Abstract
Purpose: To determine the recurrent nodal gross tumor volume (rnGTV) based on CT-guided vascular structure to refine the clinical target volume (CTV) delineation in postoperative radiotherapy for advanced gastric cancer following radical gastrectomy with D2 dissection. Materials and methods: We retrospectively reviewed follow-up images from 91 patients with their first regional recurrence after D2 dissection in stage III gastric cancer with N3 disease. We defined rnGTV as recurrent nodes shown in follow-up CT images, in which one diagnostic radiologist with specialty of gastrointestinal tract investigated. We drew rnGTVs at the equivalent location based on the same vessels of reference comparing CT images to recurrence CT images. Results: We propose vessel-based locations of rnGTVs on CT images with axial and coronal views. We show different patterns of regional recurrence according to the location of primary gastric cancer using CT and digitally reconstructed radiograph (DRR) images. Frequently recurred sites, overlapped by more than five rnGTVs, are depicted in a DRR image. Conclusions: This study suggests vessel-based delineations of rnGTVs on CT images depending on nodal recurrence sites from follow-up images after D2 lymphadenectomy. Our results could help reduce the inter-observer variation of CTV delineation after D2 dissection in gastric cancer.
Yoon, Hong In;
[1]
Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)];
Chang, Jee Suk;
[1]
Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac;
[2]
Noh, Sung Hoon;
Hyung, Woo Jin;
An, Ji Yeong;
[3]
Lee, Yong Chan;
Rha, Sun Young;
[4]
Kim, Kyung Hwan;
[1]
Koom, Woong Sub, E-mail: mdgold@yuhs.ac
[1]
- Department of Radiation Oncology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)
- Department of Radiology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)
- Department of Surgery, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)
- Department of Internal Medicine, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)
Citation Formats
Yoon, Hong In, Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)], Chang, Jee Suk, Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac, Noh, Sung Hoon, Hyung, Woo Jin, An, Ji Yeong, Lee, Yong Chan, Rha, Sun Young, Kim, Kyung Hwan, and Koom, Woong Sub, E-mail: mdgold@yuhs.ac.
Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation.
Ireland: N. p.,
2013.
Web.
doi:10.1016/J.RADONC.2013.05.025.
Yoon, Hong In, Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)], Chang, Jee Suk, Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac, Noh, Sung Hoon, Hyung, Woo Jin, An, Ji Yeong, Lee, Yong Chan, Rha, Sun Young, Kim, Kyung Hwan, & Koom, Woong Sub, E-mail: mdgold@yuhs.ac.
Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation.
Ireland.
https://doi.org/10.1016/J.RADONC.2013.05.025
Yoon, Hong In, Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)], Chang, Jee Suk, Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac, Noh, Sung Hoon, Hyung, Woo Jin, An, Ji Yeong, Lee, Yong Chan, Rha, Sun Young, Kim, Kyung Hwan, and Koom, Woong Sub, E-mail: mdgold@yuhs.ac.
2013.
"Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation."
Ireland.
https://doi.org/10.1016/J.RADONC.2013.05.025.
@misc{etde_22267029,
title = {Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation}
author = {Yoon, Hong In, Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)], Chang, Jee Suk, Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac, Noh, Sung Hoon, Hyung, Woo Jin, An, Ji Yeong, Lee, Yong Chan, Rha, Sun Young, Kim, Kyung Hwan, and Koom, Woong Sub, E-mail: mdgold@yuhs.ac}
abstractNote = {Purpose: To determine the recurrent nodal gross tumor volume (rnGTV) based on CT-guided vascular structure to refine the clinical target volume (CTV) delineation in postoperative radiotherapy for advanced gastric cancer following radical gastrectomy with D2 dissection. Materials and methods: We retrospectively reviewed follow-up images from 91 patients with their first regional recurrence after D2 dissection in stage III gastric cancer with N3 disease. We defined rnGTV as recurrent nodes shown in follow-up CT images, in which one diagnostic radiologist with specialty of gastrointestinal tract investigated. We drew rnGTVs at the equivalent location based on the same vessels of reference comparing CT images to recurrence CT images. Results: We propose vessel-based locations of rnGTVs on CT images with axial and coronal views. We show different patterns of regional recurrence according to the location of primary gastric cancer using CT and digitally reconstructed radiograph (DRR) images. Frequently recurred sites, overlapped by more than five rnGTVs, are depicted in a DRR image. Conclusions: This study suggests vessel-based delineations of rnGTVs on CT images depending on nodal recurrence sites from follow-up images after D2 lymphadenectomy. Our results could help reduce the inter-observer variation of CTV delineation after D2 dissection in gastric cancer.}
doi = {10.1016/J.RADONC.2013.05.025}
journal = []
issue = {1}
volume = {108}
journal type = {AC}
place = {Ireland}
year = {2013}
month = {Jul}
}
title = {Defining the target volume for post-operative radiotherapy after D2 dissection in gastric cancer by CT-based vessel-guided delineation}
author = {Yoon, Hong In, Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul (Korea, Republic of)], Chang, Jee Suk, Lim, Joon Seok, E-mail: JSLIM1@yuhs.ac, Noh, Sung Hoon, Hyung, Woo Jin, An, Ji Yeong, Lee, Yong Chan, Rha, Sun Young, Kim, Kyung Hwan, and Koom, Woong Sub, E-mail: mdgold@yuhs.ac}
abstractNote = {Purpose: To determine the recurrent nodal gross tumor volume (rnGTV) based on CT-guided vascular structure to refine the clinical target volume (CTV) delineation in postoperative radiotherapy for advanced gastric cancer following radical gastrectomy with D2 dissection. Materials and methods: We retrospectively reviewed follow-up images from 91 patients with their first regional recurrence after D2 dissection in stage III gastric cancer with N3 disease. We defined rnGTV as recurrent nodes shown in follow-up CT images, in which one diagnostic radiologist with specialty of gastrointestinal tract investigated. We drew rnGTVs at the equivalent location based on the same vessels of reference comparing CT images to recurrence CT images. Results: We propose vessel-based locations of rnGTVs on CT images with axial and coronal views. We show different patterns of regional recurrence according to the location of primary gastric cancer using CT and digitally reconstructed radiograph (DRR) images. Frequently recurred sites, overlapped by more than five rnGTVs, are depicted in a DRR image. Conclusions: This study suggests vessel-based delineations of rnGTVs on CT images depending on nodal recurrence sites from follow-up images after D2 lymphadenectomy. Our results could help reduce the inter-observer variation of CTV delineation after D2 dissection in gastric cancer.}
doi = {10.1016/J.RADONC.2013.05.025}
journal = []
issue = {1}
volume = {108}
journal type = {AC}
place = {Ireland}
year = {2013}
month = {Jul}
}