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Nanotechnology based diagnostics for neurological disorders

Journal Article:

Abstract

Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer's disease, Parkinson's disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and  More>>
Authors:
Kurek, Nicholas S; Chandra, Sathees B., E-mail: schandra@roosevelt.edu [1] 
  1. Department of Biological, Chemical and Physical Sciences, Roosevelt University, Chicago, IL (United States)
Publication Date:
Jul 01, 2012
Product Type:
Journal Article
Resource Relation:
Journal Name: ARBS. Annual Review of Biomedical Sciences; Journal Volume: . 14
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSIS; DIAGNOSTIC TECHNIQUES; GENETICS; MOLECULAR BIOLOGY; NANOSTRUCTURES; NERVOUS SYSTEM DISEASES; THERAPEUTIC USES
OSTI ID:
22048300
Country of Origin:
Brazil
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1517-3011; TRN: BR1300001007781
Availability:
Available from http://arbs.biblioteca.unesp.br/index.php/arbs/article/view/165/162
Submitting Site:
BRN
Size:
page(s) 1-15
Announcement Date:
Feb 13, 2013

Journal Article:

Citation Formats

Kurek, Nicholas S, and Chandra, Sathees B., E-mail: schandra@roosevelt.edu. Nanotechnology based diagnostics for neurological disorders. Brazil: N. p., 2012. Web.
Kurek, Nicholas S, & Chandra, Sathees B., E-mail: schandra@roosevelt.edu. Nanotechnology based diagnostics for neurological disorders. Brazil.
Kurek, Nicholas S, and Chandra, Sathees B., E-mail: schandra@roosevelt.edu. 2012. "Nanotechnology based diagnostics for neurological disorders." Brazil.
@misc{etde_22048300,
title = {Nanotechnology based diagnostics for neurological disorders}
author = {Kurek, Nicholas S, and Chandra, Sathees B., E-mail: schandra@roosevelt.edu}
abstractNote = {Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer's disease, Parkinson's disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and medicine. In this article, we will discuss and analyze many novel nanotechnology based diagnostic techniques at our disposal today. (author)}
journal = {ARBS. Annual Review of Biomedical Sciences}
volume = {. 14}
journal type = {AC}
place = {Brazil}
year = {2012}
month = {Jul}
}