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Estimation of the Body Content Following Inhalation of Insoluble Plutonium; Evaluation de la Charge Corporelle de Plutonium, a la Suite de l'Inhalation de Plutonium Insoluble; 041e 041f 0420 0415 0414 ; Carga Corporal Consecutiva a la Inhalacion de Plutonio Insoluble

Abstract

The problem of estimating the body content of plutonium following the inhalation of plutonium oxide is of considerable practical importance and, on the grounds of the known insolubility of plutonium oxide, measurements of plutonium in urine might be considered valueless. This paper reviews the relevant published biological data from beagle dog experiments and also reviews data from two human cases. From this review it is concluded that there is evidence for believing that the body content, following an accidental inhalation, can be estimated from the measurements of plutonium excreted in urine at times greater than about 300 d after the intake. Some possible excretion methods are discussed. Finally, there is a comment on the radiological protection aspects of insoluble plutonium in the lungs and bronchial lymph nodes and it is stressed that the particular nature of the plutonium must be taken into consideration. (author) [French] Le probleme de l'evaluation de la charge corporelle de plutonium a la suite de l'inhalation d'oxyde de plutonium presente une grande importance sur l'e plan pratique et, en raison de l'insolubilite bien connue de l'oxyde de plutonium on peut etre tente de considerer comme sans valeur les dosages du plutonium contenu dans l'urine. L'auteur passe  More>>
Authors:
Dolphin, G. W. [1] 
  1. Authority Health and Safety Branch, Radiological Protection Division, United Kingdom Atomic Energy Authority, Harwell, Berks. (United Kingdom)
Publication Date:
Nov 15, 1964
Product Type:
Conference
Report Number:
IAEA-SM-52/11
Resource Relation:
Conference: Symposium on the Assessment of Radioactive Body Burdens, Heidelberg (Germany), 11-16 May 1964; Other Information: 21 refs., 4 tabs., 2 figs.; Related Information: In: Assessment of Radioactivity in Man. Vol. II. Proceedings of the Symposium on the Assessment of Radioactive Body Burdens| 671 p.
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; 63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BEAGLES; BODY BURDEN; EXCRETION; HUMAN POPULATIONS; INHALATION; LUNGS; LYMPH NODES; PERSONNEL MONITORING; PLUTONIUM; PLUTONIUM OXIDES; RADIATION PROTECTION; RADIONUCLIDE KINETICS; REVIEWS; URINE
OSTI ID:
22200076
Research Organizations:
International Atomic Energy Agency, Vienna (Austria); International Labour Organisation, Geneva (Switzerland); World Health Organization, Geneva (Switzerland)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M3282020899
Submitting Site:
INIS
Size:
page(s) 589-602
Announcement Date:
Feb 27, 2014

Citation Formats

Dolphin, G. W. Estimation of the Body Content Following Inhalation of Insoluble Plutonium; Evaluation de la Charge Corporelle de Plutonium, a la Suite de l'Inhalation de Plutonium Insoluble; 041e 041f 0420 0415 0414 ; Carga Corporal Consecutiva a la Inhalacion de Plutonio Insoluble. IAEA: N. p., 1964. Web.
Dolphin, G. W. Estimation of the Body Content Following Inhalation of Insoluble Plutonium; Evaluation de la Charge Corporelle de Plutonium, a la Suite de l'Inhalation de Plutonium Insoluble; 041e 041f 0420 0415 0414 ; Carga Corporal Consecutiva a la Inhalacion de Plutonio Insoluble. IAEA.
Dolphin, G. W. 1964. "Estimation of the Body Content Following Inhalation of Insoluble Plutonium; Evaluation de la Charge Corporelle de Plutonium, a la Suite de l'Inhalation de Plutonium Insoluble; 041e 041f 0420 0415 0414 ; Carga Corporal Consecutiva a la Inhalacion de Plutonio Insoluble." IAEA.
@misc{etde_22200076,
title = {Estimation of the Body Content Following Inhalation of Insoluble Plutonium; Evaluation de la Charge Corporelle de Plutonium, a la Suite de l'Inhalation de Plutonium Insoluble; 041e 041f 0420 0415 0414 ; Carga Corporal Consecutiva a la Inhalacion de Plutonio Insoluble}
author = {Dolphin, G. W.}
abstractNote = {The problem of estimating the body content of plutonium following the inhalation of plutonium oxide is of considerable practical importance and, on the grounds of the known insolubility of plutonium oxide, measurements of plutonium in urine might be considered valueless. This paper reviews the relevant published biological data from beagle dog experiments and also reviews data from two human cases. From this review it is concluded that there is evidence for believing that the body content, following an accidental inhalation, can be estimated from the measurements of plutonium excreted in urine at times greater than about 300 d after the intake. Some possible excretion methods are discussed. Finally, there is a comment on the radiological protection aspects of insoluble plutonium in the lungs and bronchial lymph nodes and it is stressed that the particular nature of the plutonium must be taken into consideration. (author) [French] Le probleme de l'evaluation de la charge corporelle de plutonium a la suite de l'inhalation d'oxyde de plutonium presente une grande importance sur l'e plan pratique et, en raison de l'insolubilite bien connue de l'oxyde de plutonium on peut etre tente de considerer comme sans valeur les dosages du plutonium contenu dans l'urine. L'auteur passe en revue les donnees biologiques pertinentes deja publiees a la suite d'experiences faites sur les chiens bigles, ainsi que des donnees relatives a deux cas d'inhalation par des hommes. D'apres cette etude, il y a lieu de croire qu'on peut evaluer la charge corporelle de plutonium, a la suite d'une inhalation accidentelle, en faisant des dosages du plutonium contenu dans l'urine plus de 300 jours apres l'absorption. Il discute plusieurs methodes possibles. Il examine, enfin, sous l'angle de la protection radiologique, la presence du plutonium insoluble dans les poumons et les ganglions lymphatiques des bronches et il insiste sur le fait qu'il faut tenir compte de la nature particuliere du plutonium. (author) [Spanish] El problema de calcular la carga corporal de plutonio despues de haber inhalado oxido de plutonio tiene considerable importancia practica y, debido a que el oxido de plutonio es insoluble, no se pueden considerar validas las determinaciones de plutonio en la orina. La memoria revisa los datos biologicos publicados acerca de experimentos con sabuesos y, en dos casos, con seres humanos. De estos datos se deduce que existen razones para creer que la carga corporal derivada de la inhalacion accidental se puede calcular a partir de mediciones del plutonio excretado por la orina, pasados mas de unos 300 dias desde la absorcion. La memoria discute algunas de las posibles vias de excrecion. Por ultimo, comenta la presencia de plutonio insoluble en los pulmones y en los nodulos linfaticos de los bronquios desde el punto de vista de la proteccion radiologica y destaca la necesidad de tener en cuenta el hecho de que el plutonio se encuentra en forma de particulas. (author) [Russian] Problema opredelenija soderzhanija plutonija v organizme cheloveka posle vdyhanija okisi plutonija predstavljaet soboj bol'shoe prakticheskoe znachenie, i v silu izvestnoj nerastvorimosti okisi plutonija izmerenija plutonija v moche mogut schitat'sja ochen' cennymi. Rassmatrivajutsja otnosjashhiesja k jetomu voprosu opublikovannye biologicheskie dannye, poluchennye v opytah na gonchih sobakah, a takzhe na ljudjah. Sdelan vyvod, chto soderzhanie plutonija v organizme cheloveka posle sluchajnogo vdyhanija mozhno opredelit' putem izmerenij plutonija, vydelennogo s mochoj inogda spustja bolee 300 dnej s momenta pogloshhenija. Obsuzhdajutsja nekotorye vozmozhnye metody vydelenija. Nakonec, dajutsja kommentarii k aspektam radiologicheskoj zashity v otnoshenii nerastvorimogo plutonija v legkih i v bronhial'nyh limfaticheskih uzlah, i podcherkivaetsja, chto sleduet prinimat' vo vnimanie specificheskij harakter plutonija. (author)}
place = {IAEA}
year = {1964}
month = {Nov}
}