitude of the capital, La Paz, 3600 m, with a numerous populations compared to the rest of the country. The research objectives in the first phase are: (i) determination of protein utilization with a non-invasive method using stable isotope tracer among children living at high and low altitude; (ii) determination of protein metabolism among eutrophic children without parasitic or acute bacterial infections at both altitudes; (iii) determination of protein requirement among these children. Two groups of 10 pubertal children, matched for age and sex, of same socio-economic status, eutrophic, without malnutrition, infections or intestinal parasites will be studied; the different status being arrived by anthropometric, nutritional intake, biochemical and pediatrical evaluation. For the metabolic study, stable isotopes L-[1-13C] leucine labelled casein will be used and {sup 13}CO{sub 2} excreted will be measured. All the basic nutritional assessment and VCO{sub 2} measurements will be performed in Bolivia, while the samples of expired gas will be stored in Vacutainers for further analysis by isotope radio mass spectrometer (IRMS), in Clermont-Ferrand, France. The plans for future work is based on the study of the effects of the different variables and their interactions. The following will be evaluated: (i) the socio-economic status; (ii) the bacterial infections: (iii) the parasitic infections; (iv) the altitude. As published by Obert, et al., the socio-economic variable is more connected with the nutritional status than with the altitude. 12 refs, 1 fig., 1 tab.}
place = {IAEA}
year = {1996}
month = {Dec}
}