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Total chemical analysis of melanoma using analytical methods ToF-SIMS; Totalna chemicka analyza Melanomu pomocou analytickej metody ToF-SIMS

Abstract

Cancer research is now one of the fastest growing branch of science. It is a subject of interest of physicians, biochemists and chemists. So we decided to use the available technologies of analytical chemistry to determine the structural and metabolic aberrations. Cancer itself is defined as an uncontrolled multiplication of cells. Cells need to multiply, of course, food and draw it out of the body affected by cancer proliferation. We focused on skin cancer because at first glance there is a clear difference between a healthy skin and melanoma, even if not necessarily everything that does not look like a healthy skin must be melanoma. According to appearance it may be an innocent formation known as a birthmark that may degenerate into cancer, however it can also be a benign tumour. The aim of this paper is to identify the structure and optionally metabolites of malonamic cells in comparison with healthy skin, using physico-chemical and analytical methods. Our main tool for reaching the aim is ToF-SIMS method. (authors)
Authors:
Kadasiova, M; Prochazka, M; Stupavska, M; [1]  Velic, D [2] 
  1. Univerzita Komenskeho v Bratislave, Prirodovedecka fakulta, Katedra fyzikalnej a teoretickej chemie, 84215 Bratislava (Slovakia)
  2. Univerzita Komenskeho v Bratislave, Prirodovedecka fakulta, Katedra fyzikalnej a teoretickej chemie, 84215 Bratislava and Medzinarodne laserove centrum, 84104 Bratislava (Slovakia)
Publication Date:
Apr 25, 2012
Product Type:
Conference
Report Number:
INIS-SK-2012-066
Resource Relation:
Conference: Student Scientific Conference PriF UK 2012, Studentska vedecka konferencia Prif UK 2012, Bratislava (Slovakia), 25 Apr 2012; Other Information: 5 figs., 2 refs.; Related Information: In: Student Scientific Conference PriF UK 2012. Proceedings of reviewed contributions| by Galambos, M. (ed.) [Department of Nuclear Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)]; Dzugasova, V. (ed.) [Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)]| 1634 p.
Subject:
60 APPLIED LIFE SCIENCES; DIAGNOSTIC TECHNIQUES; EXPERIMENTAL DATA; ION MICROPROBE ANALYSIS; MASS SPECTROSCOPY; MELANOMAS; SKIN; SKIN DISEASES
OSTI ID:
22012458
Research Organizations:
Faculty of Natural Sciences, Comenius University, Bratislava (Slovakia)
Country of Origin:
Slovakia
Language:
Slovak
Contract Number:
Project meta-QUTE and APVV-0491-07
Other Identifying Numbers:
Other: ISBN 978-80-223-3213-2; TRN: SK12K0301099559
Availability:
Available from INIS in electronic form. Also available from http://2012.svkprifuk.info/zbornik/zbornik.pdf
Submitting Site:
INIS
Size:
page(s) 878-883
Announcement Date:
Jan 03, 2013

Citation Formats

Kadasiova, M, Prochazka, M, Stupavska, M, and Velic, D. Total chemical analysis of melanoma using analytical methods ToF-SIMS; Totalna chemicka analyza Melanomu pomocou analytickej metody ToF-SIMS. Slovakia: N. p., 2012. Web.
Kadasiova, M, Prochazka, M, Stupavska, M, & Velic, D. Total chemical analysis of melanoma using analytical methods ToF-SIMS; Totalna chemicka analyza Melanomu pomocou analytickej metody ToF-SIMS. Slovakia.
Kadasiova, M, Prochazka, M, Stupavska, M, and Velic, D. 2012. "Total chemical analysis of melanoma using analytical methods ToF-SIMS; Totalna chemicka analyza Melanomu pomocou analytickej metody ToF-SIMS." Slovakia.
@misc{etde_22012458,
title = {Total chemical analysis of melanoma using analytical methods ToF-SIMS; Totalna chemicka analyza Melanomu pomocou analytickej metody ToF-SIMS}
author = {Kadasiova, M, Prochazka, M, Stupavska, M, and Velic, D}
abstractNote = {Cancer research is now one of the fastest growing branch of science. It is a subject of interest of physicians, biochemists and chemists. So we decided to use the available technologies of analytical chemistry to determine the structural and metabolic aberrations. Cancer itself is defined as an uncontrolled multiplication of cells. Cells need to multiply, of course, food and draw it out of the body affected by cancer proliferation. We focused on skin cancer because at first glance there is a clear difference between a healthy skin and melanoma, even if not necessarily everything that does not look like a healthy skin must be melanoma. According to appearance it may be an innocent formation known as a birthmark that may degenerate into cancer, however it can also be a benign tumour. The aim of this paper is to identify the structure and optionally metabolites of malonamic cells in comparison with healthy skin, using physico-chemical and analytical methods. Our main tool for reaching the aim is ToF-SIMS method. (authors)}
place = {Slovakia}
year = {2012}
month = {Apr}
}