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Correlation between coronary artery calcification and the need for revascularization in patients with no previous diagnosis of arterial coronary disease

Abstract

Introduction: about half of deaths from coronary heart disease (CHD) are not preceded by cardiac symptoms or previous diagnosis. Quantification of coronary artery calcification (CAC) by computed tomography is a strong predictor of events and improves the stratification the Framingham Risk Score. Objective: to evaluate the ability of the calcium score to predict the necessity invasive treatment (bypass (CABG) or intervention coronary percutaneous (ICP)) with no previous CAD. Method: retrospective study in pts without prior CAD and with quantification of CAC during 2009. The CAC was obtained in 64 multislice CT without contrast, with synchronized ECG acquisition, 120kV, 80-100mA, radiation <1mSv, and measured by the Agatston calcium score (CS) (threshold of 130 HU). Mean, median, and diagnostic tests were used. Results: We evaluated 263 pts (171 men), 59±13 years, BMI = 27.7 kg/m2, and mean follow up of 18±3 months. The total CS was 199.5±24.39. In patients with diabetes (DM), the CS was 320.5±67.56 and 166±24.47 in non-DM. The 23 patients who underwent invasive treatment had an average CS of 692 ± 72.3 versus 134.7 ± 21.35 in patients not treated (p <0.001). Of the 47 pts with CS ≥ 400, 17 were treated (CABG or ICP). Of the 216  More>>
Authors:
Prazeres, Carlos Eduardo Elias dos; Cury, Roberto Caldeira; Bello, Juliana Hiromi Silva Matsumoto; [1]  Magalhaes, Tiago Augusto; [2]  Moreira, Valeria de Melo; Carlos Eduardo Rochitte, E-mail: rochitte@gmail.com, E-mail: crochitte@hcor.com.br [3] 
  1. Instituto do Coracao (InCor/FM/USP), Sao paulo, SP (Brazil)
  2. Hospital Pro-Cardiaco, Rio de Janeiro, RJ (Brazil)
  3. Hospital do Coracao (HCOR), Sao Paulo, SP (Brazil)
Publication Date:
Oct 15, 2012
Product Type:
Journal Article
Resource Relation:
Journal Name: Revista Brasileira de Ecocardiografia e Imagem Cardiovascular; Journal Volume: 25; Journal Issue: 4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CALCIUM; CARDIOVASCULAR DISEASES; COMPUTERIZED TOMOGRAPHY; CORONARIES; DIAGNOSIS; MYOCARDIUM; PATIENTS
OSTI ID:
22340767
Country of Origin:
Brazil
Language:
English; Portuguese; Spanish
Other Identifying Numbers:
Journal ID: ISSN 1984-3038; TRN: BR1500464047088
Availability:
Available from http://departamentos.cardiol.br/sbc-depeco/publicacoes/revista/2012/ingles/Revista04/07-correlation.pdf
Submitting Site:
BRN
Size:
page(s) 278-284
Announcement Date:
Jun 18, 2015

Citation Formats

Prazeres, Carlos Eduardo Elias dos, Cury, Roberto Caldeira, Bello, Juliana Hiromi Silva Matsumoto, Magalhaes, Tiago Augusto, Moreira, Valeria de Melo, and Carlos Eduardo Rochitte, E-mail: rochitte@gmail.com, E-mail: crochitte@hcor.com.br. Correlation between coronary artery calcification and the need for revascularization in patients with no previous diagnosis of arterial coronary disease. Brazil: N. p., 2012. Web.
Prazeres, Carlos Eduardo Elias dos, Cury, Roberto Caldeira, Bello, Juliana Hiromi Silva Matsumoto, Magalhaes, Tiago Augusto, Moreira, Valeria de Melo, & Carlos Eduardo Rochitte, E-mail: rochitte@gmail.com, E-mail: crochitte@hcor.com.br. Correlation between coronary artery calcification and the need for revascularization in patients with no previous diagnosis of arterial coronary disease. Brazil.
Prazeres, Carlos Eduardo Elias dos, Cury, Roberto Caldeira, Bello, Juliana Hiromi Silva Matsumoto, Magalhaes, Tiago Augusto, Moreira, Valeria de Melo, and Carlos Eduardo Rochitte, E-mail: rochitte@gmail.com, E-mail: crochitte@hcor.com.br. 2012. "Correlation between coronary artery calcification and the need for revascularization in patients with no previous diagnosis of arterial coronary disease." Brazil.
@misc{etde_22340767,
title = {Correlation between coronary artery calcification and the need for revascularization in patients with no previous diagnosis of arterial coronary disease}
author = {Prazeres, Carlos Eduardo Elias dos, Cury, Roberto Caldeira, Bello, Juliana Hiromi Silva Matsumoto, Magalhaes, Tiago Augusto, Moreira, Valeria de Melo, and Carlos Eduardo Rochitte, E-mail: rochitte@gmail.com, E-mail: crochitte@hcor.com.br}
abstractNote = {Introduction: about half of deaths from coronary heart disease (CHD) are not preceded by cardiac symptoms or previous diagnosis. Quantification of coronary artery calcification (CAC) by computed tomography is a strong predictor of events and improves the stratification the Framingham Risk Score. Objective: to evaluate the ability of the calcium score to predict the necessity invasive treatment (bypass (CABG) or intervention coronary percutaneous (ICP)) with no previous CAD. Method: retrospective study in pts without prior CAD and with quantification of CAC during 2009. The CAC was obtained in 64 multislice CT without contrast, with synchronized ECG acquisition, 120kV, 80-100mA, radiation <1mSv, and measured by the Agatston calcium score (CS) (threshold of 130 HU). Mean, median, and diagnostic tests were used. Results: We evaluated 263 pts (171 men), 59±13 years, BMI = 27.7 kg/m2, and mean follow up of 18±3 months. The total CS was 199.5±24.39. In patients with diabetes (DM), the CS was 320.5±67.56 and 166±24.47 in non-DM. The 23 patients who underwent invasive treatment had an average CS of 692 ± 72.3 versus 134.7 ± 21.35 in patients not treated (p <0.001). Of the 47 pts with CS ≥ 400, 17 were treated (CABG or ICP). Of the 216 pts with CS <400, 6 underwent treatment. Of the treated pts, 15 without diabetes had average CS 672.7 ± 92.04 versus 728.3 ± 11 of DM (8pts). In pts without DM who not underwent invasive treatment (191 pts), only 18 pts had SC ≥ 400. Conclusion: CS ≥ 400 was a strong predictor of revascularization (CABG or ICP) with good diagnostic performance in patients without prior diagnosis of CAD in the following 18 months. (author)}
journal = {Revista Brasileira de Ecocardiografia e Imagem Cardiovascular}
issue = {4}
volume = {25}
journal type = {AC}
place = {Brazil}
year = {2012}
month = {Oct}
}