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Application of the Monte Carlo integration method in calculations of dose distributions in HDR-Brachytherapy

Abstract

Source anisotropy is a very important factor in brachytherapy quality assurance of high dose rate HDR Ir 192 afterloading stepping sources. If anisotropy is not taken into account then doses received by a brachytherapy patient in certain directions can be in error by a clinically significant amount. Experimental measurements of anisotropy are very labour intensive. We have shown that within acceptable limits of accuracy, Monte Carlo integration (MCI) of a modified Sievert integral (3D generalisation) can provide the necessary data within a much shorter time scale than can experiments. Hence MCI can be used for routine quality assurance schedules whenever a new design of HDR or PDR Ir 192 is used for brachytherapy afterloading. Our MCI calculation results are comparable with published experimental data and Monte Carlo simulation data for microSelectron and VariSource Ir 192 sources. We have shown not only that MCI offers advantages over alternative numerical integration methods, but also that treating filtration coefficients as radial distance-dependent functions improves Sievert integral accuracy at low energies. This paper also provides anisotropy data for three new Ir 192 sources, one for microSelectron-HDR and two for the microSelectron-PDR, for which data currently is not available. The information we have obtained in  More>>
Authors:
Baltas, D; Geramani, K N; Ioannidis, G T; Kolotas, C; Zamboglou, N; [1]  Giannouli, S [2] 
  1. Strahlenklinik, Stadtische Kliniken Offenbach, Offenbach (Germany)
  2. Department of Electrical and Computer Engineering, National Technical University of Athens, Athens (Greece)
Publication Date:
Dec 31, 1998
Product Type:
Conference
Report Number:
INIS-CY-0004; CONF-9806202-
Reference Number:
SCA: 550604; PA: AIX-30:017096; EDB-99:043449; SN: 99002082139
Resource Relation:
Conference: 8. Mediterranean conference on medical and biological engineering and computing (Medicon `98), Lemesos (Cyprus), 14-17 Jun 1998; Other Information: DN: The proceedings of this meeting are available on CD-ROM in PDF, at the price of US$50, from the Cyprus Association of Medical Physics and Biomedical Engineering, P.O.Box 24039, 1700 Nicosia, Cyprus. The CD-ROM makes use of Abode Acrobat PDF (Portable Document Format). To read the files the Abode Acrobat reader has to be installed on your system. A copy is provided with the CD-ROM; PBD: 1998; Related Information: Is Part Of Proceedings of the 8. Mediterranean Conference on Medical and Biological Engineering and Computing (Medicon `98); Christofides, Stelios; Pattichis, Constantinos; Schizas, Christos; Keravnou-Papailiou, Elpida; Kaplanis, Prodromos; Spyros, Spyrou; Christodoulides, George; Theodoulou, Yiannis [eds.]; PB: 220 p.
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; ANISOTROPY; IRIDIUM 192; MONTE CARLO METHOD; QUALITY ASSURANCE; RADIATION SOURCE IMPLANTS
OSTI ID:
331903
Research Organizations:
Cyprus Association of Medical Physics and Biomedical Engineering (CAMPBE), Nicosia (Cyprus); The Department of Computer Science, University of Cyprus, Nicosia (Cyprus)
Country of Origin:
Cyprus
Language:
English
Other Identifying Numbers:
Other: ON: DE99619912; ISBN 9963-607-14-4; TRN: CY9900019017096
Availability:
INIS; OSTI as DE99619912
Submitting Site:
INIS
Size:
pp. 131
Announcement Date:

Citation Formats

Baltas, D, Geramani, K N, Ioannidis, G T, Kolotas, C, Zamboglou, N, and Giannouli, S. Application of the Monte Carlo integration method in calculations of dose distributions in HDR-Brachytherapy. Cyprus: N. p., 1998. Web.
Baltas, D, Geramani, K N, Ioannidis, G T, Kolotas, C, Zamboglou, N, & Giannouli, S. Application of the Monte Carlo integration method in calculations of dose distributions in HDR-Brachytherapy. Cyprus.
Baltas, D, Geramani, K N, Ioannidis, G T, Kolotas, C, Zamboglou, N, and Giannouli, S. 1998. "Application of the Monte Carlo integration method in calculations of dose distributions in HDR-Brachytherapy." Cyprus.
@misc{etde_331903,
title = {Application of the Monte Carlo integration method in calculations of dose distributions in HDR-Brachytherapy}
author = {Baltas, D, Geramani, K N, Ioannidis, G T, Kolotas, C, Zamboglou, N, and Giannouli, S}
abstractNote = {Source anisotropy is a very important factor in brachytherapy quality assurance of high dose rate HDR Ir 192 afterloading stepping sources. If anisotropy is not taken into account then doses received by a brachytherapy patient in certain directions can be in error by a clinically significant amount. Experimental measurements of anisotropy are very labour intensive. We have shown that within acceptable limits of accuracy, Monte Carlo integration (MCI) of a modified Sievert integral (3D generalisation) can provide the necessary data within a much shorter time scale than can experiments. Hence MCI can be used for routine quality assurance schedules whenever a new design of HDR or PDR Ir 192 is used for brachytherapy afterloading. Our MCI calculation results are comparable with published experimental data and Monte Carlo simulation data for microSelectron and VariSource Ir 192 sources. We have shown not only that MCI offers advantages over alternative numerical integration methods, but also that treating filtration coefficients as radial distance-dependent functions improves Sievert integral accuracy at low energies. This paper also provides anisotropy data for three new Ir 192 sources, one for microSelectron-HDR and two for the microSelectron-PDR, for which data currently is not available. The information we have obtained in this study can be incorporated into clinical practice.}
place = {Cyprus}
year = {1998}
month = {Dec}
}