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Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT)

Journal Article:

Abstract

A method was investigated to measure gamma and fast neutron doses in phantoms exposed to an epithermal neutron beam designed for neutron capture therapy (NCT). The gamma dose component was measured by TLD-300 [CaF{sub 2}:Tm] and the fast neutron dose, mainly due to elastic scattering with hydrogen nuclei, was measured by alanine dosemeters [CH{sub 3}CH(NH{sub 2})COOH]. The gamma and fast neutron doses deposited in alanine dosemeters are very near to those released in tissue, because of the alanine tissue equivalence. Couples of TLD-300 and alanine dosemeters were irradiated in phantoms positioned in the epithermal column of the Tapiro reactor (ENEA-Casaccia RC). The dosemeter response depends on the linear energy transfer (LET) of radiation, hence the precision and reliability of the fast neutron dose values obtained with the proposed method have been investigated. Results showed that the combination of alanine and TLD detectors is a promising method to separate gamma dose and fast neutron dose in NCT. (authors)
Authors:
Cecilia, A.; Baccaro, S.; Cemmi, A.; [1]  Colli, V.; Gambarini, G.; [2]  Rosi, G.; [1]  Scolari, L. [2] 
  1. ENEA-FIS-ION, Casaccia RC, Via Anguillarese 301, 00060 Santa Maria di Galeria, Rome (Italy)
  2. Dept. of Physics of the Univ., INFN, Via Celoria 16, 20133 Milan (Italy)
Publication Date:
Jul 01, 2004
Product Type:
Journal Article
Resource Relation:
Journal Name: Radiation Protection Dosimetry; Journal Volume: 110; Journal Issue: 1-4; Conference: 9. Symposium on Neutron Dosimetry - Advances in nuclear particle dosimetry for radiation protection and medicine, Delft (Netherlands), 28 Sep - 3 Oct 2003; Other Information: Country of input: France; 15 refs.
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; 61 RADIATION PROTECTION AND DOSIMETRY; 62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; ALANINES; CALCIUM FLUORIDES; ELASTIC SCATTERING; EPITHERMAL NEUTRONS; FAST NEUTRONS; GAMMA RADIATION; LET; NEUTRON CAPTURE THERAPY; NEUTRON DIFFRACTION; NEUTRON DOSIMETRY; PHANTOMS; RADIATION DETECTION; RADIATION DETECTORS; RADIATION DOSES; TAPIRO REACTOR; THERMOLUMINESCENT DOSEMETERS; THERMOLUMINESCENT DOSIMETRY
OSTI ID:
22104143
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0144-8420; TRN: GB13V1701061964
Availability:
Available from doi: http://dx.doi.org/10.1093/rpd/nch108
Submitting Site:
INIS
Size:
page(s) 637-640
Announcement Date:
Jun 20, 2013

Journal Article:

Citation Formats

Cecilia, A., Baccaro, S., Cemmi, A., Colli, V., Gambarini, G., Rosi, G., and Scolari, L. Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT). United Kingdom: N. p., 2004. Web. doi:10.1093/RPD/NCH108.
Cecilia, A., Baccaro, S., Cemmi, A., Colli, V., Gambarini, G., Rosi, G., & Scolari, L. Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT). United Kingdom. doi:10.1093/RPD/NCH108.
Cecilia, A., Baccaro, S., Cemmi, A., Colli, V., Gambarini, G., Rosi, G., and Scolari, L. 2004. "Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT)." United Kingdom. doi:10.1093/RPD/NCH108. https://www.osti.gov/servlets/purl/10.1093/RPD/NCH108.
@misc{etde_22104143,
title = {Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT)}
author = {Cecilia, A., Baccaro, S., Cemmi, A., Colli, V., Gambarini, G., Rosi, G., and Scolari, L.}
abstractNote = {A method was investigated to measure gamma and fast neutron doses in phantoms exposed to an epithermal neutron beam designed for neutron capture therapy (NCT). The gamma dose component was measured by TLD-300 [CaF{sub 2}:Tm] and the fast neutron dose, mainly due to elastic scattering with hydrogen nuclei, was measured by alanine dosemeters [CH{sub 3}CH(NH{sub 2})COOH]. The gamma and fast neutron doses deposited in alanine dosemeters are very near to those released in tissue, because of the alanine tissue equivalence. Couples of TLD-300 and alanine dosemeters were irradiated in phantoms positioned in the epithermal column of the Tapiro reactor (ENEA-Casaccia RC). The dosemeter response depends on the linear energy transfer (LET) of radiation, hence the precision and reliability of the fast neutron dose values obtained with the proposed method have been investigated. Results showed that the combination of alanine and TLD detectors is a promising method to separate gamma dose and fast neutron dose in NCT. (authors)}
doi = {10.1093/RPD/NCH108}
journal = {Radiation Protection Dosimetry}
issue = {1-4}
volume = {110}
journal type = {AC}
place = {United Kingdom}
year = {2004}
month = {Jul}
}