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The correlation of the lymphocyte infiltration in PTC with the clinic pathological character

Abstract

Objective: To explore the correlation of the lymphocyte infiltration in PTC with the clinicopathological character. Methods: 51 papillary thyroid cancer patients undergoing surgery and radioiodine therapy were reviewed in this study. The paraffin-embedded tissues of the patients were selected to confirm the lymphocyte infiltration degree I to III from the least to the mast, and DNA extraction and BRAF mutation analysis were done. The clinic pathological features including: sex, age, TgAb, neck lymph node metastasis, distant metastasis, free of disease. χ{sup 2} test was used to analyze the correlation between the lymphocyte infiltration and the clinic pathological features. Results: 51 PTC patients, 24 were observed of lymphocyte infiltration grade I, 12 grade 2 and 15 grade 3. TGAb level was 54.21 ± 96.48, 74.53 ± 153.03, 195.33 ± 182.49 from grade I to III, and that was statistically different among the three group. The BRAF gene status, remission, age, neck lymph node metastasis, distant metastasis were not found correlated with the lymphocyte infiltration state. Conclusions: Papillary thyroid cancer patients with large lymphocyte infiltration were ape to have higher thyroglobulin antibody level. (authors)
Authors:
Wenli, Dai; Bangping, Cui; Tao, Hu; Kai, Yan; Wei, Hu; [1]  Yichang Central People's Hospital, Yichang (China); Yichang Key Laboratory of Molecular Imaging of Nuclear Medicine, Yichang (China)]
  1. The First College of Clinical Medical Science, China Three Gorges University, Yichang (China)
Publication Date:
May 15, 2014
Product Type:
Conference
Resource Relation:
Conference: 2013 academic annual meeting of China Nuclear Society, Harbin (China), 10-14 Sep 2013; Other Information: 1 tab., 5 refs.; Related Information: In: Progress report on nuclear science and technology in China (Vol.3). Proceedings of academic annual meeting of China Nuclear Society in 2013, No.9--nuclear medicine sub-volume| 96 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ANIMAL TISSUES; ANTIBODIES; DNA; GENES; LYMPH NODES; LYMPHOCYTES; METASTASES; MUTATIONS; NECK; NEOPLASMS; PATIENTS; RADIOTHERAPY; REVIEWS; SURGERY; THYROGLOBULIN; THYROID
OSTI ID:
22621475
Research Organizations:
China Nuclear Physics Society (China)
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Other: ISBN 978-7-5022-6130-6; TRN: CN1701418068733
Submitting Site:
INIS
Size:
page(s) 46-49
Announcement Date:
Sep 20, 2017

Citation Formats

Wenli, Dai, Bangping, Cui, Tao, Hu, Kai, Yan, Wei, Hu, Yichang Central People's Hospital, Yichang (China), and Yichang Key Laboratory of Molecular Imaging of Nuclear Medicine, Yichang (China)]. The correlation of the lymphocyte infiltration in PTC with the clinic pathological character. China: N. p., 2014. Web.
Wenli, Dai, Bangping, Cui, Tao, Hu, Kai, Yan, Wei, Hu, Yichang Central People's Hospital, Yichang (China), & Yichang Key Laboratory of Molecular Imaging of Nuclear Medicine, Yichang (China)]. The correlation of the lymphocyte infiltration in PTC with the clinic pathological character. China.
Wenli, Dai, Bangping, Cui, Tao, Hu, Kai, Yan, Wei, Hu, Yichang Central People's Hospital, Yichang (China), and Yichang Key Laboratory of Molecular Imaging of Nuclear Medicine, Yichang (China)]. 2014. "The correlation of the lymphocyte infiltration in PTC with the clinic pathological character." China.
@misc{etde_22621475,
title = {The correlation of the lymphocyte infiltration in PTC with the clinic pathological character}
author = {Wenli, Dai, Bangping, Cui, Tao, Hu, Kai, Yan, Wei, Hu, Yichang Central People's Hospital, Yichang (China), and Yichang Key Laboratory of Molecular Imaging of Nuclear Medicine, Yichang (China)]}
abstractNote = {Objective: To explore the correlation of the lymphocyte infiltration in PTC with the clinicopathological character. Methods: 51 papillary thyroid cancer patients undergoing surgery and radioiodine therapy were reviewed in this study. The paraffin-embedded tissues of the patients were selected to confirm the lymphocyte infiltration degree I to III from the least to the mast, and DNA extraction and BRAF mutation analysis were done. The clinic pathological features including: sex, age, TgAb, neck lymph node metastasis, distant metastasis, free of disease. χ{sup 2} test was used to analyze the correlation between the lymphocyte infiltration and the clinic pathological features. Results: 51 PTC patients, 24 were observed of lymphocyte infiltration grade I, 12 grade 2 and 15 grade 3. TGAb level was 54.21 ± 96.48, 74.53 ± 153.03, 195.33 ± 182.49 from grade I to III, and that was statistically different among the three group. The BRAF gene status, remission, age, neck lymph node metastasis, distant metastasis were not found correlated with the lymphocyte infiltration state. Conclusions: Papillary thyroid cancer patients with large lymphocyte infiltration were ape to have higher thyroglobulin antibody level. (authors)}
place = {China}
year = {2014}
month = {May}
}