Abstract
To evaluate the diagnostic accuracy of contrast-enhanced MR angiography (CE-MRA) and the added benefit of unenhanced proton MR angiography compared with CT pulmonary angiography (CTPA) in patients with chronic thromboembolic disease (CTE). A 2 year retrospective study of 53 patients with chronic thromboembolic pulmonary hypertension who underwent CTPA and MRI for suspected pulmonary hypertension and a control group of 36 patients with no CT evidence of pulmonary embolism. The MRI was evaluated for CTE and the combined diagnostic accuracy of ce-MRA and unenhanced proton MRA was determined. CE-MRA generated lung perfusion maps were also assessed. The overall sensitivity and specificity of CE-MRA in diagnosing proximal and distal CTE were 98% and 94%, respectively. The sensitivity improved from 50% to 88% for central vessel disease when CE-MRA images were analysed with unenhanced proton MRA. The CE-MRA identified more stenoses (29/18), post-stenosis dilatation (23/7) and occlusions (37/29) compared with CTPA. The CE-MRA perfusion images showed a sensitivity of 92% for diagnosing CTE. CE-MRA has high sensitivity and specificity for diagnosing CTE. The sensitivity of CE-MRA for visualisation of adherent central and lobar thrombus significantly improves with the addition of unenhanced proton MRA which delineates the vessel wall. (orig.)
Rajaram, Smitha;
[1]
Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)];
Swift, Andrew J;
Wild, Jim M;
[1]
Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)];
Capener, David;
Telfer, Adam;
[1]
Davies, Christine;
Hill, Catherine;
[2]
Condliffe, Robin;
Elliot, Charles;
Kiely, David G;
[3]
Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)];
Hurdman, Judith
[3]
- Unit of Academic Radiology, University of Sheffield, Sheffield (United Kingdom)
- Sheffield Teaching Hospitals Trust, Department of Radiology, Sheffield (United Kingdom)
- Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield (United Kingdom)
Citation Formats
Rajaram, Smitha, Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)], Swift, Andrew J, Wild, Jim M, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], Capener, David, Telfer, Adam, Davies, Christine, Hill, Catherine, Condliffe, Robin, Elliot, Charles, Kiely, David G, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], and Hurdman, Judith.
Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension.
Germany: N. p.,
2012.
Web.
doi:10.1007/S00330-011-2252-X.
Rajaram, Smitha, Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)], Swift, Andrew J, Wild, Jim M, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], Capener, David, Telfer, Adam, Davies, Christine, Hill, Catherine, Condliffe, Robin, Elliot, Charles, Kiely, David G, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], & Hurdman, Judith.
Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension.
Germany.
https://doi.org/10.1007/S00330-011-2252-X
Rajaram, Smitha, Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)], Swift, Andrew J, Wild, Jim M, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], Capener, David, Telfer, Adam, Davies, Christine, Hill, Catherine, Condliffe, Robin, Elliot, Charles, Kiely, David G, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], and Hurdman, Judith.
2012.
"Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension."
Germany.
https://doi.org/10.1007/S00330-011-2252-X.
@misc{etde_21545120,
title = {Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension}
author = {Rajaram, Smitha, Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)], Swift, Andrew J, Wild, Jim M, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], Capener, David, Telfer, Adam, Davies, Christine, Hill, Catherine, Condliffe, Robin, Elliot, Charles, Kiely, David G, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], and Hurdman, Judith}
abstractNote = {To evaluate the diagnostic accuracy of contrast-enhanced MR angiography (CE-MRA) and the added benefit of unenhanced proton MR angiography compared with CT pulmonary angiography (CTPA) in patients with chronic thromboembolic disease (CTE). A 2 year retrospective study of 53 patients with chronic thromboembolic pulmonary hypertension who underwent CTPA and MRI for suspected pulmonary hypertension and a control group of 36 patients with no CT evidence of pulmonary embolism. The MRI was evaluated for CTE and the combined diagnostic accuracy of ce-MRA and unenhanced proton MRA was determined. CE-MRA generated lung perfusion maps were also assessed. The overall sensitivity and specificity of CE-MRA in diagnosing proximal and distal CTE were 98% and 94%, respectively. The sensitivity improved from 50% to 88% for central vessel disease when CE-MRA images were analysed with unenhanced proton MRA. The CE-MRA identified more stenoses (29/18), post-stenosis dilatation (23/7) and occlusions (37/29) compared with CTPA. The CE-MRA perfusion images showed a sensitivity of 92% for diagnosing CTE. CE-MRA has high sensitivity and specificity for diagnosing CTE. The sensitivity of CE-MRA for visualisation of adherent central and lobar thrombus significantly improves with the addition of unenhanced proton MRA which delineates the vessel wall. (orig.)}
doi = {10.1007/S00330-011-2252-X}
journal = []
issue = {2}
volume = {22}
place = {Germany}
year = {2012}
month = {Feb}
}
title = {Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension}
author = {Rajaram, Smitha, Academic Unit of Radiology, C Floor, Royal Hallamshire Hospital, Sheffield (United Kingdom)], Swift, Andrew J, Wild, Jim M, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], Capener, David, Telfer, Adam, Davies, Christine, Hill, Catherine, Condliffe, Robin, Elliot, Charles, Kiely, David G, Sheffield Cardiovascular Biomedical Research Unit, Sheffield (United Kingdom)], and Hurdman, Judith}
abstractNote = {To evaluate the diagnostic accuracy of contrast-enhanced MR angiography (CE-MRA) and the added benefit of unenhanced proton MR angiography compared with CT pulmonary angiography (CTPA) in patients with chronic thromboembolic disease (CTE). A 2 year retrospective study of 53 patients with chronic thromboembolic pulmonary hypertension who underwent CTPA and MRI for suspected pulmonary hypertension and a control group of 36 patients with no CT evidence of pulmonary embolism. The MRI was evaluated for CTE and the combined diagnostic accuracy of ce-MRA and unenhanced proton MRA was determined. CE-MRA generated lung perfusion maps were also assessed. The overall sensitivity and specificity of CE-MRA in diagnosing proximal and distal CTE were 98% and 94%, respectively. The sensitivity improved from 50% to 88% for central vessel disease when CE-MRA images were analysed with unenhanced proton MRA. The CE-MRA identified more stenoses (29/18), post-stenosis dilatation (23/7) and occlusions (37/29) compared with CTPA. The CE-MRA perfusion images showed a sensitivity of 92% for diagnosing CTE. CE-MRA has high sensitivity and specificity for diagnosing CTE. The sensitivity of CE-MRA for visualisation of adherent central and lobar thrombus significantly improves with the addition of unenhanced proton MRA which delineates the vessel wall. (orig.)}
doi = {10.1007/S00330-011-2252-X}
journal = []
issue = {2}
volume = {22}
place = {Germany}
year = {2012}
month = {Feb}
}