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ETDEWEB   /       /    Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production

Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production

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Abstract

Oxygen-18 enriched water has been recovered from IBA (Ion Beam Applications) recovery system followed by purification and then used in the production of {sup 18}F-. The purification process has been carried out by irradiation with UV followed by a distillation under vacuum. After purification, 95% of water is recovered and organic compounds, radioisotopes, trace metals and gases are eliminated efficiently. Results show that there are no significant differences in (2-deoxy-2-[{sup 18}F]fluoro-D-glucose ([{sup 18}F]FDG) production yield using purified water by the proposed method and new enriched water. Tritium was detected in the irradiated enriched water. Contamination precautions during purification should be considered. Tritium was not present in {sup 18}FDG or Na-{sup 18}F final products. (author)
Authors:
Al Rayyes, A. H. [1] 
  1. Atomic Energy Commission of Syria, Chemistry Department, Cyclotron Division, Damascus (Syrian Arab Republic)
Publication Date:
Jul 01, 2009
Product Type:
Conference
Report Number:
IAEA-RC-1025.3
Resource Relation:
Conference: 3. Research Coordination Meeting on Improved High Current Liquid and Gas Targets for Cyclotron Produced Radioisotopes, Vienna (Austria), 5-9 Oct 2009; Other Information: 8 refs., 5 figs., 2 tabs.; Related Information: In: Report of the 3{sup rd} RCM on Improved High Current Liquid and Gas Targets for Cyclotron Produced Radioisotopes| 141 p.
Subject:
07 ISOTOPES AND RADIATION SOURCES; BEAMS; CONTAMINATION; DISTILLATION; FLUORINE 18; GLUCOSE; HYDROGEN; IRRADIATION; OXYGEN 18; PURIFICATION; TRITIUM; WATER
OSTI ID:
22342470
Research Organizations:
International Atomic Energy Agency, Industrial Applications and Chemistry Section, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
TRN: XA14M3095048804
Availability:
Available from INIS in electronic form. Also available on-line: http://www-naweb.iaea.org/napc/iachem/meetings/RCMs/RC-1025-3_report_complete.pdf
Submitting Site:
INIS
Size:
page(s) 82-89
Announcement Date:
Jun 19, 2015

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Citation Formats

Al Rayyes, A. H. Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production. IAEA: N. p., 2009. Web.
Al Rayyes, A. H. Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production. IAEA.
Al Rayyes, A. H. 2009. "Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production." IAEA.
@misc{etde_22342470,
title = {Enriched Water-H{sub 2} {sup 18}O Purification to be Used in Routine {sup 18}FDG Production}
 author = {Al Rayyes, A. H.}
 abstractNote = {Oxygen-18 enriched water has been recovered from IBA (Ion Beam Applications) recovery system followed by purification and then used in the production of {sup 18}F-. The purification process has been carried out by irradiation with UV followed by a distillation under vacuum. After purification, 95% of water is recovered and organic compounds, radioisotopes, trace metals and gases are eliminated efficiently. Results show that there are no significant differences in (2-deoxy-2-[{sup 18}F]fluoro-D-glucose ([{sup 18}F]FDG) production yield using purified water by the proposed method and new enriched water. Tritium was detected in the irradiated enriched water. Contamination precautions during purification should be considered. Tritium was not present in {sup 18}FDG or Na-{sup 18}F final products. (author)}
 place = {IAEA}
 year = {2009}
 month = {Jul}
 }