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Management of radiation injuries by natural herbs and neutraceuticals

Abstract

In the era of expanding nuclear energy program all over world, the role of radiation biology has acquired greater relevance and significance in addressing the health and environment issues. In view of constant human exposure to background radiation both naturally and man made e.g nuclear power plants and weapons testing, consumer products, medical X-ray, uranium mining and milling etc., the radiobiological research has been devoted to induction of cancer and evaluation of genetic effects. In the present time, nuclear terrorism and weapon related effects are raising much alarm and concern to public health. Obviously, radiation biology research has great potential in diagnosis, therapy and establishing standards for assessment risk from radiation exposure. The development of effective medical countermeasures to protect, mitigate, and treat normal tissue injury needs urgent investigation for basic molecular mechanisms and developing appropriate ready to-use kits using relevant cellular, animal model and clinical trails for practical purposes. Since the use of synthetic compounds is associated with the inherent toxicity, attention in recent years has been directed towards developing radiation countermeasure agents from the natural sources and/or nature-identical molecules. The rich biodiversity available in the Indian subcontinent has yielded several new drugs that find application in the modern  More>>
Authors:
Goyal, P.K., E-mail: pkgoyal2002@gmail.com [1] 
  1. Radiation and Cancer Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur (India)
Publication Date:
Oct 15, 2013
Product Type:
Conference
Resource Relation:
Conference: ICRB-2013: international conference on radiation biology and clinical applications, Mangalore (India), 25-27 Oct 2013; Related Information: In: Proceedings of the international conference on radiation biology and clinical applications: a molecular approach towards innovations in applied radiobiology and a workshop on strategies in radiation research| 90 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; GENETIC RADIATION EFFECTS; HEALTH HAZARDS; HERBS; MEDICINAL PLANTS; NEOPLASMS; NUCLEAR MEDICINE; RADIATION DOSES; RISK ASSESSMENT
OSTI ID:
22286822
Research Organizations:
Indian Society for Radiation Biology, Delhi (India); K.S. Hegde Medical Academy, Mangalore (India)
Country of Origin:
India
Language:
English
Other Identifying Numbers:
TRN: IN1402898108255
Submitting Site:
INIS
Size:
page(s) 17
Announcement Date:
Dec 19, 2014

Citation Formats

Goyal, P.K., E-mail: pkgoyal2002@gmail.com. Management of radiation injuries by natural herbs and neutraceuticals. India: N. p., 2013. Web.
Goyal, P.K., E-mail: pkgoyal2002@gmail.com. Management of radiation injuries by natural herbs and neutraceuticals. India.
Goyal, P.K., E-mail: pkgoyal2002@gmail.com. 2013. "Management of radiation injuries by natural herbs and neutraceuticals." India.
@misc{etde_22286822,
title = {Management of radiation injuries by natural herbs and neutraceuticals}
author = {Goyal, P.K., E-mail: pkgoyal2002@gmail.com}
abstractNote = {In the era of expanding nuclear energy program all over world, the role of radiation biology has acquired greater relevance and significance in addressing the health and environment issues. In view of constant human exposure to background radiation both naturally and man made e.g nuclear power plants and weapons testing, consumer products, medical X-ray, uranium mining and milling etc., the radiobiological research has been devoted to induction of cancer and evaluation of genetic effects. In the present time, nuclear terrorism and weapon related effects are raising much alarm and concern to public health. Obviously, radiation biology research has great potential in diagnosis, therapy and establishing standards for assessment risk from radiation exposure. The development of effective medical countermeasures to protect, mitigate, and treat normal tissue injury needs urgent investigation for basic molecular mechanisms and developing appropriate ready to-use kits using relevant cellular, animal model and clinical trails for practical purposes. Since the use of synthetic compounds is associated with the inherent toxicity, attention in recent years has been directed towards developing radiation countermeasure agents from the natural sources and/or nature-identical molecules. The rich biodiversity available in the Indian subcontinent has yielded several new drugs that find application in the modern medicine and there is a like hood of discovering many more, Over the last few years, interest in evaluating oriental medicinal herbs and edible phyto products for the use in anti-radiation strategies is encouraging and emerging as an acceptable approach for preventing the radiation induced lesions in many countries. Several Indian medicinal plants (Emblica officinalis, Rosemarinus officinalis, Trigonella foenum-graecum, Alstonia scholaris, Tinospora cordifolia, Phyllanthus niruri, Svzvgiumcumini, Aegle marmelos etc) and antioxidant vitamins (C and E) have been tested in this laboratory by taking various biological end points for the possible use of natural products and phytochemicals to serve as radio protectors for medical countermeasures against radiation injuries, and the results obtained from such studies are highly encouraging and fruitful. It opens new avenues for the application of natural products against planned and unplanned radiation exposure. (author)}
place = {India}
year = {2013}
month = {Oct}
}