Abstract
Traditional methods used to evaluate protein metabolism left unanswered some of the relevant questions in public health in developing countries, such as growth retardation in children. Particularly, in developing countries, infection (clinical and subclinical) and malnutrition are still relevant problems, and the most important scientific issues for the application of stable isotope tracer methods are related to the impact of infection, such as the oxidative disposal of essential amino acids in well-nourished and malnourished children. The objectives of the present proposal are: (1) To simplify, make less expensive, less time-consuming, and less invasive, methods in clinical research on amino acid metabolism using stable-isotope tracers in children; and (2) To assess the effects of infection (clinical or subclinical) on whole-body protein turnover in children with and without malnutrition. The objectives involve the engineering and assessment of a portable instrument to be used in evaluations of protein oxidation in the developing world. Methodological issues such as intra- and inter-subject variability, which are of great importance for the interpretation of amino acid metabolism and protein turnover, will also be considered. 18 refs, 2 figs.
Mazariegos, M;
De Vettorazzi, C;
Solomons, N W;
[1]
Caballero, B
[2]
- Hospital de Ojos y Oidos ``Dr. Rodolfo Robles V.``, Guatemala City (Guatemala). Centre for Studies of Sensory Impairment, Aging and Metabolism (CeSSIAM)
- Johns Hopkins Univ., Baltimore, MD (United States). Centre for Human Nutrition
Citation Formats
Mazariegos, M, De Vettorazzi, C, Solomons, N W, and Caballero, B.
Essential amino acid metabolism in infected/non-infected, poor, Guatemalan children.
IAEA: N. p.,
1994.
Web.
Mazariegos, M, De Vettorazzi, C, Solomons, N W, & Caballero, B.
Essential amino acid metabolism in infected/non-infected, poor, Guatemalan children.
IAEA.
Mazariegos, M, De Vettorazzi, C, Solomons, N W, and Caballero, B.
1994.
"Essential amino acid metabolism in infected/non-infected, poor, Guatemalan children."
IAEA.
@misc{etde_29202,
title = {Essential amino acid metabolism in infected/non-infected, poor, Guatemalan children}
author = {Mazariegos, M, De Vettorazzi, C, Solomons, N W, and Caballero, B}
abstractNote = {Traditional methods used to evaluate protein metabolism left unanswered some of the relevant questions in public health in developing countries, such as growth retardation in children. Particularly, in developing countries, infection (clinical and subclinical) and malnutrition are still relevant problems, and the most important scientific issues for the application of stable isotope tracer methods are related to the impact of infection, such as the oxidative disposal of essential amino acids in well-nourished and malnourished children. The objectives of the present proposal are: (1) To simplify, make less expensive, less time-consuming, and less invasive, methods in clinical research on amino acid metabolism using stable-isotope tracers in children; and (2) To assess the effects of infection (clinical or subclinical) on whole-body protein turnover in children with and without malnutrition. The objectives involve the engineering and assessment of a portable instrument to be used in evaluations of protein oxidation in the developing world. Methodological issues such as intra- and inter-subject variability, which are of great importance for the interpretation of amino acid metabolism and protein turnover, will also be considered. 18 refs, 2 figs.}
place = {IAEA}
year = {1994}
month = {Dec}
}
title = {Essential amino acid metabolism in infected/non-infected, poor, Guatemalan children}
author = {Mazariegos, M, De Vettorazzi, C, Solomons, N W, and Caballero, B}
abstractNote = {Traditional methods used to evaluate protein metabolism left unanswered some of the relevant questions in public health in developing countries, such as growth retardation in children. Particularly, in developing countries, infection (clinical and subclinical) and malnutrition are still relevant problems, and the most important scientific issues for the application of stable isotope tracer methods are related to the impact of infection, such as the oxidative disposal of essential amino acids in well-nourished and malnourished children. The objectives of the present proposal are: (1) To simplify, make less expensive, less time-consuming, and less invasive, methods in clinical research on amino acid metabolism using stable-isotope tracers in children; and (2) To assess the effects of infection (clinical or subclinical) on whole-body protein turnover in children with and without malnutrition. The objectives involve the engineering and assessment of a portable instrument to be used in evaluations of protein oxidation in the developing world. Methodological issues such as intra- and inter-subject variability, which are of great importance for the interpretation of amino acid metabolism and protein turnover, will also be considered. 18 refs, 2 figs.}
place = {IAEA}
year = {1994}
month = {Dec}
}