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Simultaneous Determination of Glomerular Filtration Rate with {sup 125}I-Iothalamate and Effective Renal Plasma Flow with {sup 131}I-Hippuran

Abstract

The glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured in patients with normal and abnormal renal functions. {sup 125}I-iothalamate and inulin were used for the estimation of the GFR; {sup 131}I-Hippuran, p-aminohippuric acid and p-acetylaminohippuric acid were used for the ERPF determination. Procedure involved the continuous infusion of a solution containing {sup 125}I-iothalamate, {sup 131}I-Hippuran, inulin and PAH or PACAH, intravenously administered by an infusion pump. The clearances were determined in two ways: (1) By means of the standard technique, i.e. the equation, (urine concentration x urine volume)/plasma concentration: (2) By using the equation, intravenous dose per minute/plasma concentration. Comparisons between the methods are made. (author)
Authors:
Houwen, B.; Donker, A. J.M.; Woldring, M. G.; Beekhuis, H.; Zanten, A.K. van; Looye, A.; Hem, G.K. van der [1] 
  1. Department Of Internal Medicine, Central Isotope Laboratory, University of Groningen, Groningen (Netherlands)
Publication Date:
Feb 15, 1971
Product Type:
Conference
Report Number:
IAEA-SM-136/71
Resource Relation:
Conference: Symposium on Dynamics Studies with Radioisotopes in Clinical Medicine and Research, Rotterdam (Netherlands), 31 Aug - 4 Sep 1970; Other Information: 9 refs., 2 tabs., 2 figs.; Related Information: In: Dynamic Studies with Radioisotopes in Medicine. Proceedings of the Symposium on Dynamics Studies with Radioisotopes in Clinical Medicine and Research| 924 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HIPPURAN; INFUSION; INULIN; IODINE 125; IODINE 131; KIDNEYS; PATIENTS; STANDARDS; URINE
OSTI ID:
22127339
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M2752082418
Submitting Site:
INIS
Size:
page(s) 331-336
Announcement Date:
Sep 12, 2013

Citation Formats

Houwen, B., Donker, A. J.M., Woldring, M. G., Beekhuis, H., Zanten, A.K. van, Looye, A., and Hem, G.K. van der. Simultaneous Determination of Glomerular Filtration Rate with {sup 125}I-Iothalamate and Effective Renal Plasma Flow with {sup 131}I-Hippuran. IAEA: N. p., 1971. Web.
Houwen, B., Donker, A. J.M., Woldring, M. G., Beekhuis, H., Zanten, A.K. van, Looye, A., & Hem, G.K. van der. Simultaneous Determination of Glomerular Filtration Rate with {sup 125}I-Iothalamate and Effective Renal Plasma Flow with {sup 131}I-Hippuran. IAEA.
Houwen, B., Donker, A. J.M., Woldring, M. G., Beekhuis, H., Zanten, A.K. van, Looye, A., and Hem, G.K. van der. 1971. "Simultaneous Determination of Glomerular Filtration Rate with {sup 125}I-Iothalamate and Effective Renal Plasma Flow with {sup 131}I-Hippuran." IAEA.
@misc{etde_22127339,
title = {Simultaneous Determination of Glomerular Filtration Rate with {sup 125}I-Iothalamate and Effective Renal Plasma Flow with {sup 131}I-Hippuran}
author = {Houwen, B., Donker, A. J.M., Woldring, M. G., Beekhuis, H., Zanten, A.K. van, Looye, A., and Hem, G.K. van der}
abstractNote = {The glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured in patients with normal and abnormal renal functions. {sup 125}I-iothalamate and inulin were used for the estimation of the GFR; {sup 131}I-Hippuran, p-aminohippuric acid and p-acetylaminohippuric acid were used for the ERPF determination. Procedure involved the continuous infusion of a solution containing {sup 125}I-iothalamate, {sup 131}I-Hippuran, inulin and PAH or PACAH, intravenously administered by an infusion pump. The clearances were determined in two ways: (1) By means of the standard technique, i.e. the equation, (urine concentration x urine volume)/plasma concentration: (2) By using the equation, intravenous dose per minute/plasma concentration. Comparisons between the methods are made. (author)}
place = {IAEA}
year = {1971}
month = {Feb}
}