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The study of the digestive absorption of water in patients suffering from cirrhosis of the liver, by using two hydrogen tracers; etude de l'absorption digestive de l'eau chez les malades atteints de cirrhose du foie a l'aide de deux indicateurs de l'hydrogene

Technical Report:

Abstract

We have studied the rate of appearance of ingested water in the peripheral blood of four patients suffering from cirrhosis of the liver with ascites. For this purpose, oral administration of deuterium oxide and intravenous administration of tritiated water were made simultaneously. This double experiment enables the phenomenon of diffusion of the tracer outside the vascular regions to be observed and calculation to be made of the amounts absorbed by the digestive tract and transferred to the peripheral circulation. The rate of absorption observed under the above conditions proves to be distinctly less (1.2 percent per minute of the ingested dose) than that observed by Scholer and Code in normal subjects (9 percent per minute of the ingested dose). Hypotheses are advanced which could account for the facts observed and which offer a satisfactory explanation of Gilbert's opsiuria. Reprint of a paper published in International Journal of Applied Radiation and Isotopes, vol. 7, p. 233-243, 1960 [French] Nous avons etudie chez quatre malades atteints de cirrhose du foie avec ascite, la vitesse d'apparition dans le sang peripherique de l'eau ingeree. A cet effet, nous avons administre simultanement a nos malades de l'oxyde de deuterium par voie orale et de l'eau  More>>
Authors:
Laine-Boszormenyi, M.; [1]  Fallot, P.; Masson, J.; Calvet, P. [2] 
  1. Institut National d'Hygiene (France)
  2. Commissariat a l'energie atomique et aux energies alternatives - CEA, Service de, CEA Saclay (France)
Publication Date:
Jul 01, 1960
Product Type:
Technical Report
Report Number:
CEA-R-1497
Resource Relation:
Other Information: 28 refs.; Available from the INIS Liaison Officer for France, see the 'INIS contacts' section of the INIS website for current contact and E-mail addresses: http://www.iaea.org/inis/Contacts/
Subject:
60 APPLIED LIFE SCIENCES; ABUNDANCE; ASCITES; CORRECTIONS; DIFFUSION; DUAL-ISOTOPE SUBTRACTION TECHNIQUE; EDEMA; HEAVY WATER; INTESTINAL ABSORPTION; INTRAVENOUS INJECTION; ISOTOPE RATIO; LIVER CIRRHOSIS; MASS SPECTROSCOPY; PATIENTS; POPOP; RADIONUCLIDE KINETICS; TRITIUM OXIDES
OSTI ID:
22682677
Research Organizations:
Commissariat a l'energie atomique et aux energies alternatives - CEA, Centre d'Etudes Nucleaires de Saclay, Service de Documentation, BP No.2, 91190 Gif-sur-Yvette (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR1801460031329
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
13 page(s)
Announcement Date:
May 04, 2018

Technical Report:

Citation Formats

Laine-Boszormenyi, M., Fallot, P., Masson, J., and Calvet, P. The study of the digestive absorption of water in patients suffering from cirrhosis of the liver, by using two hydrogen tracers; etude de l'absorption digestive de l'eau chez les malades atteints de cirrhose du foie a l'aide de deux indicateurs de l'hydrogene. France: N. p., 1960. Web.
Laine-Boszormenyi, M., Fallot, P., Masson, J., & Calvet, P. The study of the digestive absorption of water in patients suffering from cirrhosis of the liver, by using two hydrogen tracers; etude de l'absorption digestive de l'eau chez les malades atteints de cirrhose du foie a l'aide de deux indicateurs de l'hydrogene. France.
Laine-Boszormenyi, M., Fallot, P., Masson, J., and Calvet, P. 1960. "The study of the digestive absorption of water in patients suffering from cirrhosis of the liver, by using two hydrogen tracers; etude de l'absorption digestive de l'eau chez les malades atteints de cirrhose du foie a l'aide de deux indicateurs de l'hydrogene." France.
@misc{etde_22682677,
title = {The study of the digestive absorption of water in patients suffering from cirrhosis of the liver, by using two hydrogen tracers; etude de l'absorption digestive de l'eau chez les malades atteints de cirrhose du foie a l'aide de deux indicateurs de l'hydrogene}
author = {Laine-Boszormenyi, M., Fallot, P., Masson, J., and Calvet, P.}
abstractNote = {We have studied the rate of appearance of ingested water in the peripheral blood of four patients suffering from cirrhosis of the liver with ascites. For this purpose, oral administration of deuterium oxide and intravenous administration of tritiated water were made simultaneously. This double experiment enables the phenomenon of diffusion of the tracer outside the vascular regions to be observed and calculation to be made of the amounts absorbed by the digestive tract and transferred to the peripheral circulation. The rate of absorption observed under the above conditions proves to be distinctly less (1.2 percent per minute of the ingested dose) than that observed by Scholer and Code in normal subjects (9 percent per minute of the ingested dose). Hypotheses are advanced which could account for the facts observed and which offer a satisfactory explanation of Gilbert's opsiuria. Reprint of a paper published in International Journal of Applied Radiation and Isotopes, vol. 7, p. 233-243, 1960 [French] Nous avons etudie chez quatre malades atteints de cirrhose du foie avec ascite, la vitesse d'apparition dans le sang peripherique de l'eau ingeree. A cet effet, nous avons administre simultanement a nos malades de l'oxyde de deuterium par voie orale et de l'eau tritiee par voie intraveineuse. Cette double epreuve permet de faire la part du phenomene de diffusion de 11 indicateur hors des territoires vasculaires et de calculer les quantites absorbees par le tube digestif et transferees dans la circulation peripherique. La vitesse d'absorption appreciee dans les conditions precedentes (1,2 pour cent par minute de la dose ingeree) s'avere notablement inferieure a celle observee par SCHOLER et CODE chez les sujets normaux (9 pour cent par minute de la dose ingeree). Nous avons evoque des hypotheses susceptibles de rendre compte des faits observes qui apportent une explication satisfaisante a l'opsiurie de Gilbert. Reproduction d'un article publie dans International Journal of Applied Radiation and Isotopes, vol. 7, p. 233-243, 1960.}
place = {France}
year = {1960}
month = {Jul}
}