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Studies on the Cold Incubation Method in the {sup 131}I-T3 Resin Sponge Uptake Test

Abstract

An attempt was made to establish a new method that eliminates the correction factors in incubation time and temperature of T3 resin sponge uptake test. Each pooled serum in three different states of thyroid function, i.e. hyperthyroid, euthyroid and hypothyroid,was separately incubated for 20, 24 and 28 h with T3 resin sponge either in a cold room at 2 Degree-Sign C, 5 Degree-Sign C or 8 Degree-Sign C, or in a refrigerator adjusted to 5 Degree-Sign C. The T3 uptake values in each pooled serum were not affected by the difference in the temperature and the incubation time in the cold incubation method. Applicability of the present method (using refrigerator) was examined in about 200 cases of different states of thyroid function. The values obtained by the strictly controlled conventional method (25 Degree-Sign C, 1 h) showed a good correlation with those obtained by the new method. In cases of hypothyroidal state the present method yielded a wider range of uptake values than the conventional one, and hence provided a better method of distinguishing thyroidal function. (author)
Authors:
Tsuchiya, T.; [1]  Takino, H.; Kurata, K.; Wakebayashi, T.; [2]  Ito, K.; Nishikawa, T.; Ino, E.; [3]  Momotani, N. [4] 
  1. National Institute of Radiological Sciences, Chiba (Japan)
  2. Dainabot Radioisotope Laboratory, Ltd, Tokyo (Japan)
  3. Ito Hospital, Tokyo (Japan)
  4. Dept. of Internal Medicine, Keio University Medical School, Tokyo (Japan)
Publication Date:
Feb 15, 1970
Product Type:
Conference
Report Number:
IAEA-SM-124/58
Resource Relation:
Conference: Symposium on In Vitro Procedures with Radioisotopes in Clinical Medicine and Research, Vienna (Austria), 8-12 Sep 1969; Other Information: 3 refs., 8 figs., 1 tab.; Related Information: In: In Vitro Procedures with Radioisotopes in Medicine. Proceedings of the Symposium on In Vitro Procedures with Radioistopes in Clinical Medicine and Research| 736 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSTIC TECHNIQUES; DIAGNOSTIC USES; INCUBATION; IODINE 131; RADIOPHARMACEUTICALS; RESINS; THYROID; UPTAKE
OSTI ID:
22205114
Research Organizations:
International Atomic Energy Agency, Vienna (Austria); World Health Organization, Geneva (Switzerland)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M4195026026
Submitting Site:
INIS
Size:
page(s) 255-261
Announcement Date:
Mar 17, 2014

Citation Formats

Tsuchiya, T., Takino, H., Kurata, K., Wakebayashi, T., Ito, K., Nishikawa, T., Ino, E., and Momotani, N. Studies on the Cold Incubation Method in the {sup 131}I-T3 Resin Sponge Uptake Test. IAEA: N. p., 1970. Web.
Tsuchiya, T., Takino, H., Kurata, K., Wakebayashi, T., Ito, K., Nishikawa, T., Ino, E., & Momotani, N. Studies on the Cold Incubation Method in the {sup 131}I-T3 Resin Sponge Uptake Test. IAEA.
Tsuchiya, T., Takino, H., Kurata, K., Wakebayashi, T., Ito, K., Nishikawa, T., Ino, E., and Momotani, N. 1970. "Studies on the Cold Incubation Method in the {sup 131}I-T3 Resin Sponge Uptake Test." IAEA.
@misc{etde_22205114,
title = {Studies on the Cold Incubation Method in the {sup 131}I-T3 Resin Sponge Uptake Test}
author = {Tsuchiya, T., Takino, H., Kurata, K., Wakebayashi, T., Ito, K., Nishikawa, T., Ino, E., and Momotani, N.}
abstractNote = {An attempt was made to establish a new method that eliminates the correction factors in incubation time and temperature of T3 resin sponge uptake test. Each pooled serum in three different states of thyroid function, i.e. hyperthyroid, euthyroid and hypothyroid,was separately incubated for 20, 24 and 28 h with T3 resin sponge either in a cold room at 2 Degree-Sign C, 5 Degree-Sign C or 8 Degree-Sign C, or in a refrigerator adjusted to 5 Degree-Sign C. The T3 uptake values in each pooled serum were not affected by the difference in the temperature and the incubation time in the cold incubation method. Applicability of the present method (using refrigerator) was examined in about 200 cases of different states of thyroid function. The values obtained by the strictly controlled conventional method (25 Degree-Sign C, 1 h) showed a good correlation with those obtained by the new method. In cases of hypothyroidal state the present method yielded a wider range of uptake values than the conventional one, and hence provided a better method of distinguishing thyroidal function. (author)}
place = {IAEA}
year = {1970}
month = {Feb}
}