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Synthesis and anticancer evaluation of (-1)- aretigenin derivatives

Abstract

Seven (-)-arctigenin derivatives 1-7 were designed and synthesized by using Mannich and acylation methods to improve the activity and bioavailability of (-)-arctigenin. Structures of compounds 1-7 were elucidated on the basis of spectroscopic analysis and chemical evidence. Anticancer activity of these compounds on SGC7901 was assayed in vitro. (author)
Authors:
Xu, Y.; Chen, G. [1] 
  1. Liaoning Univ. of Traditional Chinese Medicine, Dalian (China)
Publication Date:
Oct 15, 2014
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of the Chemical Society of Pakistan; Journal Volume: 36; Journal Issue: 5
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 60 APPLIED LIFE SCIENCES; ACETIC ACID; BIOLOGICAL ACCUMULATION; CHROMATOGRAPHY; ETHANOL; FRUITS; SILICA GEL; SYNTHESIS; TUMOR CELLS
OSTI ID:
22426985
Country of Origin:
Pakistan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0253-5106; TRN: PK1501104132961
Submitting Site:
INIS
Size:
page(s) 870-874
Announcement Date:
Feb 08, 2016

Citation Formats

Xu, Y., and Chen, G. Synthesis and anticancer evaluation of (-1)- aretigenin derivatives. Pakistan: N. p., 2014. Web.
Xu, Y., & Chen, G. Synthesis and anticancer evaluation of (-1)- aretigenin derivatives. Pakistan.
Xu, Y., and Chen, G. 2014. "Synthesis and anticancer evaluation of (-1)- aretigenin derivatives." Pakistan.
@misc{etde_22426985,
title = {Synthesis and anticancer evaluation of (-1)- aretigenin derivatives}
author = {Xu, Y., and Chen, G.}
abstractNote = {Seven (-)-arctigenin derivatives 1-7 were designed and synthesized by using Mannich and acylation methods to improve the activity and bioavailability of (-)-arctigenin. Structures of compounds 1-7 were elucidated on the basis of spectroscopic analysis and chemical evidence. Anticancer activity of these compounds on SGC7901 was assayed in vitro. (author)}
journal = []
issue = {5}
volume = {36}
journal type = {AC}
place = {Pakistan}
year = {2014}
month = {Oct}
}