Abstract
The global environmental pollution is responsible for the exposure of living beings to the influence of various technogenic factors, including ionizing radiation. Exposure to such radiation represents a genuine, increasing threat to mankind and our environment. The steadily increasing applications of radiation in clinical practice, industrial and agricultural activities, residual radio-activity resulting from nuclear test explosions, have a measurable impact contributing to significant radiation hazards in humans. Further, the proliferation of terrorism and asymmetric warfare in the 21st century has rendered the modern world a dangerous place to live and work. With the realization of deleterious effects of ionizing radiation, a need was felt to protect human beings against these harmful effects by using physical and/or chemical means. Many chemical compounds have been tested for radio protective action but their practical applicability remained limited owing to their inherent toxicity at the optimum dose level. Various plants have been used for various ailments in humans since time immemorial, and herbal preparations have usually been considered safe and less toxic than the synthetic compounds. Therefore, screening of natural products present a major avenue for the discovery of new radio protective drugs and such products have drawn the attention of investigators during the
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Goyal, P.K., E-mail: pkgoyal2002@gmail.com
[1]
- Radiation and Cancer Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur (India)
Citation Formats
Goyal, P.K., E-mail: pkgoyal2002@gmail.com.
Modulation of radiosensitivity of biological systems by medicinal herbs.
India: N. p.,
2012.
Web.
Goyal, P.K., E-mail: pkgoyal2002@gmail.com.
Modulation of radiosensitivity of biological systems by medicinal herbs.
India.
Goyal, P.K., E-mail: pkgoyal2002@gmail.com.
2012.
"Modulation of radiosensitivity of biological systems by medicinal herbs."
India.
@misc{etde_22026938,
title = {Modulation of radiosensitivity of biological systems by medicinal herbs}
author = {Goyal, P.K., E-mail: pkgoyal2002@gmail.com}
abstractNote = {The global environmental pollution is responsible for the exposure of living beings to the influence of various technogenic factors, including ionizing radiation. Exposure to such radiation represents a genuine, increasing threat to mankind and our environment. The steadily increasing applications of radiation in clinical practice, industrial and agricultural activities, residual radio-activity resulting from nuclear test explosions, have a measurable impact contributing to significant radiation hazards in humans. Further, the proliferation of terrorism and asymmetric warfare in the 21st century has rendered the modern world a dangerous place to live and work. With the realization of deleterious effects of ionizing radiation, a need was felt to protect human beings against these harmful effects by using physical and/or chemical means. Many chemical compounds have been tested for radio protective action but their practical applicability remained limited owing to their inherent toxicity at the optimum dose level. Various plants have been used for various ailments in humans since time immemorial, and herbal preparations have usually been considered safe and less toxic than the synthetic compounds. Therefore, screening of natural products present a major avenue for the discovery of new radio protective drugs and such products have drawn the attention of investigators during the last two decades. The Indian system of medicine employs a large number of plants and some of these herbals viz. The extracts of certain medicinal plant like Amla (Emblica officinalis), Rosemary (Rosemary officinalis), Methi (Trigonella foenum graecum) sapthaparna (Alstonia scholaris), Bael (Aegle inarmelos), Bhumi amla (Phyllanthus niruri), Jamun (Syzgium cumini), Gloe (Tinospora cordifolia) have been trialed in this laboratory for their radio protective action in various biological systems of mammals. The extracts of various parts of such plants have appreciable DRF on the basis of survival data as well as these have been found in inhibiting radiation induced hematological, cytological, biochemical and oxidative stress. Such Indian medicinal plants may prove to be a promising future source of nontoxic radio modifiers in mammals; however, further studies are needed to explore their clinical potential for cancer research. (author)}
place = {India}
year = {2012}
month = {Jul}
}
title = {Modulation of radiosensitivity of biological systems by medicinal herbs}
author = {Goyal, P.K., E-mail: pkgoyal2002@gmail.com}
abstractNote = {The global environmental pollution is responsible for the exposure of living beings to the influence of various technogenic factors, including ionizing radiation. Exposure to such radiation represents a genuine, increasing threat to mankind and our environment. The steadily increasing applications of radiation in clinical practice, industrial and agricultural activities, residual radio-activity resulting from nuclear test explosions, have a measurable impact contributing to significant radiation hazards in humans. Further, the proliferation of terrorism and asymmetric warfare in the 21st century has rendered the modern world a dangerous place to live and work. With the realization of deleterious effects of ionizing radiation, a need was felt to protect human beings against these harmful effects by using physical and/or chemical means. Many chemical compounds have been tested for radio protective action but their practical applicability remained limited owing to their inherent toxicity at the optimum dose level. Various plants have been used for various ailments in humans since time immemorial, and herbal preparations have usually been considered safe and less toxic than the synthetic compounds. Therefore, screening of natural products present a major avenue for the discovery of new radio protective drugs and such products have drawn the attention of investigators during the last two decades. The Indian system of medicine employs a large number of plants and some of these herbals viz. The extracts of certain medicinal plant like Amla (Emblica officinalis), Rosemary (Rosemary officinalis), Methi (Trigonella foenum graecum) sapthaparna (Alstonia scholaris), Bael (Aegle inarmelos), Bhumi amla (Phyllanthus niruri), Jamun (Syzgium cumini), Gloe (Tinospora cordifolia) have been trialed in this laboratory for their radio protective action in various biological systems of mammals. The extracts of various parts of such plants have appreciable DRF on the basis of survival data as well as these have been found in inhibiting radiation induced hematological, cytological, biochemical and oxidative stress. Such Indian medicinal plants may prove to be a promising future source of nontoxic radio modifiers in mammals; however, further studies are needed to explore their clinical potential for cancer research. (author)}
place = {India}
year = {2012}
month = {Jul}
}