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The Use of Tygon Tubing Sterilized by Gamma Radiation in Heart-Lung By-Pass Machines

Conference:

Abstract

Tygon tubing is a co-polymer polyvinyl chloride. This tubing is used throughout the circuit of our heart-lung by-pass machines and had been sterilized by autoclaving or exposure to ethylene oxide gas. Tubing sterilized by autoclaving was noted to have a decrease in tensile strength and the transparency of the tubing was affected. Sterilization by ethylene oxide had the disadvantage that gas was often present in the lumen of the tube when connected to the machine. Lengths of Tygon tubing were sterilized by gamma radiation at varying radiation levels and temperatures. Bacteriological studies were done on the tubing and estimation of tensile strength carried out. We have found that a level of radiation of 2. 5 to 3. 0 Mrad at 20°C produces little or no change in tensile strength and the tubing remains bacteriologically sterile. Tygon tubing sterilized in this way has now been used in over sixty heart-lung by-pass machine operations. (author)
Authors:
Alladine, M. F.; Gibbons, J. R. P. [1] 
  1. London Chest Hospital, London (United Kingdom)
Publication Date:
Sep 15, 1967
Product Type:
Conference
Report Number:
IAEA-SM-92/23
Resource Relation:
Conference: Symposium on Radiosterilization of Medical Products, Budapest (Hungary), 5-9 Jun 1967, Panel Meeting on a Code of Practice for the Radiosterilization of Medical Products, Vienna (Austria), 5-9 Dec 1966; Other Information: 1 ref., 1 fig., 1 tab.; Related Information: In: Radiosterilization of Medical Products and Recommended Code of Practice. Proceedings of a Symposium| 481 p.
Subject:
60 APPLIED LIFE SCIENCES; AUTOCLAVES; COPOLYMERS; ETHYLENE; GAMMA RADIATION; HEART; LUNGS; OPACITY; OXIDES; PVC; STERILIZATION; TENSILE PROPERTIES; TUBES
OSTI ID:
22423983
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA15M0449129910
Submitting Site:
INIS
Size:
page(s) 285-288
Announcement Date:
Jan 09, 2016

Conference:

Citation Formats

Alladine, M. F., and Gibbons, J. R. P. The Use of Tygon Tubing Sterilized by Gamma Radiation in Heart-Lung By-Pass Machines. IAEA: N. p., 1967. Web.
Alladine, M. F., & Gibbons, J. R. P. The Use of Tygon Tubing Sterilized by Gamma Radiation in Heart-Lung By-Pass Machines. IAEA.
Alladine, M. F., and Gibbons, J. R. P. 1967. "The Use of Tygon Tubing Sterilized by Gamma Radiation in Heart-Lung By-Pass Machines." IAEA.
@misc{etde_22423983,
title = {The Use of Tygon Tubing Sterilized by Gamma Radiation in Heart-Lung By-Pass Machines}
author = {Alladine, M. F., and Gibbons, J. R. P.}
abstractNote = {Tygon tubing is a co-polymer polyvinyl chloride. This tubing is used throughout the circuit of our heart-lung by-pass machines and had been sterilized by autoclaving or exposure to ethylene oxide gas. Tubing sterilized by autoclaving was noted to have a decrease in tensile strength and the transparency of the tubing was affected. Sterilization by ethylene oxide had the disadvantage that gas was often present in the lumen of the tube when connected to the machine. Lengths of Tygon tubing were sterilized by gamma radiation at varying radiation levels and temperatures. Bacteriological studies were done on the tubing and estimation of tensile strength carried out. We have found that a level of radiation of 2. 5 to 3. 0 Mrad at 20°C produces little or no change in tensile strength and the tubing remains bacteriologically sterile. Tygon tubing sterilized in this way has now been used in over sixty heart-lung by-pass machine operations. (author)}
place = {IAEA}
year = {1967}
month = {Sep}
}