Abstract
The experimental data pertaining to the mutagenic efficiency of {sup 32}P in Drosophila are discussed. It is estimated that the efficiency of the transmutation phenomena is of the order of 10{sup -9} to 10{sup -3} for the induction of recessive lethals. It is thus orders of magnitude lower than that found in bacteria and fungi. The efficiency would be lower - in comparison with the radiation effects - in organisms of greater dimensions than Drosophila, where a smaller fraction of dose is lost through the escape from the organism of high-energy {beta}-particles. Data are also reported on the genetic effects of {sup 3}H-thymidine, {sup 3}H-lysine and {sup 3}H-arginine. It appears that in all probability the effects may be interpreted as caused by radiation alone, if due regard is given to variations in radiation sensitivity and cellular dimensions during spermiogenesis. (author)
Oftedal, P.;
Kaplan, W. D.;
[1]
City of Hope Medical Research Center, Duarte, CA (United States)]
- Norsk Hydro Institute for Cancer Research, Oslo (Norway)
Citation Formats
Oftedal, P., Kaplan, W. D., and City of Hope Medical Research Center, Duarte, CA (United States)].
Some Aspects of Transmutation Studies in Drosophila.
IAEA: N. p.,
1968.
Web.
Oftedal, P., Kaplan, W. D., & City of Hope Medical Research Center, Duarte, CA (United States)].
Some Aspects of Transmutation Studies in Drosophila.
IAEA.
Oftedal, P., Kaplan, W. D., and City of Hope Medical Research Center, Duarte, CA (United States)].
1968.
"Some Aspects of Transmutation Studies in Drosophila."
IAEA.
@misc{etde_22190158,
title = {Some Aspects of Transmutation Studies in Drosophila}
author = {Oftedal, P., Kaplan, W. D., and City of Hope Medical Research Center, Duarte, CA (United States)]}
abstractNote = {The experimental data pertaining to the mutagenic efficiency of {sup 32}P in Drosophila are discussed. It is estimated that the efficiency of the transmutation phenomena is of the order of 10{sup -9} to 10{sup -3} for the induction of recessive lethals. It is thus orders of magnitude lower than that found in bacteria and fungi. The efficiency would be lower - in comparison with the radiation effects - in organisms of greater dimensions than Drosophila, where a smaller fraction of dose is lost through the escape from the organism of high-energy {beta}-particles. Data are also reported on the genetic effects of {sup 3}H-thymidine, {sup 3}H-lysine and {sup 3}H-arginine. It appears that in all probability the effects may be interpreted as caused by radiation alone, if due regard is given to variations in radiation sensitivity and cellular dimensions during spermiogenesis. (author)}
place = {IAEA}
year = {1968}
month = {Jun}
}
title = {Some Aspects of Transmutation Studies in Drosophila}
author = {Oftedal, P., Kaplan, W. D., and City of Hope Medical Research Center, Duarte, CA (United States)]}
abstractNote = {The experimental data pertaining to the mutagenic efficiency of {sup 32}P in Drosophila are discussed. It is estimated that the efficiency of the transmutation phenomena is of the order of 10{sup -9} to 10{sup -3} for the induction of recessive lethals. It is thus orders of magnitude lower than that found in bacteria and fungi. The efficiency would be lower - in comparison with the radiation effects - in organisms of greater dimensions than Drosophila, where a smaller fraction of dose is lost through the escape from the organism of high-energy {beta}-particles. Data are also reported on the genetic effects of {sup 3}H-thymidine, {sup 3}H-lysine and {sup 3}H-arginine. It appears that in all probability the effects may be interpreted as caused by radiation alone, if due regard is given to variations in radiation sensitivity and cellular dimensions during spermiogenesis. (author)}
place = {IAEA}
year = {1968}
month = {Jun}
}