Abstract
The aim of this management outcome study was to assess the safety of ventilation/perfusion single photon emission computed tomography (V/Q SPECT) for the diagnosis of pulmonary embolism (PE) using for interpretation the criteria proposed in the European Association of Nuclear Medicine (EANM) guidelines for V/Q scintigraphy. A total of 393 patients with clinically suspected PE referred to the Nuclear Medicine Department of Brest University Hospital from April 2011 to March 2013, with either a high clinical probability or a low or intermediate clinical probability but positive D-dimer, were retrospectively analysed. V/Q SPECT were interpreted by the attending nuclear medicine physician using a diagnostic cut-off of one segmental or two subsegmental mismatches. The final diagnostic conclusion was established by the physician responsible for patient care, based on clinical symptoms, laboratory test, V/Q SPECT and other imaging procedures performed. Patients in whom PE was deemed absent were not treated with anticoagulants and were followed up for 3 months. Of the 393 patients, the prevalence of PE was 28 %. V/Q SPECT was positive for PE in 110 patients (28 %) and negative in 283 patients (72 %). Of the 110 patients with a positive V/Q SPECT, 78 (71 %) had at least
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Le Roux, Pierre-Yves;
Palard, Xavier;
Robin, Philippe;
Abgral, Ronan;
Querellou, Solene;
Salaun, Pierre-Yves;
[1]
Universite de Brest, Brest (France);
CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)];
Delluc, Aurelien;
Couturaud, Francis;
[1]
Universite de Brest, Brest (France);
CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)];
Le Gal, Gregoire;
[1]
University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada);
CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France);
Universite de Brest, Brest (France)]
- Universite Europeenne de Bretagne, Brest (France)
Citation Formats
Le Roux, Pierre-Yves, Palard, Xavier, Robin, Philippe, Abgral, Ronan, Querellou, Solene, Salaun, Pierre-Yves, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)], Delluc, Aurelien, Couturaud, Francis, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)], Le Gal, Gregoire, University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France), and Universite de Brest, Brest (France)].
Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis.
Germany: N. p.,
2014.
Web.
doi:10.1007/S00259-014-2763-1.
Le Roux, Pierre-Yves, Palard, Xavier, Robin, Philippe, Abgral, Ronan, Querellou, Solene, Salaun, Pierre-Yves, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)], Delluc, Aurelien, Couturaud, Francis, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)], Le Gal, Gregoire, University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France), & Universite de Brest, Brest (France)].
Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis.
Germany.
https://doi.org/10.1007/S00259-014-2763-1
Le Roux, Pierre-Yves, Palard, Xavier, Robin, Philippe, Abgral, Ronan, Querellou, Solene, Salaun, Pierre-Yves, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)], Delluc, Aurelien, Couturaud, Francis, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)], Le Gal, Gregoire, University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France), and Universite de Brest, Brest (France)].
2014.
"Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis."
Germany.
https://doi.org/10.1007/S00259-014-2763-1.
@misc{etde_22284244,
title = {Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis}
author = {Le Roux, Pierre-Yves, Palard, Xavier, Robin, Philippe, Abgral, Ronan, Querellou, Solene, Salaun, Pierre-Yves, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)], Delluc, Aurelien, Couturaud, Francis, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)], Le Gal, Gregoire, University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France), and Universite de Brest, Brest (France)]}
abstractNote = {The aim of this management outcome study was to assess the safety of ventilation/perfusion single photon emission computed tomography (V/Q SPECT) for the diagnosis of pulmonary embolism (PE) using for interpretation the criteria proposed in the European Association of Nuclear Medicine (EANM) guidelines for V/Q scintigraphy. A total of 393 patients with clinically suspected PE referred to the Nuclear Medicine Department of Brest University Hospital from April 2011 to March 2013, with either a high clinical probability or a low or intermediate clinical probability but positive D-dimer, were retrospectively analysed. V/Q SPECT were interpreted by the attending nuclear medicine physician using a diagnostic cut-off of one segmental or two subsegmental mismatches. The final diagnostic conclusion was established by the physician responsible for patient care, based on clinical symptoms, laboratory test, V/Q SPECT and other imaging procedures performed. Patients in whom PE was deemed absent were not treated with anticoagulants and were followed up for 3 months. Of the 393 patients, the prevalence of PE was 28 %. V/Q SPECT was positive for PE in 110 patients (28 %) and negative in 283 patients (72 %). Of the 110 patients with a positive V/Q SPECT, 78 (71 %) had at least one additional imaging test (computed tomography pulmonary angiography or ultrasound) and the diagnosis of PE was eventually excluded in one patient. Of the 283 patients with a negative V/Q SPECT, 74 (26 %) patients had another test. The diagnosis of PE was finally retained in one patient and excluded in 282 patients. The 3-month thromboembolic risk in the patients not treated with anticoagulants was 1/262: 0.38 % (95 % confidence interval 0.07-2.13). A diagnostic management including V/Q SPECT interpreted with a diagnostic cut-off of ''one segmental or two subsegmental mismatches'' appears safe to exclude PE. (orig.)}
doi = {10.1007/S00259-014-2763-1}
journal = []
issue = {10}
volume = {41}
journal type = {AC}
place = {Germany}
year = {2014}
month = {Oct}
}
title = {Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis}
author = {Le Roux, Pierre-Yves, Palard, Xavier, Robin, Philippe, Abgral, Ronan, Querellou, Solene, Salaun, Pierre-Yves, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Service de medecine nucleaire, Brest (France)], Delluc, Aurelien, Couturaud, Francis, Universite de Brest, Brest (France), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France)], Le Gal, Gregoire, University of Ottawa, Ottawa Hospital Research Institute, Ottawa (Canada), CHRU de la Cavale Blanche, Departement de medecine interne et de pneumologie, Brest (France), and Universite de Brest, Brest (France)]}
abstractNote = {The aim of this management outcome study was to assess the safety of ventilation/perfusion single photon emission computed tomography (V/Q SPECT) for the diagnosis of pulmonary embolism (PE) using for interpretation the criteria proposed in the European Association of Nuclear Medicine (EANM) guidelines for V/Q scintigraphy. A total of 393 patients with clinically suspected PE referred to the Nuclear Medicine Department of Brest University Hospital from April 2011 to March 2013, with either a high clinical probability or a low or intermediate clinical probability but positive D-dimer, were retrospectively analysed. V/Q SPECT were interpreted by the attending nuclear medicine physician using a diagnostic cut-off of one segmental or two subsegmental mismatches. The final diagnostic conclusion was established by the physician responsible for patient care, based on clinical symptoms, laboratory test, V/Q SPECT and other imaging procedures performed. Patients in whom PE was deemed absent were not treated with anticoagulants and were followed up for 3 months. Of the 393 patients, the prevalence of PE was 28 %. V/Q SPECT was positive for PE in 110 patients (28 %) and negative in 283 patients (72 %). Of the 110 patients with a positive V/Q SPECT, 78 (71 %) had at least one additional imaging test (computed tomography pulmonary angiography or ultrasound) and the diagnosis of PE was eventually excluded in one patient. Of the 283 patients with a negative V/Q SPECT, 74 (26 %) patients had another test. The diagnosis of PE was finally retained in one patient and excluded in 282 patients. The 3-month thromboembolic risk in the patients not treated with anticoagulants was 1/262: 0.38 % (95 % confidence interval 0.07-2.13). A diagnostic management including V/Q SPECT interpreted with a diagnostic cut-off of ''one segmental or two subsegmental mismatches'' appears safe to exclude PE. (orig.)}
doi = {10.1007/S00259-014-2763-1}
journal = []
issue = {10}
volume = {41}
journal type = {AC}
place = {Germany}
year = {2014}
month = {Oct}
}