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A Depth-Focusing Collimator for the Investigation of the Brain Cortex; Collimateur a Focalisation Profonde pour l'Exploration de la Substance Corticale du Cerveau; Kollimator s glubinnoj fokusirovkoj dlya''issledovaniya kory golovnogo mozga; Colimador de Enfoque Profundo para Estudios de la Corteza Cerebral

Conference:

Abstract

A detector is described which consists of a 5-in diam. by 1/2 in thick sodium iodide crystal and a depth-focusing collimator. The collimator was designed initially for use in brain cortical blood-flow investigations using Xe{sup 133} but may be used with other soft gamma-emitting isotopes such as I{sup 125}. The collimator, which is constructed of lead, is 1/2-in thick and is of multichannel design. The focus is at 1.75 cm from the face of the collimator. The response in air to a point source on the central axis of the collimator falls to 10% of the maximum at {+-} 0.75 cm from the focus. The far field response in tissue is considerably better than in air due to high tissue attenuation of the soft gamma radiation. The response of the collimator to a point source in air and inside a skull is presented. The collimator has been used to measure local cortical blood flow in the brain using Xe{sup 133}. However, using I{sup 125}-tagged chemicals, the detection of cortical tumours and haemorrhages is possible using this apparatus. (author) [French] L'auteur decrit un detecteur constitue par un cristal de Nal (125 mm de diametre et 6 mm d'epaisseur) et un collimateur  More>>
Authors:
Glasswestern, H. I. [1] 
  1. Regional Hospital Board, Glasgow (United Kingdom)
Publication Date:
Oct 15, 1964
Product Type:
Conference
Report Number:
IAEA-SM-51/27
Resource Relation:
Conference: Symposium on medical radioisotope scanning, Athens (Greece), 20-24 Apr 1964; Other Information: 9 refs., 7 figs.; Related Information: In: Medical Radioisotope Scanning. Vol. I. Proceedings of the Symposium on Medical Radioisotope Scanning| 574 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ANIMAL TISSUES; BLOOD FLOW; BRAIN; COLLIMATORS; GAMMA RADIATION; HEMORRHAGE; IODINE 125; NAI DETECTORS; NUCLEAR MEDICINE; POINT SOURCES; SKULL; XENON 133
OSTI ID:
22127638
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M3051082717
Submitting Site:
INIS
Size:
page(s) 243-251
Announcement Date:
Sep 12, 2013

Conference:

Citation Formats

Glasswestern, H. I. A Depth-Focusing Collimator for the Investigation of the Brain Cortex; Collimateur a Focalisation Profonde pour l'Exploration de la Substance Corticale du Cerveau; Kollimator s glubinnoj fokusirovkoj dlya''issledovaniya kory golovnogo mozga; Colimador de Enfoque Profundo para Estudios de la Corteza Cerebral. IAEA: N. p., 1964. Web.
Glasswestern, H. I. A Depth-Focusing Collimator for the Investigation of the Brain Cortex; Collimateur a Focalisation Profonde pour l'Exploration de la Substance Corticale du Cerveau; Kollimator s glubinnoj fokusirovkoj dlya''issledovaniya kory golovnogo mozga; Colimador de Enfoque Profundo para Estudios de la Corteza Cerebral. IAEA.
Glasswestern, H. I. 1964. "A Depth-Focusing Collimator for the Investigation of the Brain Cortex; Collimateur a Focalisation Profonde pour l'Exploration de la Substance Corticale du Cerveau; Kollimator s glubinnoj fokusirovkoj dlya''issledovaniya kory golovnogo mozga; Colimador de Enfoque Profundo para Estudios de la Corteza Cerebral." IAEA.
@misc{etde_22127638,
title = {A Depth-Focusing Collimator for the Investigation of the Brain Cortex; Collimateur a Focalisation Profonde pour l'Exploration de la Substance Corticale du Cerveau; Kollimator s glubinnoj fokusirovkoj dlya''issledovaniya kory golovnogo mozga; Colimador de Enfoque Profundo para Estudios de la Corteza Cerebral}
author = {Glasswestern, H. I.}
abstractNote = {A detector is described which consists of a 5-in diam. by 1/2 in thick sodium iodide crystal and a depth-focusing collimator. The collimator was designed initially for use in brain cortical blood-flow investigations using Xe{sup 133} but may be used with other soft gamma-emitting isotopes such as I{sup 125}. The collimator, which is constructed of lead, is 1/2-in thick and is of multichannel design. The focus is at 1.75 cm from the face of the collimator. The response in air to a point source on the central axis of the collimator falls to 10% of the maximum at {+-} 0.75 cm from the focus. The far field response in tissue is considerably better than in air due to high tissue attenuation of the soft gamma radiation. The response of the collimator to a point source in air and inside a skull is presented. The collimator has been used to measure local cortical blood flow in the brain using Xe{sup 133}. However, using I{sup 125}-tagged chemicals, the detection of cortical tumours and haemorrhages is possible using this apparatus. (author) [French] L'auteur decrit un detecteur constitue par un cristal de Nal (125 mm de diametre et 6 mm d'epaisseur) et un collimateur a focalisation profonde. Ce collimateur a ete concu pour etudier le flux sanguin dans la substance corticale du cerveau a l'aide de {sup 133}Xe, mais il peut aussi etre utilise avec d'autres emetteurs de rayons gamma mous, tels que izsi. Le collimateur, a canaux multiples, est en plomb; il a une epaisseur de 6 mm. Son foyer est a 17,5mm de la face du collimateur. La reponse dans l'air pour une source ponctuelle placee sur l'axe central du co llimateur tombe a 10% de la valeur maximum a {+-} 7,5 mm du foyer. La reponse pour un champ eloigne est sensiblement meilleure dans les tissus que dans l'air, du fait de la forte attenuation des rayons gamma mous. Le memoire indique la reponse du collimateur pour une source ponctuelle dans l'air et a l'interieur de la boite cranienne. Ce collimateur a ete utilise pour mesurer, a l'aide de {sup 133}Xe, des flux sanguins localises dans la substance corticale du cerveau. Toutefois, l'appareil permet aussi de detecter, avec des produits chimiques marques par {sup 125}l, des tumeurs et des hemorragies de la substance corticale. (author) [Spanish] El autor describe un detector que consiste en un cristal de yoduro de sodio, de 5 pulg de diametro y i de pulg de espesor, y un colimador de enfoque profundo. En principio, el colimador fue diseflado para el estudio de la circulacion sanguinea en la corteza cerebral mediante el {sup 133}Xe, pero puede utilizarse tambien con otros emisores de rayos gamma blandos, por ejemplo, el {sup 125}I. El colimador, de plomo, tiene Inverted-Question-Mark de pulg de espesor y es de tipo multicanal. El foco esta situado a 1,75 cm de la cara anterior. La respuesta en aire a una fuente puntiforme que se mueva a lo largo del eje central del colimador decrece hasta el {sup 125}I del valor maximo a {+-} 0,75 cm del foco. La respuesta en tejidos para campos alejados es considerablemente mejor que en aire debido a que los tejidos atenuan mucho la radiacion gamma blanda. El autor describe la respuesta del colimador a una fuente puntiforme situada en el aire y dentro de un craneo. El colimador se ha empleado para medir, con ayuda de {sup 133}Xe, la circulacion sanguinea en la corteza cerebral; pero mediante productos quimicos marcados con {sup 125}I, permite tambien detectar hemorragias y tumores corticales. (author) [Russian] Opisyvaetsja detektor , sostojashhij iz kristalla iodistogo natrija dimetrom 12,5 sm i tolshhinoj 6,2 mm kollimatora s glubinnoj fokusirovkoj. Kollimator pervonachal'no prednaznachalsja dlja issledovanija krovoobrashhenija v kore golovnogo m o zga s pomoshh'ju ks en on a -133 , no mozhno takzhe ispol'zovat' i drugie mjagkie gamma-izluchajushhie i zo topy, naprimer j o d -125. Kollimator so svincovym korpusom tolshhinoj 6m m javljaetsja mnogokanal'nym. Fokus nahoditsja na rasstojanii 1,75 sm ot poverhnosti kollimatora. Chuvstvitel'nost' v vozduhe k tochechnomu istochniku po glavnoj osi kollimatora p adaet do 10% maksimal'noj velichiny na rasstojanii {+-} 0,75 cm ot fok u sa . Chuvstvitel'nost' dal'nego polja znachitel'no luchshe v tkani, chem v vozduhe vvidu bol'shogo oslablenija v tkani potoka mjagkih gamma-luchej. Privodjatsja dannye o chuvstvitel'nosti kollimatora k tochechnomu istochniku vvozd u h e i vnutri ch er ep a . Kollimator ispol'zovalsja dlja izmerenija m estn ogo krovotoka v kore golovnogo m ozga s pomoshh'ju ksenona 133. Odnako jetot apparat pozvoljaet s pomoshh'ju mechennyh jodom-125 preparatov obnaruzhivat' krovoizlijanija i opuholi kory golovnogo mozga . (author)}
place = {IAEA}
year = {1964}
month = {Oct}
}