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Acute hepatic encephalopathy presenting as cortical laminar necrosis: Case report

Abstract

We report on a 55-year-old man with alcoholic liver cirrhosis who presented with status epilepticus. Laboratory analysis showed markedly elevated blood ammonia. Brain magnetic resonance imaging (MRI) showed widespread cortical signal changes with restricted diffusion, involving both temporo-fronto-parietal cortex, while the perirolandic regions and occipital cortex were uniquely spared. A follow-up brain MRI demonstrated diffuse cortical atrophy with increased signals on T1-weighted images in both the basal ganglia and temporal lobe cortex, representing cortical laminar necrosis. We suggest that the brain lesions, in our case, represent a consequence of toxic effect of ammonia.
Authors:
Choi, Jong Mun; Kim, Yoon Hee; Roh, Sook Young [1] 
  1. Bundang Jesaeng General Hospital, Daejin Medical Center, Seongnam (Korea, Republic of)
Publication Date:
Apr 15, 2013
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Radiology; Journal Volume: 14; Journal Issue: 2; Other Information: 10 refs, 1 fig
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AMMONIA; BRAIN; LIVER CIRRHOSIS; LUNGS; NECROSIS; NMR IMAGING; SIGNALS
OSTI ID:
22248466
Country of Origin:
Korea, Republic of
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1229-6929; TRN: KR1402338069614
Submitting Site:
KRN
Size:
page(s) 324-328
Announcement Date:
Jul 11, 2014

Citation Formats

Choi, Jong Mun, Kim, Yoon Hee, and Roh, Sook Young. Acute hepatic encephalopathy presenting as cortical laminar necrosis: Case report. Korea, Republic of: N. p., 2013. Web. doi:10.3348/kjr.2013.14.2.324.
Choi, Jong Mun, Kim, Yoon Hee, & Roh, Sook Young. Acute hepatic encephalopathy presenting as cortical laminar necrosis: Case report. Korea, Republic of. doi:10.3348/kjr.2013.14.2.324.
Choi, Jong Mun, Kim, Yoon Hee, and Roh, Sook Young. 2013. "Acute hepatic encephalopathy presenting as cortical laminar necrosis: Case report." Korea, Republic of. doi:10.3348/kjr.2013.14.2.324. https://www.osti.gov/servlets/purl/10.3348/kjr.2013.14.2.324.
@misc{etde_22248466,
title = {Acute hepatic encephalopathy presenting as cortical laminar necrosis: Case report}
author = {Choi, Jong Mun, Kim, Yoon Hee, and Roh, Sook Young}
abstractNote = {We report on a 55-year-old man with alcoholic liver cirrhosis who presented with status epilepticus. Laboratory analysis showed markedly elevated blood ammonia. Brain magnetic resonance imaging (MRI) showed widespread cortical signal changes with restricted diffusion, involving both temporo-fronto-parietal cortex, while the perirolandic regions and occipital cortex were uniquely spared. A follow-up brain MRI demonstrated diffuse cortical atrophy with increased signals on T1-weighted images in both the basal ganglia and temporal lobe cortex, representing cortical laminar necrosis. We suggest that the brain lesions, in our case, represent a consequence of toxic effect of ammonia.}
doi = {10.3348/kjr.2013.14.2.324}
journal = {Korean Journal of Radiology}
issue = {2}
volume = {14}
journal type = {AC}
place = {Korea, Republic of}
year = {2013}
month = {Apr}
}