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Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie

Thesis/Dissertation:

Abstract

This academic report concerns a study during which cerium 144 has been intravenously injected to three-month old rats under the form of cerium chloride in aqueous solution with pH of 9,5. Rats have then been sacrificed at different times after the injection, and organ or tissue samplings have been performed to study the isotope distribution in their bodies. This allowed the calculation of internal irradiation doses locally received by the animal, and also to identify critical organs with respect to cerium 144. Thus, until the twentieth day after injection, liver is the critical organ. After, it is the skeleton, for the rest of the animal's life. The bone internal irradiation is the highest danger for an internal cerium 144 contamination, due to threats on body hematopoietic functions [French] Le Cerium 144 est injecte a des rats de trois mois par voie intraveineuse, sous forme de chlorure en solution aqueuse a pH = 9,5. Une telle solution est colloidale. Les rats sont sacrifies par groupe de 5 a des temps differents apres l'injection et des prelevements d'organes ou de tissus sont effectues qui permettent d'etudier la distribution de l'isotope dans l'organisme. Cette etude de la distribution du Cerium 144 dans l'organiqme  More>>
Authors:
Publication Date:
Jul 01, 1959
Product Type:
Thesis/Dissertation
Report Number:
FRCEA-TH-8849
Resource Relation:
Other Information: 15 refs.; Available from the INIS Liaison Officer for France, see the 'INIS contacts' section of the INIS website for current contact and E-mail addresses: http://www.iaea.org/inis/Contacts/; Diplome de Radiobiologie de l'INSTN Saclay
Subject:
60 APPLIED LIFE SCIENCES; 63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; 61 RADIATION PROTECTION AND DOSIMETRY; ANIMAL TISSUES; BIOLOGICAL RADIATION EFFECTS; CERIUM 144; CERIUM CHLORIDES; CONTAMINATION; DOSIMETRY; EXCRETION; INTERNAL IRRADIATION; LIVER; METABOLISM; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIONUCLIDE KINETICS; RATS; SKELETAL DISEASES; SKELETON; TISSUE DISTRIBUTION
OSTI ID:
22632841
Research Organizations:
Faculte des Sciences de l'Universite de Paris (France); Commissariat a l'energie atomique et aux energies alternatives - CEA, Centre d'Etudes Nucleaires de Saclay, Service de Biologie (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR1702123081007
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
35 page(s)
Announcement Date:
Oct 24, 2017

Thesis/Dissertation:

Citation Formats

Remy, Jacques. Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie. France: N. p., 1959. Web.
Remy, Jacques. Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie. France.
Remy, Jacques. 1959. "Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie." France.
@misc{etde_22632841,
title = {Metabolism of cerium 144 in rat. Distribution - elimination - dosimetry; Metabolisme du cerium 144 chez le rat. Distribution - elimination - dosimetrie}
author = {Remy, Jacques}
abstractNote = {This academic report concerns a study during which cerium 144 has been intravenously injected to three-month old rats under the form of cerium chloride in aqueous solution with pH of 9,5. Rats have then been sacrificed at different times after the injection, and organ or tissue samplings have been performed to study the isotope distribution in their bodies. This allowed the calculation of internal irradiation doses locally received by the animal, and also to identify critical organs with respect to cerium 144. Thus, until the twentieth day after injection, liver is the critical organ. After, it is the skeleton, for the rest of the animal's life. The bone internal irradiation is the highest danger for an internal cerium 144 contamination, due to threats on body hematopoietic functions [French] Le Cerium 144 est injecte a des rats de trois mois par voie intraveineuse, sous forme de chlorure en solution aqueuse a pH = 9,5. Une telle solution est colloidale. Les rats sont sacrifies par groupe de 5 a des temps differents apres l'injection et des prelevements d'organes ou de tissus sont effectues qui permettent d'etudier la distribution de l'isotope dans l'organisme. Cette etude de la distribution du Cerium 144 dans l'organiqme du rat a permis egalement le calcul des doses d'irradiation interne recues localement par l'animal. Ces donnees permettent de definir les organes critiques de l'organisme pour le Cerium 144: Jusqu'au 20eme jour l'organe critique est le foie. Ce sera ensuite le squelette, et ce, pendant toute la vie de l'animal. L'irradiation interne de l'os constitue, en raison des menaces qu'elle comporte pour les fonctions hematopoietiques de l'organisme, le plus grand danger d'une contamination interne par le Cerium 144.}
place = {France}
year = {1959}
month = {Jul}
}