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Half-Life Studies of Radiocaesium in Humans; Etudes sur la Periode de Radiocesium chez l'Homme; 0418 0421 0421 041b 0415 0414 ; Estudio sobre el Periodo Biologico del Radiocesio en el Hombre

Abstract

The retention of caesium-137 in humans has been studied in several cases. Two adult men were intravenously administered a small quantity of caesium-137. They were followed about 300 days by frequent whole-body counting and with excreta collection during the initial period. The retention decreased as a sum of two exponentials. The slowest compartment decreased with a half-life of about 75 d. One of them was also given caesium-137 orally 2 years later with the same excretion pattern obtained as after intravenous injection. The excretion rate of caesium-137 has also been studied in a different way for large groups of men, women and children through comparison with diet data. From a group of 10 people, voluntarily changing their diet, the average excretion rate could be calculated from whole-body counting at an interval of six weeks. The excretion also has been obtained from a study on two people after an oral administration of caesium-132. Detailed results on these studies will be given particularly with respect to the elimination rate of caesium, i.e. the biological half-life and its variation with sex and age. On the average, half-lives ranging from 30 to 90 d have been obtained. (author) [French] La retention de cesium 137  More>>
Authors:
Naversten, Y.; Liden, K. [1] 
  1. Radiation Physics Department, University of Lund (Sweden)
Publication Date:
Nov 15, 1964
Product Type:
Conference
Report Number:
IAEA-SM-52/50
Resource Relation:
Conference: Symposium on the Assessment of Radioactive Body Burdens, Heidelberg (Germany), 11-16 May 1964; Other Information: 9 refs., 2 figs., 5 tabs.; Related Information: In: Assessment of Radioactivity in Man. Vol. II. Proceedings of the Symposium on the Assessment of Radioactive Body Burdens| 671 p.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BIOLOGICAL HALF-LIFE; BODY BURDEN; CESIUM; CESIUM 137; CHILDREN; DIET; EXCRETION; INTRAVENOUS INJECTION; ORAL ADMINISTRATION; PERSONNEL MONITORING; RADIONUCLIDE KINETICS; RETENTION; WHOLE-BODY COUNTING; WOMEN
OSTI ID:
22200040
Research Organizations:
International Atomic Energy Agency, Vienna (Austria); International Labour Organisation, Geneva (Switzerland); World Health Organization, Geneva (Switzerland)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M3246020863
Submitting Site:
INIS
Size:
page(s) 79-87
Announcement Date:
Feb 27, 2014

Citation Formats

Naversten, Y., and Liden, K. Half-Life Studies of Radiocaesium in Humans; Etudes sur la Periode de Radiocesium chez l'Homme; 0418 0421 0421 041b 0415 0414 ; Estudio sobre el Periodo Biologico del Radiocesio en el Hombre. IAEA: N. p., 1964. Web.
Naversten, Y., & Liden, K. Half-Life Studies of Radiocaesium in Humans; Etudes sur la Periode de Radiocesium chez l'Homme; 0418 0421 0421 041b 0415 0414 ; Estudio sobre el Periodo Biologico del Radiocesio en el Hombre. IAEA.
Naversten, Y., and Liden, K. 1964. "Half-Life Studies of Radiocaesium in Humans; Etudes sur la Periode de Radiocesium chez l'Homme; 0418 0421 0421 041b 0415 0414 ; Estudio sobre el Periodo Biologico del Radiocesio en el Hombre." IAEA.
@misc{etde_22200040,
title = {Half-Life Studies of Radiocaesium in Humans; Etudes sur la Periode de Radiocesium chez l'Homme; 0418 0421 0421 041b 0415 0414 ; Estudio sobre el Periodo Biologico del Radiocesio en el Hombre}
author = {Naversten, Y., and Liden, K.}
abstractNote = {The retention of caesium-137 in humans has been studied in several cases. Two adult men were intravenously administered a small quantity of caesium-137. They were followed about 300 days by frequent whole-body counting and with excreta collection during the initial period. The retention decreased as a sum of two exponentials. The slowest compartment decreased with a half-life of about 75 d. One of them was also given caesium-137 orally 2 years later with the same excretion pattern obtained as after intravenous injection. The excretion rate of caesium-137 has also been studied in a different way for large groups of men, women and children through comparison with diet data. From a group of 10 people, voluntarily changing their diet, the average excretion rate could be calculated from whole-body counting at an interval of six weeks. The excretion also has been obtained from a study on two people after an oral administration of caesium-132. Detailed results on these studies will be given particularly with respect to the elimination rate of caesium, i.e. the biological half-life and its variation with sex and age. On the average, half-lives ranging from 30 to 90 d have been obtained. (author) [French] La retention de cesium 137 chez l'homme a ete etudiee sur plusieurs sujets. Ainsi, on a administre a deux hommes adultes, par voie intraveineuse, une petite quantite de cesium 137. On les a suivis pendant 300 j environ en faisant de frequents dosages de l'activite du corps et en recueillant les excreta au debut de la periode. La fonction qui representait la decroissance de la retention est une somme de deux exponentielles. La fraction qui decroissait le plus lentement avait une periode d'environ 75 j. Deux ans plus tard, on a administre du cesium 137 a un des deux sujets, par voie buccale, et on a obtenu le meme regime d'elimination qu'apres l'injection intraveineuse. On a aussi etudie le taux d'elimination de cesium 137 par une methode differente pour des groupes importants d'hommes/ de femmes et d'enfants en faisant des comparaisons avec des donnees concernant leur regime alimentaire. Pour un groupe de dix personnes qui avaient volontairement accepte un changement de leur regime-alimentaire, on a pu calculer le taux d'elimination moyen en procedant a des dosages de l'activite du corps a des intervalles de six semaines. On a aussi obtenu ce taux pour deux personnes auxquelles on avait administre du cesium 132 par voie buccale. Les auteurs communiquent les resultats detailles de ces etudes, notamment en ce qui concerne le taux d'elimination du cesium, c'est-a-dire la periode biologique et ses variations selon le sexe et l'age. Dans l'ensemble, on a trouve des periodes allant de 30 a 90 j. (author) [Spanish] Se ha estudiado en varios casos la retencion de cesio-137 en los seres humanos. A tal efecto, se administro por via intravenosa una pequefla cantidad de cesio-137 a dos adultos que permanecieron en observacion durante unos 300 dias, practicandoseles frecuentes examenes antropogammametricos, combinados con recogida de excreciones durante el periodo inicial. La retencion disminuyo segun la suma de dos funciones exponenciales. El compartimiento mas lento decrecio con un periodo biologico de unos 75 d. Ademas, a una de las dos personas mencionadas se le administro dos aflos mas tarde cesio-137 por via oral, siendo la eliminacion por excrecion analoga a la observada a rafz de la inyeccion intravenosa. Asimismo, se ha estudiado por un procedimiento diferente (comparacion con los valores de la dieta) la velocidad de excrecion del cesio-137 en grandes grupos de hombres, mujeres y ninos. Se ha calculado por antropogammametria la velocidad media de excrecion, en un intervalo de seis semanas, de un grupo de diez personas que modificaron su dieta voluntariamente. Tambien se ha determinado la velocidad de eliminacion por excrecion en dos personas a las que se habia administrado cesio-132 por via oral. Se exponen los resultados detallados de estos estudios, sobre todo en lo que respecta a la velocidad de eliminacion del cesio, es decir, al periodo biologico y a su variacion segun el sexo y la edad. Por lo general, los periodos biologicos determinados experimentalmente oscilan entre 30 y 90 d. (author) [Russian] Izuchalas zaderzhka cezija-137 u ljudej pri razlichnyh obstojatel'stvah. Dvum vzroslym muzhchinam vvodili vnutrivenno malye kolichestva cezija-137. Pacienty nahodilis' pod nabljudeniem 300 dnej, v techenie kotoryh proizvodilis' chastye izmerenija radio aktivnosti vsego organizma.i sbor vydelenij v nachal'nom periode. Stepen' zaderzhki izotopa snizhalas' kak summa dvuh jeksponencial'nyh velichin. Naibolee medlenno izmenjajushhajasja velichina snizhalas' s periodom poluvyvedenija okolo 75 dnej. Olin iz pacientov poluchal cezij-137 vnutr' 2 goda spustja,prichem nabljudalsja tot zhe tip vydelenija, kak i posle vnutrivennogo vvedenija. Skorost' vydelenija cezija-137 izuchalas' takzhe drugim sposobom u bol'shoj gruppy muzhchin, zhenshhin i detej putem sravnenija dannyh issledovanija diety. Pri obsledovanii gruppy iz 10 dobrovol'cev, izmenivshih svoju dietu, okazalos' vozmozhnym rasschitat' srednjuju skorost' vydelenija na osnovanii izmerenija radioaktivnosti vsego organizma s intervalom v 6 nedel'. Vydelenija opredeljali takzhe u 2-h chelovek posle priema vnutr' cezija-137. Predstavleny podrobnye dannye jetih issledovanij, v osobennosti v otnoshenii skorosti vydelenija cezija, t.e. perioda ego poluvyvedenija i ego variacij v zavisimosti ot pola i vozrasta. V srednem byli polucheny sroki poluvyvedenija ot 30 do 90 dnej. (author)}
place = {IAEA}
year = {1964}
month = {Nov}
}