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Scintiscanning and Roentgenographic Procedures in Managing Major Pulmonary Disorders

Abstract

The need for practical methods which measure regional as well as integrated pulmonary functions is largely fulfilled by two types of scintiscanning procedure. Chest scanning after the intravenous injection of radioalbumin macroaggregates is a safe and widely applicable procedure for measuring relative arterial perfusion to all parts of the lung. The lung scan image is a photograhic pattern of pulmonary arterial blood flow. Its unique capacity to reveal localized ischemia makes scanning a valuable test of regional lung function, because oligemic lung can not conduct gas exchange normally. The scan has no diagnostic significance by itself but when interpreted in conjunction with chest films and pertinent clinical and laboratory data, scanning becomes a useful diagnostic adjunct and supplements the results of pulmonary function tests and roentgenographic procedures. Chest scanning after radioaerosol inhalation delineates the volume of aerated lung and gives a measure of regional alveolar ventilation in normal subjects and patients without obstructive airways disease. In patients with bronchogenic carcinoma, chronic bronchitis, bronchiectasis and emphysema, the inhalation scan reveals the site(s) of partial or total obstruction but does not give a true measure of alveolar ventilation. In such patients, repeated scans performed 6-18 hours later, when excessive aerosol deposits in  More>>
Authors:
Taplin, G. V.; Poe, N. D.; [1]  Dore, E. K.; [2]  Swanson, L. A.; Isawa, T.; [3]  Greenberg, A. [4] 
  1. UCLA School of Medicine, Los Angeles (United States)
  2. Memorial Hospital, Long Beach (United States)
  3. Los Angeles County Harbor General Hospital, Torrance (United States)
  4. Olive View Hospital, Olive View, CA (United States)
Publication Date:
May 15, 1969
Product Type:
Conference
Report Number:
IAEA-SM-108/116
Resource Relation:
Conference: Symposium on Medical Radioisotope Scintigraphy, Salzburg (Austria), 6-15 Aug 1968; Other Information: 15 refs., 6 figs.; Related Information: In: Medical Radioisotope Scintigraphy. Proceedings of a Symposium on Medical Radioisotope Scintigraphy. V. II| 952 p.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALBUMINS; BLOOD FLOW; BRONCHITIS; CARCINOMAS; CHEST; EMPHYSEMA; ENERGY SPECTRA; INTRAVENOUS INJECTION; IODINE 131; ISCHEMIA; LUNGS; SCINTISCANNING; TECHNETIUM 99
OSTI ID:
22107992
Research Organizations:
International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Contract Number:
Contract AT(04-1)GEN-12
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13M0473065803
Submitting Site:
INIS
Size:
page(s) 111-123
Announcement Date:
Jun 27, 2013

Citation Formats

Taplin, G. V., Poe, N. D., Dore, E. K., Swanson, L. A., Isawa, T., and Greenberg, A. Scintiscanning and Roentgenographic Procedures in Managing Major Pulmonary Disorders. IAEA: N. p., 1969. Web.
Taplin, G. V., Poe, N. D., Dore, E. K., Swanson, L. A., Isawa, T., & Greenberg, A. Scintiscanning and Roentgenographic Procedures in Managing Major Pulmonary Disorders. IAEA.
Taplin, G. V., Poe, N. D., Dore, E. K., Swanson, L. A., Isawa, T., and Greenberg, A. 1969. "Scintiscanning and Roentgenographic Procedures in Managing Major Pulmonary Disorders." IAEA.
@misc{etde_22107992,
title = {Scintiscanning and Roentgenographic Procedures in Managing Major Pulmonary Disorders}
author = {Taplin, G. V., Poe, N. D., Dore, E. K., Swanson, L. A., Isawa, T., and Greenberg, A.}
abstractNote = {The need for practical methods which measure regional as well as integrated pulmonary functions is largely fulfilled by two types of scintiscanning procedure. Chest scanning after the intravenous injection of radioalbumin macroaggregates is a safe and widely applicable procedure for measuring relative arterial perfusion to all parts of the lung. The lung scan image is a photograhic pattern of pulmonary arterial blood flow. Its unique capacity to reveal localized ischemia makes scanning a valuable test of regional lung function, because oligemic lung can not conduct gas exchange normally. The scan has no diagnostic significance by itself but when interpreted in conjunction with chest films and pertinent clinical and laboratory data, scanning becomes a useful diagnostic adjunct and supplements the results of pulmonary function tests and roentgenographic procedures. Chest scanning after radioaerosol inhalation delineates the volume of aerated lung and gives a measure of regional alveolar ventilation in normal subjects and patients without obstructive airways disease. In patients with bronchogenic carcinoma, chronic bronchitis, bronchiectasis and emphysema, the inhalation scan reveals the site(s) of partial or total obstruction but does not give a true measure of alveolar ventilation. In such patients, repeated scans performed 6-18 hours later, when excessive aerosol deposits in the airways are removed by the ciliary escalator mechanism, provide more reliable information on regional disturbances of alveolar ventilation. Both types of lung scintiscanning may be performed during the same visit by using radioactive test agents of widely different energy spectra, such as {sup 99m}Tc albumin aerosol followed by {sup 131}I albumin macroaggregates. This report reviews our five years clinical experience with chest scintiscanning and roentgenography in studying nearly 5000 patients with pulmonary disease. The major categories included: suspected pulmonary embolism, proven tuberculosis, chronic obstructive bronchopulmonary disease and bronchogenic carcinoma. Results are condensed by presenting representative case studies in each category, which illustrate the reproducibility and clinical value of scintiscanning performed in conjunction with roentgenographic procedures and pulmonary function measurements and interpreted in the light of the clinical findings and pertinent laboratory data. Finally, the limitations of current chest scanning procedures and test agents are discussed along with ways they can be minimized with rapid imaging devices and shortlived nuclides now becoming more readily available. (author)}
place = {IAEA}
year = {1969}
month = {May}
}