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Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?

Abstract

The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery. (author)
Publication Date:
Jul 01, 2012
Product Type:
Journal Article
Resource Relation:
Journal Name: Quimica Nova; Journal Volume: 35; Journal Issue: 11
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ACETYL RADICALS; AQUATIC ECOSYSTEMS; CARBON 13; ETHANOL; HYDROGEN 1; LEAVES; MEDICINAL PLANTS; METABOLITES; NMR SPECTRA; STRUCTURAL CHEMICAL ANALYSIS; TERPENES; TOXICITY
OSTI ID:
22101247
Country of Origin:
Brazil
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0100-4042; TRN: BR13V0064058972
Availability:
Available from http://www.scielo.br/pdf/qn/v35n11/v35n11a36.pdf
Submitting Site:
BRN
Size:
page(s) 2278-2287
Announcement Date:
Jun 17, 2013

Citation Formats

Valli, Marilia, Pivatto, Marcos, Danuello, Amanda, Castro-Gamboa, Ian, Silva, Dulce Helena Siqueira, Cavalheiro, Alberto Jose, Araujo, Angela Regina, Furlan, Maysa, Lopes, Marcia Nasser, and Bolzani, Vanderlan da Silva, E-mail: bolzaniv@iq.unesp.br. Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?. Brazil: N. p., 2012. Web. doi:10.1590/S0100-40422012001100036.
Valli, Marilia, Pivatto, Marcos, Danuello, Amanda, Castro-Gamboa, Ian, Silva, Dulce Helena Siqueira, Cavalheiro, Alberto Jose, Araujo, Angela Regina, Furlan, Maysa, Lopes, Marcia Nasser, & Bolzani, Vanderlan da Silva, E-mail: bolzaniv@iq.unesp.br. Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?. Brazil. doi:10.1590/S0100-40422012001100036.
Valli, Marilia, Pivatto, Marcos, Danuello, Amanda, Castro-Gamboa, Ian, Silva, Dulce Helena Siqueira, Cavalheiro, Alberto Jose, Araujo, Angela Regina, Furlan, Maysa, Lopes, Marcia Nasser, and Bolzani, Vanderlan da Silva, E-mail: bolzaniv@iq.unesp.br. 2012. "Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?" Brazil. doi:10.1590/S0100-40422012001100036. https://www.osti.gov/servlets/purl/10.1590/S0100-40422012001100036.
@misc{etde_22101247,
title = {Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?}
author = {Valli, Marilia, Pivatto, Marcos, Danuello, Amanda, Castro-Gamboa, Ian, Silva, Dulce Helena Siqueira, Cavalheiro, Alberto Jose, Araujo, Angela Regina, Furlan, Maysa, Lopes, Marcia Nasser, and Bolzani, Vanderlan da Silva, E-mail: bolzaniv@iq.unesp.br}
abstractNote = {The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery. (author)}
doi = {10.1590/S0100-40422012001100036}
journal = {Quimica Nova}
issue = {11}
volume = {35}
journal type = {AC}
place = {Brazil}
year = {2012}
month = {Jul}
}