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Biological radiation effects of Radon in Drosophila; Efectos biologicos del radon en Drosophila

Abstract

In order to contribute to the knowledge on the effects of radon and its decay products, the aim of this investigation is to study the biological effects of radon using Drosophila melanogaster throught the somatic mutation and recombination test (SMART) and the analysis of some adaptative factors exposing larvaes to controlled radon atmosphers, considering that this insect could be used as biological monitor. Using the somatic mutation test a mutagenic effect was observed proportional to radon concentration, into an interval of 1 {+-} 0.3 to 111 {+-} 7.4 KBq/m{sup 3} equivalent to doses under 0.0106 Gy. The correlation analysis gives a linear (r=0.80) relationship with a positive slope of 0.2217. The same happens when gamma rays are used in the interval of 1 to 20 Gy, given a linear dose-dependent effect (r=0.878) is obtained; nevetheless the slop is smaller (m=0.003) than for radon. Analysing the results of adaptative factors of the nine exposed generations, it was found that probably radon exposition induced dominant lethals during gametogenesis or/and a selection of the more component gamets of the treated individuals in larval state. It was reflected in the significant decrease on fecundity of the generation exposed. Nevertheless the laying eggs had an  More>>
Authors:
Publication Date:
Dec 31, 1995
Product Type:
Thesis/Dissertation
Report Number:
INIS-mf-14684
Reference Number:
SCA: 560162; PA: AIX-28:000826; EDB-97:010377; NTS-97:004598; SN: 97001711388
Resource Relation:
Other Information: TH: Thesis (M. in Sc.).; PBD: 1995
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; DROSOPHILA; BIOLOGICAL RADIATION EFFECTS; RADON 222; ALPHA SOURCES; DIELECTRIC TRACK DETECTORS; EGGS; LARVAE; MUTATION FREQUENCY; PITCHBLENDE; RADIATION INJURIES; RECOMBINANT DNA; SPARK COUNTERS
OSTI ID:
406884
Research Organizations:
Universidad Nacional Autonoma de Mexico, Mexico City (Mexico). Facultad de Ciencias
Country of Origin:
Mexico
Language:
Spanish
Other Identifying Numbers:
Other: ON: DE97606183; TRN: MX9500075000826
Availability:
INIS; OSTI as DE97606183
Submitting Site:
INIS
Size:
72 p.
Announcement Date:

Citation Formats

Pimentel P, A E. Biological radiation effects of Radon in Drosophila; Efectos biologicos del radon en Drosophila. Mexico: N. p., 1995. Web.
Pimentel P, A E. Biological radiation effects of Radon in Drosophila; Efectos biologicos del radon en Drosophila. Mexico.
Pimentel P, A E. 1995. "Biological radiation effects of Radon in Drosophila; Efectos biologicos del radon en Drosophila." Mexico.
@misc{etde_406884,
title = {Biological radiation effects of Radon in Drosophila; Efectos biologicos del radon en Drosophila}
author = {Pimentel P, A E}
abstractNote = {In order to contribute to the knowledge on the effects of radon and its decay products, the aim of this investigation is to study the biological effects of radon using Drosophila melanogaster throught the somatic mutation and recombination test (SMART) and the analysis of some adaptative factors exposing larvaes to controlled radon atmosphers, considering that this insect could be used as biological monitor. Using the somatic mutation test a mutagenic effect was observed proportional to radon concentration, into an interval of 1 {+-} 0.3 to 111 {+-} 7.4 KBq/m{sup 3} equivalent to doses under 0.0106 Gy. The correlation analysis gives a linear (r=0.80) relationship with a positive slope of 0.2217. The same happens when gamma rays are used in the interval of 1 to 20 Gy, given a linear dose-dependent effect (r=0.878) is obtained; nevetheless the slop is smaller (m=0.003) than for radon. Analysing the results of adaptative factors of the nine exposed generations, it was found that probably radon exposition induced dominant lethals during gametogenesis or/and a selection of the more component gamets of the treated individuals in larval state. It was reflected in the significant decrease on fecundity of the generation exposed. Nevertheless the laying eggs had an increase in egg-to-adult viability and the develop velocity was higher than in control for 3 KBq/m{sup 3}, this suggest that radon concentrations used were able to induce repair mechanisms. These data agree with the Hormesis hypothesis that says: low doses have positive effects on health. It was not possible to obtain a dose-effect relationship except with the develop velocity where it was found a dose-effect inverse proportion. In conclusion, Drosophila melanogaster could be a good system to obtain in vivo damaged induction concentration dependent of radon and its decay products, as well as to study the effects in an exposed population by the analysis of adaptative factors. (Author).}
place = {Mexico}
year = {1995}
month = {Dec}
}