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Treatment of radiostrontium uptake in man; Traitement de la fixation de radiostrontium chez l'homme; Lechenie posledstvij pogloshcheniya radioaktivnogo strontsiya u cheloveka; Tratamiento de la radiotoxemla humana causada por absorcion de radioestroncio

Conference:

Abstract

In short-term experiments on rats the passage of radioactive strontium through the intestinal wall was modified by oral treatment using barium sulphate and normal calcium phosphate. However, in rats on a diet containing barium sulphate there was no change in the absorption of Sr{sup 90} given in drinking water. It was concluded that this substance could be of value in first-aid treatment only. In two cases of slight internal contamination following accidental Sr{sup 90} nitrate inhalation, barium sulphate (Skiabaryum Spofa) was administered orally within 10 and 30 min after the inhalation of Sr{sup 90}. The effectiveness of this treatment was tested in model experiments on rats performed under similar conditions as in the accidents. More recently, experiments on similar lines have been carried out on several cancer patients, in order to investigate further possibilities of first-aid treatment following acute internal radiostrontium contamination in man. (author) [French] Dans des experiences de breve duree sur les rats, le passage de radiostrontium a travers la paroi de l'intestin etait modifie par l'administration par voie buccale de sulfate de baryum et de phosphate de calcium normal. Toutefois, chez des rats dont le regime alimentaire contenait du sulfate de baryum, il n'y a pas eu  More>>
Authors:
Volf, V. [1] 
  1. Department of Ionizing Radiation Institute of Industrial Hygiene and Occupational Disease, Prague, CSSR (Czech Republic)
Publication Date:
Feb 15, 1963
Product Type:
Conference
Resource Relation:
Conference: Scientific meeting on the diagnosis and treatment of radioactive poisoning, Vienna (Austria), 15-18 Oct 1962; Other Information: 14 refs, 13 figs, 4 tabs; Related Information: In: Diagnosis and treatment of radioactive poisoning. Proceedings of the scientific meeting on the diagnosis and treatment of radioactive poisoning| 468 p.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; ABSORPTION; BARIUM SULFATES; CALCIUM PHOSPHATES; CONTAMINATION; DIET; DRINKING WATER; FIRST AID; INHALATION; NEOPLASMS; PATIENTS; RADIONUCLIDE KINETICS; RATS; STRONTIUM 90; UPTAKE
OSTI ID:
22097082
Research Organizations:
World Health Organization, Geneva (Switzerland); International Atomic Energy Agency, Vienna (Austria)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ISSN 0074-1884; TRN: XA13S0051055226
Submitting Site:
INIS
Size:
page(s) 131-144
Announcement Date:
May 23, 2013

Conference:

Citation Formats

Volf, V. Treatment of radiostrontium uptake in man; Traitement de la fixation de radiostrontium chez l'homme; Lechenie posledstvij pogloshcheniya radioaktivnogo strontsiya u cheloveka; Tratamiento de la radiotoxemla humana causada por absorcion de radioestroncio. IAEA: N. p., 1963. Web.
Volf, V. Treatment of radiostrontium uptake in man; Traitement de la fixation de radiostrontium chez l'homme; Lechenie posledstvij pogloshcheniya radioaktivnogo strontsiya u cheloveka; Tratamiento de la radiotoxemla humana causada por absorcion de radioestroncio. IAEA.
Volf, V. 1963. "Treatment of radiostrontium uptake in man; Traitement de la fixation de radiostrontium chez l'homme; Lechenie posledstvij pogloshcheniya radioaktivnogo strontsiya u cheloveka; Tratamiento de la radiotoxemla humana causada por absorcion de radioestroncio." IAEA.
@misc{etde_22097082,
title = {Treatment of radiostrontium uptake in man; Traitement de la fixation de radiostrontium chez l'homme; Lechenie posledstvij pogloshcheniya radioaktivnogo strontsiya u cheloveka; Tratamiento de la radiotoxemla humana causada por absorcion de radioestroncio}
author = {Volf, V.}
abstractNote = {In short-term experiments on rats the passage of radioactive strontium through the intestinal wall was modified by oral treatment using barium sulphate and normal calcium phosphate. However, in rats on a diet containing barium sulphate there was no change in the absorption of Sr{sup 90} given in drinking water. It was concluded that this substance could be of value in first-aid treatment only. In two cases of slight internal contamination following accidental Sr{sup 90} nitrate inhalation, barium sulphate (Skiabaryum Spofa) was administered orally within 10 and 30 min after the inhalation of Sr{sup 90}. The effectiveness of this treatment was tested in model experiments on rats performed under similar conditions as in the accidents. More recently, experiments on similar lines have been carried out on several cancer patients, in order to investigate further possibilities of first-aid treatment following acute internal radiostrontium contamination in man. (author) [French] Dans des experiences de breve duree sur les rats, le passage de radiostrontium a travers la paroi de l'intestin etait modifie par l'administration par voie buccale de sulfate de baryum et de phosphate de calcium normal. Toutefois, chez des rats dont le regime alimentaire contenait du sulfate de baryum, il n'y a pas eu de modification de l'absorption de {sup 90}Sr melange a l'eau de boisson. On en conclut que cette substance ne peut etre utile que pour un traitement de premiere urgence. Dans deux cas de legere contamination interne par inhalation accidentelle de {sup 90}Sr sous forme de nitrate, on a administre du sulfate de baryum (Skiabaryum Spofa) par voie buccale dans les 10 et les 30 min qui ont suivi l'inhalation de {sup 90}Sr. L'efficacite de ce traitement a ete etudiee au cours d'experiences temoins effectuees sur des rats dans des conditions identiques a celles des accidents. Plus recemment, on a procede a des experiences analogues sur plusieurs cancereux en vue de trouver d'autres possibilites de traitement de premiere urgence de la contamination interne aigue par le radiostrontium chez l'homme. (author) [Spanish] En experimentos de corta duracion realizados con ratas, se ha modificado la absorcion del radioestroncio a traves de la pared intestinal por tratamiento oral con sulfato barico y fosfato calcico normal. Por el contrario, ha permanecido inalterada la absorcion del ''9''0Sr administrado con el agua de bebida a ratas sometidas a un regimen que comprendia sulfato barico. De ello se deduce que esta sustancia solo puede ser de alguna utilidad en un tratamiento de primeros auxilios. En dos casos de ligera contaminacion interna consecutiva a la inhalacion accidental de nitrato de {sup 90}Sr se ha administrado suliato barico (Skiabaryum Spoia) por via oral a los 10 y 30 minutos de ocurrir la inhalacion. La eficacia de este tratamiento se ha verificado en experimentos realizados con ratas en las mismas condiciones en que se produjeron los accidentes. En fecha mas reciente, se han efectuado experimentos analogos en varios enfermos de cancer para estudiar otras posibilidades que ofrece el tratamiento de primeros auxilios, administrado a raiz de una contaminacion interna aguda causada por el radioestroncio en el organismo humano. (author) [Russian] V neprodolzhitel'nykh ehksperimentakh na krysakh izuchalos' izmenenie prokhozhdeniya radiostrontsiya cherez kishechnuyu stenku pod vliyaniem skarmlivaniya sernokislogo bariya i normal'nogo fosfornokislogo kal'tsiya. Odnako u krys, soderzhashchikhsya na diete, vklyuchayushchej sernokislyj barij, ne obnaruzheno izmenenij vsasyvaniya strontsiya-90, kotoryj zhivotnye poluchali s pit'evoj vodoj. Sdelan vyvod, chto ehto veshchestvo mozhet primenyat'sya lish' dlya okazaniya pervoj pomoshchi. V dvukh sluchayakh legkogo vnutrennego zarazheniya posle sluchajnogo vdykhaniya nitrata strontsiya-90 sernokislyj barij (Skiabarij Spofa) davalsya vnutr' cherez 10 i 30 minut posle vdykhaniya strontsiya-90. Ehivnoot' ehtogo lecheniya proveryalas' v ehksperimente na krysakh v tekh zhe usloviyakh, kotorye imeli mesto vo vremya intsidenta. Pozdnee byli issledovany neskol'ko rakovykh bol'nykh s tsel'yu izucheniya dal'nejshikh vozmozhnostej okazaniya pervoj pomoshchi pri ostrom vnutrennem otravlenii radiostrontsiem u cheloveka. (author)}
place = {IAEA}
year = {1963}
month = {Feb}
}