Abstract
Many areas of modern medicine are almost unimaginable without the use of different kinds of implants. They used as replacements, supports, auxiliary devices etc. for various parts or functions of the body. Their use has many advantages, however there could be some drawbacks too, like the possibility of rejection, inflammation and other side-effects. Many of these drawbacks are directly related to the materials used for the implant fabrication. Coatings are widely used to eliminate the unwanted effects appearing after the implantation. In addition to the protection and separation of tissues from the implant material they could also enhance the functionality and the acceptance of the artificial device and also promote the regeneration of the tissues after the intervention. Drug-eluting coatings are a good example for the latter. By delivery and controlled elution of drugs they could actively suppress inflammatory reactions, allergy and rejection of the implant, and their activity is localized to the place where these effects could mainly occur – to the region of the implant. This project is aimed to develop a drug-eluting porous polymer coating by radiation induced polymerization that can be used in different medical implants. The primary objects for this research are coronary stents however
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Veres, M.;
Beiler, B.;
Himics, L.;
Tóth, S.;
Koós, M., E-mail: vm@szfki.hu
[1]
- Hungarian Academy of Sciences, Research Institute for Solid State Physics and Optics, Department of Laser Applications, Konkoly Thege Miklós ut 29-33, 1121 Budapest, P.O. Box 49, 1525 Budapest (Hungary)
Citation Formats
Veres, M., Beiler, B., Himics, L., Tóth, S., and Koós, M., E-mail: vm@szfki.hu.
Porous Polymer Drug-Eluting Coating Prepared by Radiation Induced Polymerization.
IAEA: N. p.,
2010.
Web.
Veres, M., Beiler, B., Himics, L., Tóth, S., & Koós, M., E-mail: vm@szfki.hu.
Porous Polymer Drug-Eluting Coating Prepared by Radiation Induced Polymerization.
IAEA.
Veres, M., Beiler, B., Himics, L., Tóth, S., and Koós, M., E-mail: vm@szfki.hu.
2010.
"Porous Polymer Drug-Eluting Coating Prepared by Radiation Induced Polymerization."
IAEA.
@misc{etde_22309182,
title = {Porous Polymer Drug-Eluting Coating Prepared by Radiation Induced Polymerization}
author = {Veres, M., Beiler, B., Himics, L., Tóth, S., and Koós, M., E-mail: vm@szfki.hu}
abstractNote = {Many areas of modern medicine are almost unimaginable without the use of different kinds of implants. They used as replacements, supports, auxiliary devices etc. for various parts or functions of the body. Their use has many advantages, however there could be some drawbacks too, like the possibility of rejection, inflammation and other side-effects. Many of these drawbacks are directly related to the materials used for the implant fabrication. Coatings are widely used to eliminate the unwanted effects appearing after the implantation. In addition to the protection and separation of tissues from the implant material they could also enhance the functionality and the acceptance of the artificial device and also promote the regeneration of the tissues after the intervention. Drug-eluting coatings are a good example for the latter. By delivery and controlled elution of drugs they could actively suppress inflammatory reactions, allergy and rejection of the implant, and their activity is localized to the place where these effects could mainly occur – to the region of the implant. This project is aimed to develop a drug-eluting porous polymer coating by radiation induced polymerization that can be used in different medical implants. The primary objects for this research are coronary stents however these porous layers could have perspective in other types of medical devices too. The main objectives are to develop a method for coating the surface of medical grade metallic alloy wires, plates and tubes with a porous polymer nanocomposite layer prepared by radiation induced polymerization and to characterize the obtained coatings.}
place = {IAEA}
year = {2010}
month = {Jul}
}
title = {Porous Polymer Drug-Eluting Coating Prepared by Radiation Induced Polymerization}
author = {Veres, M., Beiler, B., Himics, L., Tóth, S., and Koós, M., E-mail: vm@szfki.hu}
abstractNote = {Many areas of modern medicine are almost unimaginable without the use of different kinds of implants. They used as replacements, supports, auxiliary devices etc. for various parts or functions of the body. Their use has many advantages, however there could be some drawbacks too, like the possibility of rejection, inflammation and other side-effects. Many of these drawbacks are directly related to the materials used for the implant fabrication. Coatings are widely used to eliminate the unwanted effects appearing after the implantation. In addition to the protection and separation of tissues from the implant material they could also enhance the functionality and the acceptance of the artificial device and also promote the regeneration of the tissues after the intervention. Drug-eluting coatings are a good example for the latter. By delivery and controlled elution of drugs they could actively suppress inflammatory reactions, allergy and rejection of the implant, and their activity is localized to the place where these effects could mainly occur – to the region of the implant. This project is aimed to develop a drug-eluting porous polymer coating by radiation induced polymerization that can be used in different medical implants. The primary objects for this research are coronary stents however these porous layers could have perspective in other types of medical devices too. The main objectives are to develop a method for coating the surface of medical grade metallic alloy wires, plates and tubes with a porous polymer nanocomposite layer prepared by radiation induced polymerization and to characterize the obtained coatings.}
place = {IAEA}
year = {2010}
month = {Jul}
}