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Impact of age, gender and diabetes on serum lipid levels

Journal Article:

Abstract

Objectives:To see the effects of age, gender and diabetes on serum lipid levels. Study type, settings and duration:Cross sectional analytical study conducted at PMRC Research Centre, Fatima Jinnah Medical College,Lahore from Jun-Dec 2011. Materials and Methods: One hundred type 2 diabetes mellitus and equal numbers of gender matched healthy controls were randomly selected for the study. After an overnight fasting, blood specimens were drawn for lipid profile where total cholesterol,high density lipoprotein cholesterol and triglycerides were measured by standard enzymatic endpoint methods and LDL-cholesterol by Friedweld's formula. Statistical analysis was done using SPSS-15. Results Odd ratios of age for total cholesterol (OR 1.198); high density lipoprotein cholesterol (OR 1.144); and low density lipoprotein cholesterol (OR 1.576) revealed that subjects aged 45 years or more had greater risk of having deranged lipid levels. Female gender had higher high density lipoprotein cholesterol (p 0.000); and triglycerides (p 0.001). Odd ratios of men for total cholesterol (OR 0.775); high density lipoprotein cholesterol(OR 0.183); and low density lipoprotein Cholesterol (OR 0.683) illustrated that men were significantly less prone to dyslipidemia than women. Odd ratio of diabetes for high density lipoprotein cholesterol (OR 1.802) suggested that diabetics had 1.8 times more risk of having low  More>>
Authors:
Adnan, M.; Shabbir, I.; Ali, Z.; Ali, S. F.; Rahat, T. [1] 
  1. Fatima Jinnah Medical College, Lahore (Pakistan)
Publication Date:
Jan 15, 2013
Product Type:
Journal Article
Resource Relation:
Journal Name: Pakistan Journal of Medical Research; Journal Volume: 52; Journal Issue: 1
Subject:
60 APPLIED LIFE SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; AGE GROUPS; BLOOD SERUM; CARDIOVASCULAR DISEASES; DIABETES MELLITUS; LIPIDS; SEX DEPENDENCE; TRIGLYCERIDES
OSTI ID:
22161970
Country of Origin:
Pakistan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0030-9842; TRN: PK1300435116402
Submitting Site:
INIS
Size:
page(s) 22-24
Announcement Date:
Nov 28, 2013

Journal Article:

Citation Formats

Adnan, M., Shabbir, I., Ali, Z., Ali, S. F., and Rahat, T. Impact of age, gender and diabetes on serum lipid levels. Pakistan: N. p., 2013. Web.
Adnan, M., Shabbir, I., Ali, Z., Ali, S. F., & Rahat, T. Impact of age, gender and diabetes on serum lipid levels. Pakistan.
Adnan, M., Shabbir, I., Ali, Z., Ali, S. F., and Rahat, T. 2013. "Impact of age, gender and diabetes on serum lipid levels." Pakistan.
@misc{etde_22161970,
title = {Impact of age, gender and diabetes on serum lipid levels}
author = {Adnan, M., Shabbir, I., Ali, Z., Ali, S. F., and Rahat, T.}
abstractNote = {Objectives:To see the effects of age, gender and diabetes on serum lipid levels. Study type, settings and duration:Cross sectional analytical study conducted at PMRC Research Centre, Fatima Jinnah Medical College,Lahore from Jun-Dec 2011. Materials and Methods: One hundred type 2 diabetes mellitus and equal numbers of gender matched healthy controls were randomly selected for the study. After an overnight fasting, blood specimens were drawn for lipid profile where total cholesterol,high density lipoprotein cholesterol and triglycerides were measured by standard enzymatic endpoint methods and LDL-cholesterol by Friedweld's formula. Statistical analysis was done using SPSS-15. Results Odd ratios of age for total cholesterol (OR 1.198); high density lipoprotein cholesterol (OR 1.144); and low density lipoprotein cholesterol (OR 1.576) revealed that subjects aged 45 years or more had greater risk of having deranged lipid levels. Female gender had higher high density lipoprotein cholesterol (p 0.000); and triglycerides (p 0.001). Odd ratios of men for total cholesterol (OR 0.775); high density lipoprotein cholesterol(OR 0.183); and low density lipoprotein Cholesterol (OR 0.683) illustrated that men were significantly less prone to dyslipidemia than women. Odd ratio of diabetes for high density lipoprotein cholesterol (OR 1.802) suggested that diabetics had 1.8 times more risk of having low high density lipoprotein cholesterol. Conclusions: Diabetic females over 45 years of age have significantly high chances of having disturbed or high lipid profile. Policy message:All persons in general and diabetics in particular over the age of 45 years should be screened for dyslipidemia and informed using behavior change communication to prevent disease complications. (author)}
journal = {Pakistan Journal of Medical Research}
issue = {1}
volume = {52}
journal type = {AC}
place = {Pakistan}
year = {2013}
month = {Jan}
}