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Lipid Profile in Sudanese Diabetic Patients

Abstract

This study composes of two parts, the first one is an experiment to evaluate the level of blood glucose and lipid profile (TC, TG, LDL, HDL and VLDL) among diabetic patients and comparison of the result with non diabetic subjects and the second one is a survey to assess the standards of health care and patients knowledge. The subject were divided into two groups according to insulin requirement. Type 1 is insulin dependent diabetes mellitus and type 2 is non insulin dependent diabetes mellitus and then divided according to gender (males and female) subgroups. The study subjects selected for this study consist of one hundred Sudanese diabetic patients from Ribat University Hospital during January 2009 they had mean age (52{+-}11.063) years,a mean height (165.82{+-}8.573) cm and a mean weight of (70.20{+-}11.203) kg. fifty healthy non diabetic subject were chosen as controls, their mean age (45.72{+-}11.169) years, mean height (167.28{+-}9.450) cm and mean weight (71.02{+-}13.429) kg. Blood glucose and lipid profile total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) were measured by enzymatic colorimetric methods in both groups, and very low density lipoprotein cholesterol were calculated for each sample. All patients were interviewed and filled  More>>
Authors:
Naway, L M. Y. [1] 
  1. Sudan Academy of Sciences, Atomic Energy Council, Khartoum (Sudan)
Publication Date:
Apr 15, 2011
Product Type:
Thesis/Dissertation
Report Number:
INIS-SD-422
Resource Relation:
Other Information: TH: Thesis (M.Sc); 188 refs., 3 tabs., 6 figs., 2app
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD PLASMA; COMPARATIVE EVALUATIONS; DIABETES MELLITUS; GLUCOSE; LEVELS; LIPIDS; NUMERICAL DATA; PATIENTS; SPECTROPHOTOMETRY; SUDAN; AFRICA; ALDEHYDES; ARAB COUNTRIES; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; CARBOHYDRATES; DATA; DEVELOPING COUNTRIES; DISEASES; ENDOCRINE DISEASES; EVALUATION; HEXOSES; INFORMATION; MATERIALS; METABOLIC DISEASES; MONOSACCHARIDES; ORGANIC COMPOUNDS; SACCHARIDES
OSTI ID:
21557310
Research Organizations:
Sudan Academy of Sciences, Khartoum (Sudan)
Country of Origin:
Sudan
Language:
English
Other Identifying Numbers:
TRN: SD1200002035334
Availability:
Available from INIS in electronic form. Also available from Sudan atomic energy commission, Khartoum (SD)
Submitting Site:
INIS
Size:
89 pages
Announcement Date:
May 31, 2012

Citation Formats

Naway, L M. Y. Lipid Profile in Sudanese Diabetic Patients. Sudan: N. p., 2011. Web.
Naway, L M. Y. Lipid Profile in Sudanese Diabetic Patients. Sudan.
Naway, L M. Y. 2011. "Lipid Profile in Sudanese Diabetic Patients." Sudan.
@misc{etde_21557310,
title = {Lipid Profile in Sudanese Diabetic Patients}
author = {Naway, L M. Y.}
abstractNote = {This study composes of two parts, the first one is an experiment to evaluate the level of blood glucose and lipid profile (TC, TG, LDL, HDL and VLDL) among diabetic patients and comparison of the result with non diabetic subjects and the second one is a survey to assess the standards of health care and patients knowledge. The subject were divided into two groups according to insulin requirement. Type 1 is insulin dependent diabetes mellitus and type 2 is non insulin dependent diabetes mellitus and then divided according to gender (males and female) subgroups. The study subjects selected for this study consist of one hundred Sudanese diabetic patients from Ribat University Hospital during January 2009 they had mean age (52{+-}11.063) years,a mean height (165.82{+-}8.573) cm and a mean weight of (70.20{+-}11.203) kg. fifty healthy non diabetic subject were chosen as controls, their mean age (45.72{+-}11.169) years, mean height (167.28{+-}9.450) cm and mean weight (71.02{+-}13.429) kg. Blood glucose and lipid profile total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) were measured by enzymatic colorimetric methods in both groups, and very low density lipoprotein cholesterol were calculated for each sample. All patients were interviewed and filled out the questionnaire consisted of five parts. The result of the study found highly significant elevated level of blood glucose level among diabetic patients compared to non diabetic subjects. In addition to significant elevated level of serum lipids TC p=0.001, TG p=0.001, LDL p=0.001, and VLDL p=0.001. And decrease in HDL P=0.001 level in diabetic patient compared to non diabetic subjects. Among subgroups (type 1, type 2) diabetic patients glucose level and serum total cholesterol, triglycerides, LDL cholesterol and VLDL cholestrol were significantly higher (p<0.5) while HDL cholestrol was significantly lower when compared to non diabetic subjects. Non statistically variation was found in the level of glucose and lipid between males and females diabetic patients. A statistically positive correlation was found between blood glucose level and cholesterol (r=0.02), triglyceride (r=0.052), LDL-C (r=0.023) and VLDL-C (r=0.056). Negative correlation between glucose and HDL-C (r=0.028). Positive correlation were found between plasma glucose, and serum cholesterol, triglyceride, LDL-C, VLDL-C and duration of diabetes. (r=0.070), (r=0.023), (r=0.009), (r=0.0075), (r=0.009) respectively. Negative correlation between HDL-C and duration of diabetes (r=0.12). The study indicated that standards of health care that many patients are unaware of the symptoms of diabetic complications and the effect of diabetes on kidneys, heart diseases, in addition decreased sexual performance in men (82%) than women (4%). The study conclude that higher level of cholesterol, triglyceride, LDL-cholesterol and VLDL cholesterol in diabetic patient compared to non diabetic subjects with lower level of serum HDL cholesterol in diabetic patient compared to non diabetic subjects. The majority of diabetic patients are unaware of their health states. Male diabetic patients should be screened for sexual performance to avoid impotence.(Author)}
place = {Sudan}
year = {2011}
month = {Apr}
}