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Significance of high-intensity signals on cranial MRI T{sub 2} weighted image in diagnosis of age-associated dementia. From a viewpoint of reversibility of brain function

Journal Article:

Abstract

This study was undertaken to determine whether changes of EEG band profile in patients showing high-intensity signal (HIS) on cranial magnetic resonance images (MRI), who had however no vascular lesions on cranial CT, were similar to those in multi-infarct dementia (MID) or senile dementia of Alzheimer type (SDAT) patients and to determine the significance of HIS in the diagnosis of SDAT. Forty-two patients with dementia diagnosed according to DSM-III-R were divided into HIS (n=21), MID (n=13), and SDAT (n=8) based on CT and MRI findings. Multi-infarcted lesions were seen on cranial CT and HIS was seen on cranial MRI in MID patients. There were no abnormal lesions except brain atrophy on cranial CT and MRI in SDAT patients. Appearance rates (%) of the 2-18 c/s frequency bands using computerized quantitative EEG before and after administration of protirelin tartrate (TRH-T) were analyzed in the frontal, central, parietal and occipital areas of the brain. There were no significant differences in appearance rates of EEG frequency bands before administration of TRH-T in HIS, MID, and SDAT patients. A significant decrease in appearance rates of slow waves and a significant increase in appearance rates of {alpha} waves were observed after administration of TRH-T in  More>>
Authors:
Kishiro, Masaki [1] 
  1. St. Marianna Univ., Kawasaki, Kanagawa (Japan). School of Medicine
Publication Date:
Aug 01, 1994
Product Type:
Journal Article
Reference Number:
SCA: 550602; PA: JPN-95:002314; EDB-95:059917; SN: 95001364983
Resource Relation:
Journal Name: Sei Marianna Ika Daigaku Zasshi; Journal Volume: 22; Journal Issue: 4; Other Information: PBD: Aug 1994
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; CEREBRUM; NMR IMAGING; SPIN-SPIN RELAXATION; MENTAL DISORDERS; BIOLOGICAL FUNCTIONS; ELDERLY PEOPLE; SIGNALS; TRH; VASCULAR DISEASES; ATROPHY; CAT SCANNING; ELECTROENCEPHALOGRAPHY
OSTI ID:
25719
Research Organizations:
No corporate text available (Country unknown/Code not available)
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: SMIZDS; ISSN 0387-2289; TRN: JP9502314
Submitting Site:
JPN
Size:
pp. 519-530
Announcement Date:

Journal Article:

Citation Formats

Kishiro, Masaki. Significance of high-intensity signals on cranial MRI T{sub 2} weighted image in diagnosis of age-associated dementia. From a viewpoint of reversibility of brain function. Japan: N. p., 1994. Web.
Kishiro, Masaki. Significance of high-intensity signals on cranial MRI T{sub 2} weighted image in diagnosis of age-associated dementia. From a viewpoint of reversibility of brain function. Japan.
Kishiro, Masaki. 1994. "Significance of high-intensity signals on cranial MRI T{sub 2} weighted image in diagnosis of age-associated dementia. From a viewpoint of reversibility of brain function." Japan.
@misc{etde_25719,
title = {Significance of high-intensity signals on cranial MRI T{sub 2} weighted image in diagnosis of age-associated dementia. From a viewpoint of reversibility of brain function}
author = {Kishiro, Masaki}
abstractNote = {This study was undertaken to determine whether changes of EEG band profile in patients showing high-intensity signal (HIS) on cranial magnetic resonance images (MRI), who had however no vascular lesions on cranial CT, were similar to those in multi-infarct dementia (MID) or senile dementia of Alzheimer type (SDAT) patients and to determine the significance of HIS in the diagnosis of SDAT. Forty-two patients with dementia diagnosed according to DSM-III-R were divided into HIS (n=21), MID (n=13), and SDAT (n=8) based on CT and MRI findings. Multi-infarcted lesions were seen on cranial CT and HIS was seen on cranial MRI in MID patients. There were no abnormal lesions except brain atrophy on cranial CT and MRI in SDAT patients. Appearance rates (%) of the 2-18 c/s frequency bands using computerized quantitative EEG before and after administration of protirelin tartrate (TRH-T) were analyzed in the frontal, central, parietal and occipital areas of the brain. There were no significant differences in appearance rates of EEG frequency bands before administration of TRH-T in HIS, MID, and SDAT patients. A significant decrease in appearance rates of slow waves and a significant increase in appearance rates of {alpha} waves were observed after administration of TRH-T in the four areas in MID patients compared with those before administration. No significant differences in appearance rates of EEG frequency bands were observed after administration of TRH-T in the four areas in HIS and SDAT patients compared with those before administration. Changes of the EEG band profile in HIS patients were similar to those in SDAT patients. In the presence of appearance of HSI on cranial MRI T{sub 2} weighted images, the possibility of SDAT patients cannot be excluded. Therefore, SDAT should be diagnosed based on both clinical data and the absence of brain vascular lesions on cranial CT. Also, HIS on MRI T{sub 2}-weighted images is considered to reflect non-vascular lesions. (J.N.P.).}
journal = {Sei Marianna Ika Daigaku Zasshi}
issue = {4}
volume = {22}
journal type = {AC}
place = {Japan}
year = {1994}
month = {Aug}
}