Abstract
Our research on adverse effects of lead exposures on physical and neurobehavioral health of children aged 6-12 years in 4 villages, labeled as K, M, L, and X, in rural China, was reported in this article. Lead in blood (PbB), urine (PbU), hairs (PbH), and nails (PbN) were measured by graphite furnace atomic absorption spectrometry. Abbreviated Symptom Questionnaire of Conner's instruments and Revised Raven's Standard Progressive Matrices were applied to evaluate childhood attention deficit/hyperactivity disorders (ADHD) and intelligences. Geometric means (SD) of PbB, PbU, PbH and PbN concentrations were 71.2 {mu}g/L (1.56), 11.7 {mu}g/g (1.75), 12.5 {mu}g/g (2.82), and 25.3 {mu}g/g (2.79), respectively. 54 (17.0%) children had PbB levels of {>=} 100 {mu}g/L. Boys, the 6-10 years old, and living in village K were 2.11, 2.48, and 9.16 times, respectively, more likely to be poisoned by lead than girls, aged 11-12 years, and residing in X. 18 (5.7%) and 37 (11.7%) subjects had ADHD and mental retardations, respectively. Inverse relationships between intelligences and natural log transformed PbU and PbH levels were observed with respective odds ratios (95%CI) of 1.79 (1.00-3.22) and 1.46 (1.06-2.03) or 1.28 (1.04-1.58) and 1.73 (1.18-2.52) by binary or ordinal logistic regression modeling. ADHD prevalence was different
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Wang, Q.;
Zhao, H. H.;
[1]
Chen, J. W.;
Gu, K. D.;
Zhang, Y. Z.;
Zhu, Y. X.;
Zhou, Y. K.;
[2]
Ye, L.X., E-mail: yelx2004@163.com
[1]
- Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 (China)
- Minitry of Environmental Protection Key Lab of Environment, Wuhan 430030 (China)
Citation Formats
Wang, Q., Zhao, H. H., Chen, J. W., Gu, K. D., Zhang, Y. Z., Zhu, Y. X., Zhou, Y. K., and Ye, L.X., E-mail: yelx2004@163.com.
Adverse health effects of lead exposure on children and exploration to internal lead indicator.
Netherlands: N. p.,
2009.
Web.
doi:10.1016/J.SCITOTENV.2009.08.038.
Wang, Q., Zhao, H. H., Chen, J. W., Gu, K. D., Zhang, Y. Z., Zhu, Y. X., Zhou, Y. K., & Ye, L.X., E-mail: yelx2004@163.com.
Adverse health effects of lead exposure on children and exploration to internal lead indicator.
Netherlands.
https://doi.org/10.1016/J.SCITOTENV.2009.08.038
Wang, Q., Zhao, H. H., Chen, J. W., Gu, K. D., Zhang, Y. Z., Zhu, Y. X., Zhou, Y. K., and Ye, L.X., E-mail: yelx2004@163.com.
2009.
"Adverse health effects of lead exposure on children and exploration to internal lead indicator."
Netherlands.
https://doi.org/10.1016/J.SCITOTENV.2009.08.038.
@misc{etde_22147841,
title = {Adverse health effects of lead exposure on children and exploration to internal lead indicator}
author = {Wang, Q., Zhao, H. H., Chen, J. W., Gu, K. D., Zhang, Y. Z., Zhu, Y. X., Zhou, Y. K., and Ye, L.X., E-mail: yelx2004@163.com}
abstractNote = {Our research on adverse effects of lead exposures on physical and neurobehavioral health of children aged 6-12 years in 4 villages, labeled as K, M, L, and X, in rural China, was reported in this article. Lead in blood (PbB), urine (PbU), hairs (PbH), and nails (PbN) were measured by graphite furnace atomic absorption spectrometry. Abbreviated Symptom Questionnaire of Conner's instruments and Revised Raven's Standard Progressive Matrices were applied to evaluate childhood attention deficit/hyperactivity disorders (ADHD) and intelligences. Geometric means (SD) of PbB, PbU, PbH and PbN concentrations were 71.2 {mu}g/L (1.56), 11.7 {mu}g/g (1.75), 12.5 {mu}g/g (2.82), and 25.3 {mu}g/g (2.79), respectively. 54 (17.0%) children had PbB levels of {>=} 100 {mu}g/L. Boys, the 6-10 years old, and living in village K were 2.11, 2.48, and 9.16 times, respectively, more likely to be poisoned by lead than girls, aged 11-12 years, and residing in X. 18 (5.7%) and 37 (11.7%) subjects had ADHD and mental retardations, respectively. Inverse relationships between intelligences and natural log transformed PbU and PbH levels were observed with respective odds ratios (95%CI) of 1.79 (1.00-3.22) and 1.46 (1.06-2.03) or 1.28 (1.04-1.58) and 1.73 (1.18-2.52) by binary or ordinal logistic regression modeling. ADHD prevalence was different by gender and age of subjects. PbU, PbH, and PbN related to PbB positively with respective correlation coefficients of 0.530, 0.477, and 0.181. Receiver operating characteristic (ROC) curves of the three measurements reveled areas under curves (AUCs) being 0.829, 0.758, and 0.687, respectively. In conclusion, children had moderate levels of lead exposures in this rural area. Intelligence declines were associated with internal lead levels among children. ROC analysis suggests PbU an internal lead indicator close to PbB.}
doi = {10.1016/J.SCITOTENV.2009.08.038}
journal = []
issue = {23}
volume = {407}
journal type = {AC}
place = {Netherlands}
year = {2009}
month = {Nov}
}
title = {Adverse health effects of lead exposure on children and exploration to internal lead indicator}
author = {Wang, Q., Zhao, H. H., Chen, J. W., Gu, K. D., Zhang, Y. Z., Zhu, Y. X., Zhou, Y. K., and Ye, L.X., E-mail: yelx2004@163.com}
abstractNote = {Our research on adverse effects of lead exposures on physical and neurobehavioral health of children aged 6-12 years in 4 villages, labeled as K, M, L, and X, in rural China, was reported in this article. Lead in blood (PbB), urine (PbU), hairs (PbH), and nails (PbN) were measured by graphite furnace atomic absorption spectrometry. Abbreviated Symptom Questionnaire of Conner's instruments and Revised Raven's Standard Progressive Matrices were applied to evaluate childhood attention deficit/hyperactivity disorders (ADHD) and intelligences. Geometric means (SD) of PbB, PbU, PbH and PbN concentrations were 71.2 {mu}g/L (1.56), 11.7 {mu}g/g (1.75), 12.5 {mu}g/g (2.82), and 25.3 {mu}g/g (2.79), respectively. 54 (17.0%) children had PbB levels of {>=} 100 {mu}g/L. Boys, the 6-10 years old, and living in village K were 2.11, 2.48, and 9.16 times, respectively, more likely to be poisoned by lead than girls, aged 11-12 years, and residing in X. 18 (5.7%) and 37 (11.7%) subjects had ADHD and mental retardations, respectively. Inverse relationships between intelligences and natural log transformed PbU and PbH levels were observed with respective odds ratios (95%CI) of 1.79 (1.00-3.22) and 1.46 (1.06-2.03) or 1.28 (1.04-1.58) and 1.73 (1.18-2.52) by binary or ordinal logistic regression modeling. ADHD prevalence was different by gender and age of subjects. PbU, PbH, and PbN related to PbB positively with respective correlation coefficients of 0.530, 0.477, and 0.181. Receiver operating characteristic (ROC) curves of the three measurements reveled areas under curves (AUCs) being 0.829, 0.758, and 0.687, respectively. In conclusion, children had moderate levels of lead exposures in this rural area. Intelligence declines were associated with internal lead levels among children. ROC analysis suggests PbU an internal lead indicator close to PbB.}
doi = {10.1016/J.SCITOTENV.2009.08.038}
journal = []
issue = {23}
volume = {407}
journal type = {AC}
place = {Netherlands}
year = {2009}
month = {Nov}
}